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{"topic_id": "1", "languages_with_qrels": [], "topics": [{"lang": "eng", "source": "original", "topic_title": "human reproductive system", "topic_description": "I am looking for articles describing the human reproductive system.", "topic_narrative": "Articles describing the human reproductive system in biological terms from the perspective of a modern biologist are considered relevant. Articles describing the overall system such as a general description of the components or a lower level description such as specific cellular or molecular pathways involved in either the early development or adult stage maintenance of the systemo are relevant. Descriptions of mammalian reproductive system in general are considere somewhat valuable. Articles describing the reproductive system of a species outside of the class of mammalia are not relevant. Articles talking about human reproduction from other perspectives outside that of the biological sciences, such as from a historical or political perspective are not relevant."}, {"lang": "zho", "source": "human translation", "topic_title": "\u4eba\u7c7b\u751f\u6b96\u7cfb\u7edf", "topic_description": "\u6211\u5e0c\u671b\u627e\u5230\u5173\u4e8e\u4eba\u7c7b\u751f\u6b96\u7cfb\u7edf\u7684\u6587\u7ae0\u3002", "topic_narrative": ""}, {"lang": "zho", "source": "google translation", "topic_title": "\u4eba\u7c7b\u751f\u6b96\u7cfb\u7edf", "topic_description": "\u6211\u6b63\u5728\u5bfb\u627e\u63cf\u8ff0\u4eba\u7c7b\u751f\u6b96\u7cfb\u7edf\u7684\u6587\u7ae0\u3002", "topic_narrative": "\u4ece\u73b0\u4ee3\u751f\u7269\u5b66\u5bb6\u7684\u89d2\u5ea6\u7528\u751f\u7269\u5b66\u672f\u8bed\u63cf\u8ff0\u4eba\u7c7b\u751f\u6b96\u7cfb\u7edf\u7684\u6587\u7ae0\u88ab\u8ba4\u4e3a\u662f\u76f8\u5173\u7684\u3002\u63cf\u8ff0\u6574\u4e2a\u7cfb\u7edf\u7684\u6587\u7ae0\uff08\u4f8b\u5982\u7ec4\u4ef6\u7684\u4e00\u822c\u63cf\u8ff0\uff09\u6216\u8f83\u4f4e\u7ea7\u522b\u7684\u63cf\u8ff0\uff08\u4f8b\u5982\u6d89\u53ca\u7cfb\u7edf\u65e9\u671f\u53d1\u80b2\u6216\u6210\u5e74\u9636\u6bb5\u7ef4\u62a4\u7684\u7279\u5b9a\u7ec6\u80de\u6216\u5206\u5b50\u9014\u5f84\uff09\u662f\u76f8\u5173\u7684\u3002\u4e00\u822c\u800c\u8a00\uff0c\u5bf9\u54fa\u4e73\u52a8\u7269\u751f\u6b96\u7cfb\u7edf\u7684\u63cf\u8ff0\u88ab\u8ba4\u4e3a\u5177\u6709\u4e00\u5b9a\u7684\u4ef7\u503c\u3002\u63cf\u8ff0\u54fa\u4e73\u52a8\u7269\u7eb2\u4ee5\u5916\u7269\u79cd\u7684\u751f\u6b96\u7cfb\u7edf\u7684\u6587\u7ae0\u4e0d\u76f8\u5173\u3002\u4ece\u751f\u7269\u79d1\u5b66\u4e4b\u5916\u7684\u5176\u4ed6\u89d2\u5ea6\uff08\u4f8b\u5982\u4ece\u5386\u53f2\u6216\u653f\u6cbb\u89d2\u5ea6\uff09\u8ba8\u8bba\u4eba\u7c7b\u751f\u6b96\u7684\u6587\u7ae0\u662f\u4e0d\u76f8\u5173\u7684\u3002"}]}
{"topic_id": "2", "languages_with_qrels": [], "topics": [{"lang": "eng", "source": "original", "topic_title": "lipid-based drug delivery through BBB", "topic_description": "I am looking for information on the progress on lipid-based nanovectors on penetrating the blood-brain barrier (BBB) and design examples that can facilitate lipid-based vectors crossing the BBB.", "topic_narrative": "Research papers that focus on lipid-based vectors (lipsomes, lipid nanoparticles, solid lipid-nanoparticles) crossing the blood-brain barrier (BBB) and documents that summarize research progress and explain how lipid-based vectors can be used to penetrate the BBB are considered relevant. Documents discussing different cargos would be considered somewhat valuable. Documents that discuss BBB penetration in other contexts that do not include lipid-based vectors are not that valuable. Documents that explain the importance or biological structure of the BBB are not relevant and non-lipid-based vectors are also irrelevant."}, {"lang": "zho", "source": "human translation", "topic_title": "\u7a7f\u900f\u8840\u8111\u5c4f\u969c(BBB)\u7684\u8102\u8d28\u836f\u7269\u9012\u9001\u8f7d\u4f53", "topic_description": "\u6211\u60f3\u5bfb\u627e\u5173\u4e8e\u80fd\u7a7f\u900f\u8840\u8111\u5c4f\u969c\u7684\u8102\u8d28\u8f7d\u4f53\u7684\u7814\u7a76\u8fdb\u5c55\u4ee5\u53ca\u80fd\u8f85\u52a9\u8102\u8d28\u8f7d\u4f53\u7a7f\u900f\u8840\u8111\u5c4f\u969c\u7684\u8bbe\u8ba1\u3002", "topic_narrative": ""}, {"lang": "zho", "source": "google translation", "topic_title": "\u901a\u8fc7 BBB \u8fdb\u884c\u8102\u8d28\u836f\u7269\u8f93\u9001", "topic_description": "\u6211\u6b63\u5728\u5bfb\u627e\u6709\u5173\u57fa\u4e8e\u8102\u8d28\u7684\u7eb3\u7c73\u8f7d\u4f53\u7a7f\u900f\u8840\u8111\u5c4f\u969c (BBB) \u7684\u8fdb\u5c55\u7684\u4fe1\u606f\uff0c\u4ee5\u53ca\u53ef\u4ee5\u4fc3\u8fdb\u57fa\u4e8e\u8102\u8d28\u7684\u8f7d\u4f53\u7a7f\u8fc7 BBB \u7684\u8bbe\u8ba1\u793a\u4f8b\u3002", "topic_narrative": "\u91cd\u70b9\u5173\u6ce8\u8102\u8d28\u8f7d\u4f53\uff08\u8102\u8d28\u4f53\u3001\u8102\u8d28\u7eb3\u7c73\u9897\u7c92\u3001\u56fa\u4f53\u8102\u8d28\u7eb3\u7c73\u9897\u7c92\uff09\u7a7f\u8fc7\u8840\u8111\u5c4f\u969c\uff08BBB\uff09\u7684\u7814\u7a76\u8bba\u6587\u4ee5\u53ca\u603b\u7ed3\u7814\u7a76\u8fdb\u5c55\u5e76\u89e3\u91ca\u5982\u4f55\u4f7f\u7528\u8102\u8d28\u8f7d\u4f53\u7a7f\u900f\u8840\u8111\u5c4f\u969c\u7684\u6587\u4ef6\u8ba4\u4e3a\u76f8\u5173\u3002\u8ba8\u8bba\u4e0d\u540c\u8d27\u7269\u7684\u6587\u4ef6\u5c06\u88ab\u8ba4\u4e3a\u5177\u6709\u4e00\u5b9a\u7684\u4ef7\u503c\u3002\u5728\u4e0d\u5305\u62ec\u57fa\u4e8e\u8102\u8d28\u7684\u8f7d\u4f53\u7684\u5176\u4ed6\u60c5\u51b5\u4e0b\u8ba8\u8bba BBB \u6e17\u900f\u7684\u6587\u4ef6\u6ca1\u6709\u90a3\u4e48\u6709\u4ef7\u503c\u3002\u89e3\u91ca BBB \u7684\u91cd\u8981\u6027\u6216\u751f\u7269\u7ed3\u6784\u7684\u6587\u4ef6\u662f\u4e0d\u76f8\u5173\u7684\uff0c\u5e76\u4e14\u57fa\u4e8e\u975e\u8102\u8d28\u7684\u8f7d\u4f53\u4e5f\u662f\u4e0d\u76f8\u5173\u7684\u3002"}]}
{"topic_id": "3", "languages_with_qrels": [], "topics": [{"lang": "eng", "source": "original", "topic_title": "metallicity of stars", "topic_description": "I'm looking for information on the metallicity of stars.", "topic_narrative": "Information about detailed studies on the metallicity of stars, for example, how the metallicity is measured or what is the metallicity of a star, is relevant. If the document only discusses the metallicity of stars in general, but does not elaborate on one specific target to measure or development of the method, it would be considered as somewhat valuable. If the document is about other studies that uses metallicity as a tool (ie, the main focus of the study is not metallicity), it would be considered as not valuable."}, {"lang": "zho", "source": "human translation", "topic_title": "\u6052\u661f\u7684\u91d1\u5c5e\u4e30\u5ea6", "topic_description": "\u672c\u641c\u7d22\u65e8\u5728\u67e5\u627e\u6709\u5173\u6052\u661f\u91d1\u5c5e\u4e30\u5ea6\u7684\u7814\u7a76\u5185\u5bb9\u3002", "topic_narrative": ""}, {"lang": "zho", "source": "google translation", "topic_title": "\u6052\u661f\u7684\u91d1\u5c5e\u4e30\u5ea6", "topic_description": "\u6211\u6b63\u5728\u5bfb\u627e\u6709\u5173\u6052\u661f\u91d1\u5c5e\u4e30\u5ea6\u7684\u4fe1\u606f\u3002", "topic_narrative": "\u5173\u4e8e\u6052\u661f\u91d1\u5c5e\u4e30\u5ea6\u7684\u8be6\u7ec6\u7814\u7a76\u7684\u4fe1\u606f\uff0c\u4f8b\u5982\uff0c\u5982\u4f55\u6d4b\u91cf\u91d1\u5c5e\u4e30\u5ea6\u6216\u6052\u661f\u7684\u91d1\u5c5e\u4e30\u5ea6\u662f\u4ec0\u4e48\uff0c\u662f\u76f8\u5173\u7684\u3002\u5982\u679c\u8be5\u6587\u4ef6\u4ec5\u603b\u4f53\u8ba8\u8bba\u6052\u661f\u7684\u91d1\u5c5e\u4e30\u5ea6\uff0c\u800c\u6ca1\u6709\u8be6\u7ec6\u8bf4\u660e\u8981\u6d4b\u91cf\u7684\u7279\u5b9a\u76ee\u6807\u6216\u8be5\u65b9\u6cd5\u7684\u5f00\u53d1\uff0c\u90a3\u4e48\u5b83\u5c06\u88ab\u8ba4\u4e3a\u5177\u6709\u4e00\u5b9a\u7684\u4ef7\u503c\u3002\u5982\u679c\u8be5\u6587\u4ef6\u662f\u5173\u4e8e\u4f7f\u7528\u91d1\u5c5e\u4e30\u5ea6\u4f5c\u4e3a\u5de5\u5177\u7684\u5176\u4ed6\u7814\u7a76\uff08\u5373\u7814\u7a76\u7684\u4e3b\u8981\u7126\u70b9\u4e0d\u662f\u91d1\u5c5e\u4e30\u5ea6\uff09\uff0c\u5b83\u5c06\u88ab\u8ba4\u4e3a\u6ca1\u6709\u4ef7\u503c\u3002"}]}
{"topic_id": "4", "languages_with_qrels": [], "topics": [{"lang": "eng", "source": "original", "topic_title": "supramolecular nanomedicines in cancer diagnostics", "topic_description": "I'm looking for articles providing information of supramolecules in cancer diagnostics in vivo imaging.", "topic_narrative": "Only articles discussing development of supramolecular nanomedicine (e.g. Liposomes, polymer-drug conjugates, protein-based nanomaterials) for designing new targeted supramolecular theragnostic agents are considered as relevant. If the articles discusses the principles of supramolecular interactions including van der Waals, hydrophobic, hydrogen bond, etc. without mentioning the design of nanomedicine, they will not be considered as relevant. Besides, articles focus on pathological analysis of patents and techniques of clinical treatment for various cancer diagnosis, such as Magnetic Resonance Imaging (MRI) and Computed Tomography (CT) Scan will not consider as relevant."}, {"lang": "zho", "source": "human translation", "topic_title": "\u8d85\u5206\u5b50\u7eb3\u7c73\u836f\u7269\u5e94\u7528\u4e8e\u764c\u75c7\u6cbb\u7597", "topic_description": "\u6211\u60f3\u8981\u627e\u7684\u6587\u732e\u63d0\u4f9b\u8d85\u5206\u5b50\u7eb3\u7c73\u836f\u7269\u5e94\u7528\u4e8e\u764c\u75c7\u8bca\u65ad\u548c\u4f53\u5185\u6210\u50cf\u7684\u4fe1\u606f\u3002", "topic_narrative": ""}, {"lang": "zho", "source": "google translation", "topic_title": "\u8d85\u5206\u5b50\u7eb3\u7c73\u836f\u7269\u5728\u764c\u75c7\u8bca\u65ad\u4e2d\u7684\u5e94\u7528", "topic_description": "\u6211\u6b63\u5728\u5bfb\u627e\u63d0\u4f9b\u764c\u75c7\u4f53\u5185\u6210\u50cf\u8d85\u5206\u5b50\u4fe1\u606f\u7684\u6587\u7ae0\u3002", "topic_narrative": "\u53ea\u6709\u8ba8\u8bba\u7528\u4e8e\u8bbe\u8ba1\u65b0\u7684\u9776\u5411\u8d85\u5206\u5b50\u6cbb\u7597\u5242\u7684\u8d85\u5206\u5b50\u7eb3\u7c73\u533b\u5b66\uff08\u4f8b\u5982\u8102\u8d28\u4f53\u3001\u805a\u5408\u7269\u836f\u7269\u7f00\u5408\u7269\u3001\u57fa\u4e8e\u86cb\u767d\u8d28\u7684\u7eb3\u7c73\u6750\u6599\uff09\u7684\u5f00\u53d1\u7684\u6587\u7ae0\u624d\u88ab\u8ba4\u4e3a\u662f\u76f8\u5173\u7684\u3002\u5982\u679c\u6587\u7ae0\u8ba8\u8bba\u8d85\u5206\u5b50\u76f8\u4e92\u4f5c\u7528\u7684\u539f\u7406\uff0c\u5305\u62ec\u8303\u5fb7\u534e\u3001\u758f\u6c34\u3001\u6c22\u952e\u7b49\uff0c\u4f46\u6ca1\u6709\u63d0\u53ca\u7eb3\u7c73\u533b\u5b66\u7684\u8bbe\u8ba1\uff0c\u5219\u4e0d\u4f1a\u88ab\u8ba4\u4e3a\u662f\u76f8\u5173\u7684\u3002\u6b64\u5916\uff0c\u6587\u7ae0\u4fa7\u91cd\u4e8e\u5404\u79cd\u764c\u75c7\u8bca\u65ad\u7684\u4e13\u5229\u548c\u4e34\u5e8a\u6cbb\u7597\u6280\u672f\u7684\u75c5\u7406\u5206\u6790\uff0c\u4f8b\u5982\u78c1\u5171\u632f\u6210\u50cf\uff08MRI\uff09\u548c\u8ba1\u7b97\u673a\u65ad\u5c42\u626b\u63cf\uff08CT\uff09\u626b\u63cf\u5c06\u4e0d\u88ab\u89c6\u4e3a\u76f8\u5173\u3002"}]}
{"topic_id": "5", "languages_with_qrels": [], "topics": [{"lang": "eng", "source": "original", "topic_title": "Beijing electron positron collider detector", "topic_description": "I'm searching for studies on the detector design of the Beijing Electron-Positron Collider II (BEPCII).", "topic_narrative": "Information on detector studies of the Beijing Electron-Positron Collider II (BEPCII) is relevant. If the article discusses the design or hardware components of BEPCII, but does not include information on detecting, it would be considered somewhat valuable. If the article discusses a specific detector design, but does not mention the electron positron collider, it would be considered irrelevant. Additionally, if the article mainly discusses the software component of the BEPCII, it would be considered as irrelevant."}, {"lang": "zho", "source": "human translation", "topic_title": "\u5317\u4eac\u6b63\u8d1f\u7535\u5b50\u5bf9\u649e\u673a\u63a2\u6d4b\u5668", "topic_description": "\u672c\u641c\u7d22\u65e8\u5728\u67e5\u627e\u6709\u5173\u5317\u4eac\u6b63\u8d1f\u7535\u5b50\u5bf9\u649e\u673a\u63a2\u6d4b\u5668\u8bbe\u8ba1\u7684\u76f8\u5173\u7814\u7a76\u3002", "topic_narrative": ""}, {"lang": "zho", "source": "google translation", "topic_title": "\u5317\u4eac\u6b63\u8d1f\u7535\u5b50\u5bf9\u649e\u673a\u63a2\u6d4b\u5668", "topic_description": "\u6211\u6b63\u5728\u5bfb\u627e\u6709\u5173\u5317\u4eac\u6b63\u8d1f\u7535\u5b50\u5bf9\u649e\u673a II (BEPCII) \u63a2\u6d4b\u5668\u8bbe\u8ba1\u7684\u7814\u7a76\u3002", "topic_narrative": "\u6709\u5173\u5317\u4eac\u6b63\u8d1f\u7535\u5b50\u5bf9\u649e\u673a II (BEPCII) \u63a2\u6d4b\u5668\u7814\u7a76\u7684\u4fe1\u606f\u662f\u76f8\u5173\u7684\u3002\u5982\u679c\u6587\u7ae0\u8ba8\u8bba\u4e86BEPCII\u7684\u8bbe\u8ba1\u6216\u786c\u4ef6\u7ec4\u4ef6\uff0c\u4f46\u4e0d\u5305\u62ec\u68c0\u6d4b\u4fe1\u606f\uff0c\u90a3\u4e48\u5b83\u5c06\u88ab\u8ba4\u4e3a\u662f\u6709\u4ef7\u503c\u7684\u3002\u5982\u679c\u6587\u7ae0\u8ba8\u8bba\u4e86\u5177\u4f53\u7684\u63a2\u6d4b\u5668\u8bbe\u8ba1\uff0c\u4f46\u6ca1\u6709\u63d0\u53ca\u6b63\u8d1f\u7535\u5b50\u5bf9\u649e\u673a\uff0c\u5219\u4f1a\u88ab\u8ba4\u4e3a\u65e0\u5173\u7d27\u8981\u3002\u53e6\u5916\uff0c\u5982\u679c\u6587\u7ae0\u4e3b\u8981\u8ba8\u8bbaBEPCII\u7684\u8f6f\u4ef6\u7ec4\u4ef6\uff0c\u90a3\u4e48\u5b83\u4f1a\u88ab\u8ba4\u4e3a\u662f\u65e0\u5173\u7d27\u8981\u7684\u3002"}]}
{"topic_id": "6", "languages_with_qrels": [], "topics": [{"lang": "eng", "source": "original", "topic_title": "RT-PCR DNA Colony bacterials", "topic_description": "How RT-PCR is used to transfer DNA into bacterials?", "topic_narrative": "PCR is used to duplicate DNA by changing the temperature of the process with necessary ingredients including enzymes and nucleotides. Relevant documents will describe how RT-PCR is to transfer DNA into bacterials. Using RT-PCR to transfer DNA to any other type of cell other than bacertials will be considered not relevant."}, {"lang": "zho", "source": "human translation", "topic_title": "\u53cd\u8f6c\u5f55\u805a\u5408\u9176\u94fe\u53cd\u5e94 \u7ec6\u83cc \u514b\u9686", "topic_description": "\u53cd\u8f6c\u5f55\u805a\u5408\u9176\u53cd\u5e94\u662f\u5982\u4f55\u5c06\u9057\u4f20\u7269\u8d28\u8f6c\u5165\u5230\u7ec6\u83cc\u4e2d\u7684\uff1f", "topic_narrative": ""}, {"lang": "zho", "source": "google translation", "topic_title": "RT-PCR DNA \u83cc\u843d\u7ec6\u83cc", "topic_description": "\u5982\u4f55\u4f7f\u7528 RT-PCR \u5c06 DNA \u8f6c\u79fb\u5230\u7ec6\u83cc\u4e2d\uff1f", "topic_narrative": "PCR \u7528\u4e8e\u901a\u8fc7\u6539\u53d8\u8fc7\u7a0b\u6e29\u5ea6\u4ee5\u53ca\u9176\u548c\u6838\u82f7\u9178\u7b49\u5fc5\u8981\u6210\u5206\u6765\u590d\u5236 DNA\u3002\u76f8\u5173\u6587\u732e\u5c06\u63cf\u8ff0RT-PCR\u5982\u4f55\u5c06DNA\u8f6c\u79fb\u5230\u7ec6\u83cc\u4e2d\u3002\u4f7f\u7528 RT-PCR \u5c06 DNA \u8f6c\u79fb\u81f3\u7ec6\u83cc\u4ee5\u5916\u7684\u4efb\u4f55\u5176\u4ed6\u7c7b\u578b\u7684\u7ec6\u80de\u5c06\u88ab\u89c6\u4e3a\u4e0d\u76f8\u5173\u3002"}]}
{"topic_id": "7", "languages_with_qrels": [], "topics": [{"lang": "eng", "source": "original", "topic_title": "mass spectroscopy fragment", "topic_description": "What methods do researchers use to detect unknown molecular mass?", "topic_narrative": "A relevant document will describe an instance where mass spectroscopy was used over several fragments. if mass spectroscopy was involved, but the measurant was not taken over a series of fragments, the article would be considered not relevant. Only when the artical describes one mass spectroscopy with fragments and its aimed prodcut, it should be considered as relevant artical."}, {"lang": "zho", "source": "human translation", "topic_title": "\u8d28\u8c31 \u788e\u7247", "topic_description": "\u7814\u7a76\u4eba\u5458\u7528\u4ec0\u4e48\u53bb\u6d4b\u91cf\u672a\u77e5\u7269\u8d28\u7684\u8d28\u91cf\uff1f", "topic_narrative": ""}, {"lang": "zho", "source": "google translation", "topic_title": "\u8d28\u8c31\u7247\u6bb5", "topic_description": "\u7814\u7a76\u4eba\u5458\u4f7f\u7528\u4ec0\u4e48\u65b9\u6cd5\u6765\u68c0\u6d4b\u672a\u77e5\u7684\u5206\u5b50\u8d28\u91cf\uff1f", "topic_narrative": "\u76f8\u5173\u6587\u4ef6\u5c06\u63cf\u8ff0\u5bf9\u591a\u4e2a\u7247\u6bb5\u4f7f\u7528\u8d28\u8c31\u5206\u6790\u7684\u5b9e\u4f8b\u3002\u5982\u679c\u6d89\u53ca\u8d28\u8c31\uff0c\u4f46\u6d4b\u91cf\u5bf9\u8c61\u4e0d\u662f\u4e00\u7cfb\u5217\u7247\u6bb5\uff0c\u5219\u8be5\u6587\u7ae0\u5c06\u88ab\u8ba4\u4e3a\u4e0d\u76f8\u5173\u3002\u53ea\u6709\u5f53\u6587\u7ae0\u63cf\u8ff0\u4e86\u4e00\u79cd\u5e26\u6709\u7247\u6bb5\u7684\u8d28\u8c31\u53ca\u5176\u76ee\u6807\u4ea7\u54c1\u65f6\uff0c\u624d\u5e94\u88ab\u89c6\u4e3a\u76f8\u5173\u6587\u7ae0\u3002"}]}
{"topic_id": "8", "languages_with_qrels": [], "topics": [{"lang": "eng", "source": "original", "topic_title": "drug application of LNP carrying mRNA", "topic_description": "I am looking for information that introduces how lipid nanoparticles (LNP) carry message RNA (mRNA) and examples that can help explain their importance and potential in drug applications.", "topic_narrative": "Relevant documents describe research progress on mRNA-carrying LNP or nucleotides-carrying LNP that can help explain their importance and potential in drug applications. Other lipid-based carriers carrying mRNA, such as solid lipid nanoparticles are also relevant. Nucleotides other than mRNA delivery are also relevant, but would be considered somewhat valuable. Non-lipid based vectors are irrelevant and lipid-based vectors that are not carrying nucleotides are irrelevant. Documents that described research using mRNA to cure diseases are irrelevant as the focus needs to be on delivery vectors."}, {"lang": "zho", "source": "human translation", "topic_title": "\u643a\u5e26mRNA\u7684\u8102\u8d28\u7eb3\u7c73\u9897\u7c92\u8f7d\u4f53\u7684\u836f\u7269\u5e94\u7528", "topic_description": "\u6211\u60f3\u5bfb\u627e\u5173\u4e8e\u643a\u5e26\u4fe1\u53f7RNA\u7684\u8102\u8d28\u7eb3\u7c73\u9897\u7c92\u8f7d\u4f53\u7684\u80fd\u8868\u73b0\u5176\u5728\u836f\u7269\u5e94\u7528\u4e0a\u91cd\u8981\u6027\u548c\u6f5c\u529b\u7684\u4fe1\u606f\u3002", "topic_narrative": ""}, {"lang": "zho", "source": "google translation", "topic_title": "\u643a\u5e26mRNA\u7684LNP\u7684\u836f\u7269\u5e94\u7528", "topic_description": "\u6211\u6b63\u5728\u5bfb\u627e\u4ecb\u7ecd\u8102\u8d28\u7eb3\u7c73\u9897\u7c92 (LNP) \u5982\u4f55\u643a\u5e26\u4fe1\u606f RNA (mRNA) \u7684\u4fe1\u606f\u4ee5\u53ca\u6709\u52a9\u4e8e\u89e3\u91ca\u5176\u5728\u836f\u7269\u5e94\u7528\u4e2d\u7684\u91cd\u8981\u6027\u548c\u6f5c\u529b\u7684\u793a\u4f8b\u3002", "topic_narrative": "\u76f8\u5173\u6587\u732e\u63cf\u8ff0\u4e86\u643a\u5e26mRNA\u7684LNP\u6216\u643a\u5e26\u6838\u82f7\u9178\u7684LNP\u7684\u7814\u7a76\u8fdb\u5c55\uff0c\u6709\u52a9\u4e8e\u89e3\u91ca\u5b83\u4eec\u5728\u836f\u7269\u5e94\u7528\u4e2d\u7684\u91cd\u8981\u6027\u548c\u6f5c\u529b\u3002\u5176\u4ed6\u643a\u5e26 mRNA \u7684\u8102\u8d28\u8f7d\u4f53\uff0c\u4f8b\u5982\u56fa\u4f53\u8102\u8d28\u7eb3\u7c73\u9897\u7c92\u4e5f\u76f8\u5173\u3002\u9664 mRNA \u9012\u9001\u5916\u7684\u6838\u82f7\u9178\u4e5f\u76f8\u5173\uff0c\u4f46\u88ab\u8ba4\u4e3a\u5177\u6709\u4e00\u5b9a\u4ef7\u503c\u3002\u57fa\u4e8e\u975e\u8102\u8d28\u7684\u8f7d\u4f53\u662f\u4e0d\u76f8\u5173\u7684\uff0c\u5e76\u4e14\u4e0d\u643a\u5e26\u6838\u82f7\u9178\u7684\u57fa\u4e8e\u8102\u8d28\u7684\u8f7d\u4f53\u662f\u4e0d\u76f8\u5173\u7684\u3002\u63cf\u8ff0\u4f7f\u7528 mRNA \u6cbb\u7597\u75be\u75c5\u7684\u7814\u7a76\u7684\u6587\u4ef6\u662f\u65e0\u5173\u7d27\u8981\u7684\uff0c\u56e0\u4e3a\u91cd\u70b9\u9700\u8981\u653e\u5728\u9012\u9001\u8f7d\u4f53\u4e0a\u3002"}]}
{"topic_id": "9", "languages_with_qrels": [], "topics": [{"lang": "eng", "source": "original", "topic_title": "Mechanism of cellular senescence", "topic_description": "I want to find articles that talk about the biological mechanisms underlying cellular senescence.", "topic_narrative": "Articles about the biological mechanisms underlying cellular senescence, such as signaling pathways and cellular behaviors that are characteristic in senescent cells are considered relevant. Articles about any other cellular process that are not senescence will not be considered relevant. Cell death pathways, such as apoptosis and necrosis which are similar to senescence are not relevant unless they are linked to cellular senescence."}, {"lang": "zho", "source": "human translation", "topic_title": "\u7ec6\u80de\u8870\u8001\u673a\u5236", "topic_description": "\u6211\u5e0c\u671b\u627e\u5230\u5173\u4e8e\u7ec6\u80de\u8870\u8001\u7684\u751f\u7269\u5b66\u673a\u5236\u7684\u6587\u7ae0\u3002", "topic_narrative": ""}, {"lang": "zho", "source": "google translation", "topic_title": "\u7ec6\u80de\u8870\u8001\u673a\u5236", "topic_description": "\u6211\u60f3\u627e\u5230\u8c08\u8bba\u7ec6\u80de\u8870\u8001\u7684\u751f\u7269\u5b66\u673a\u5236\u7684\u6587\u7ae0\u3002", "topic_narrative": "\u5173\u4e8e\u7ec6\u80de\u8870\u8001\u7684\u751f\u7269\u5b66\u673a\u5236\u7684\u6587\u7ae0\uff0c\u4f8b\u5982\u8870\u8001\u7ec6\u80de\u7279\u6709\u7684\u4fe1\u53f7\u901a\u8def\u548c\u7ec6\u80de\u884c\u4e3a\uff0c\u88ab\u8ba4\u4e3a\u662f\u76f8\u5173\u7684\u3002\u6709\u5173\u975e\u8870\u8001\u7684\u4efb\u4f55\u5176\u4ed6\u7ec6\u80de\u8fc7\u7a0b\u7684\u6587\u7ae0\u5c06\u4e0d\u88ab\u89c6\u4e3a\u76f8\u5173\u3002\u7ec6\u80de\u6b7b\u4ea1\u9014\u5f84\uff0c\u4f8b\u5982\u4e0e\u8870\u8001\u76f8\u4f3c\u7684\u7ec6\u80de\u51cb\u4ea1\u548c\u574f\u6b7b\uff0c\u9664\u975e\u4e0e\u7ec6\u80de\u8870\u8001\u76f8\u5173\uff0c\u5426\u5219\u65e0\u5173\u7d27\u8981\u3002"}]}
{"topic_id": "10", "languages_with_qrels": [], "topics": [{"lang": "eng", "source": "original", "topic_title": "Internet improve rural economy", "topic_description": "How does Internet availability improve the rural economy?", "topic_narrative": "Relevant articles should focus on the process of Internet availability contributing to the rural economy, but not on the result that what the government should do to utilize the Internet to improve the rural economy. Focusing on the influence on the city economy is also deemed irrelevant. Documents talking about how technology/ some specific components of the Internet improves the rural economy/urbanization would be considered somewhat valuable."}, {"lang": "zho", "source": "human translation", "topic_title": "\u4e92\u8054\u7f51 \u63d0\u5347 \u4e61\u6751\u7684 \u7ecf\u6d4e", "topic_description": "\u4e92\u8054\u7f51\u666e\u53ca\u5982\u4f55\u63d0\u5347\u4e61\u6751\u7ecf\u6d4e\uff1f", "topic_narrative": ""}, {"lang": "zho", "source": "google translation", "topic_title": "\u4e92\u8054\u7f51\u5e26\u52a8\u519c\u6751\u7ecf\u6d4e", "topic_description": "\u4e92\u8054\u7f51\u7684\u666e\u53ca\u5982\u4f55\u6539\u5584\u519c\u6751\u7ecf\u6d4e\uff1f", "topic_narrative": "\u76f8\u5173\u6587\u7ae0\u5e94\u8be5\u5173\u6ce8\u4e92\u8054\u7f51\u5bf9\u519c\u6751\u7ecf\u6d4e\u7684\u8d21\u732e\u8fc7\u7a0b\uff0c\u800c\u4e0d\u662f\u653f\u5e9c\u5e94\u8be5\u5982\u4f55\u5229\u7528\u4e92\u8054\u7f51\u6765\u6539\u5584\u519c\u6751\u7ecf\u6d4e\u7684\u7ed3\u679c\u3002\u5173\u6ce8\u5bf9\u57ce\u5e02\u7ecf\u6d4e\u7684\u5f71\u54cd\u4e5f\u88ab\u8ba4\u4e3a\u662f\u65e0\u5173\u7d27\u8981\u7684\u3002\u8ba8\u8bba\u6280\u672f/\u4e92\u8054\u7f51\u7684\u67d0\u4e9b\u7279\u5b9a\u7ec4\u6210\u90e8\u5206\u5982\u4f55\u6539\u5584\u519c\u6751\u7ecf\u6d4e/\u57ce\u5e02\u5316\u7684\u6587\u4ef6\u5c06\u88ab\u8ba4\u4e3a\u662f\u6709\u4ef7\u503c\u7684\u3002"}]}
{"topic_id": "11", "languages_with_qrels": [], "topics": [{"lang": "eng", "source": "original", "topic_title": "The meiosis", "topic_description": "I wish to find articles pertaining to the biological process of meiosis.", "topic_narrative": "Articles related to meiosis, which is an essential step in gametogenesis, are relevant. Any article that includes information on meiosis would be considered relevant, wether it is a general broad overview of the process or any research discovering new aspects regarding the process. Any article talking about this process would be considered relevant. However, articles on a different topic that mention meiosis as an example would be considered central but that not valuable."}, {"lang": "zho", "source": "human translation", "topic_title": "\u51cf\u6570\u5206\u88c2", "topic_description": "\u6211\u5e0c\u671b\u627e\u5230\u5173\u4e8e\u51cf\u6570\u5206\u88c2\u7684\u7814\u7a76\u6587\u7ae0\u3002", "topic_narrative": ""}, {"lang": "zho", "source": "google translation", "topic_title": "\u51cf\u6570\u5206\u88c2", "topic_description": "\u6211\u5e0c\u671b\u627e\u5230\u6709\u5173\u51cf\u6570\u5206\u88c2\u751f\u7269\u8fc7\u7a0b\u7684\u6587\u7ae0\u3002", "topic_narrative": "\u4e0e\u51cf\u6570\u5206\u88c2\u76f8\u5173\u7684\u6587\u7ae0\u662f\u76f8\u5173\u7684\uff0c\u51cf\u6570\u5206\u88c2\u662f\u914d\u5b50\u53d1\u751f\u7684\u91cd\u8981\u6b65\u9aa4\u3002\u4efb\u4f55\u5305\u542b\u6709\u5173\u51cf\u6570\u5206\u88c2\u4fe1\u606f\u7684\u6587\u7ae0\u90fd\u5c06\u88ab\u8ba4\u4e3a\u662f\u76f8\u5173\u7684\uff0c\u65e0\u8bba\u662f\u5bf9\u8be5\u8fc7\u7a0b\u7684\u603b\u4f53\u6982\u8ff0\u8fd8\u662f\u53d1\u73b0\u6709\u5173\u8be5\u8fc7\u7a0b\u7684\u65b0\u65b9\u9762\u7684\u4efb\u4f55\u7814\u7a76\u3002\u4efb\u4f55\u8ba8\u8bba\u6b64\u8fc7\u7a0b\u7684\u6587\u7ae0\u90fd\u5c06\u88ab\u8ba4\u4e3a\u662f\u76f8\u5173\u7684\u3002\u7136\u800c\uff0c\u4ee5\u51cf\u6570\u5206\u88c2\u4e3a\u4f8b\u7684\u4e0d\u540c\u4e3b\u9898\u7684\u6587\u7ae0\u5c06\u88ab\u8ba4\u4e3a\u662f\u6838\u5fc3\u5185\u5bb9\uff0c\u4f46\u6ca1\u6709\u4ef7\u503c\u3002"}]}
{"topic_id": "12", "languages_with_qrels": [], "topics": [{"lang": "eng", "source": "original", "topic_title": "theoretical models of dark matter", "topic_description": "I'm looking for information on theoretical models of dark matter.", "topic_narrative": "Information on theoretically proposed models of dark matter is relevant. If the document only mentions \"dark matter\" or \"dark matter model\", but does not elaborate which model it is (e.g. WIMP model, CDM model, etc), it would be considered somewhat valuable. If the document only mentions \"dark energy model\", it would be considered not valuable."}, {"lang": "zho", "source": "human translation", "topic_title": "\u6697\u7269\u8d28\u7684\u7406\u8bba\u6a21\u578b", "topic_description": "\u672c\u641c\u7d22\u65e8\u5728\u67e5\u627e\u6709\u5173\u6697\u7269\u8d28\u7684\u7406\u8bba\u6a21\u578b\u7684\u4fe1\u606f\u3002", "topic_narrative": ""}, {"lang": "zho", "source": "google translation", "topic_title": "\u6697\u7269\u8d28\u7684\u7406\u8bba\u6a21\u578b", "topic_description": "\u6211\u6b63\u5728\u5bfb\u627e\u6709\u5173\u6697\u7269\u8d28\u7406\u8bba\u6a21\u578b\u7684\u4fe1\u606f\u3002", "topic_narrative": "\u6709\u5173\u7406\u8bba\u4e0a\u63d0\u51fa\u7684\u6697\u7269\u8d28\u6a21\u578b\u7684\u4fe1\u606f\u662f\u76f8\u5173\u7684\u3002\u5982\u679c\u6587\u4ef6\u53ea\u63d0\u5230\u201c\u6697\u7269\u8d28\u201d\u6216\u201c\u6697\u7269\u8d28\u6a21\u578b\u201d\uff0c\u4f46\u6ca1\u6709\u8be6\u7ec6\u8bf4\u660e\u5b83\u662f\u4ec0\u4e48\u6a21\u578b\uff08\u4f8b\u5982WIMP\u6a21\u578b\u3001CDM\u6a21\u578b\u7b49\uff09\uff0c\u90a3\u4e48\u5b83\u4f1a\u88ab\u8ba4\u4e3a\u6709\u4e00\u5b9a\u7684\u4ef7\u503c\u3002\u5982\u679c\u6587\u4ef6\u4e2d\u53ea\u63d0\u5230\u201c\u6697\u80fd\u91cf\u6a21\u578b\u201d\uff0c\u5c31\u4f1a\u88ab\u8ba4\u4e3a\u6ca1\u6709\u4ef7\u503c\u3002"}]}
{"topic_id": "13", "languages_with_qrels": [], "topics": [{"lang": "eng", "source": "original", "topic_title": "sub-prime crisis Chinese financial market", "topic_description": "I am looking for information about the influence of the sub-prime crisis on Chinese financial market.", "topic_narrative": "Relevant articles should contain information talking about how the U.S. subprime crisis directly or indirectly influence the financial market in China. The influence can be about some specific prospectives. Articles that do not include information concerning the Chinese financial market are considered irrelevant. If the article only brings up how China can learn from the subprime crisis, it is not considered relevant."}, {"lang": "zho", "source": "human translation", "topic_title": "\u6b21\u8d37 \u5371\u673a \u4e2d\u56fd\u7684 \u91d1\u878d \u5e02\u573a", "topic_description": "\u6211\u60f3\u67e5\u627e\u6709\u5173\u6b21\u8d37\u5371\u673a\u5bf9\u4e8e\u4e2d\u56fd\u91d1\u878d\u5e02\u573a\u5f71\u54cd\u7684\u8d44\u6599\u3002", "topic_narrative": ""}, {"lang": "zho", "source": "google translation", "topic_title": "\u6b21\u8d37\u5371\u673a\u4e2d\u56fd\u91d1\u878d\u5e02\u573a", "topic_description": "\u6211\u6b63\u5728\u5bfb\u627e\u6709\u5173\u6b21\u8d37\u5371\u673a\u5bf9\u4e2d\u56fd\u91d1\u878d\u5e02\u573a\u5f71\u54cd\u7684\u4fe1\u606f\u3002", "topic_narrative": "\u76f8\u5173\u6587\u7ae0\u5e94\u5305\u542b\u7f8e\u56fd\u6b21\u8d37\u5371\u673a\u5982\u4f55\u76f4\u63a5\u6216\u95f4\u63a5\u5f71\u54cd\u4e2d\u56fd\u91d1\u878d\u5e02\u573a\u7684\u4fe1\u606f\u3002\u5f71\u54cd\u53ef\u80fd\u4e0e\u67d0\u4e9b\u7279\u5b9a\u7684\u524d\u666f\u6709\u5173\u3002\u4e0d\u5305\u542b\u6709\u5173\u4e2d\u56fd\u91d1\u878d\u5e02\u573a\u4fe1\u606f\u7684\u6587\u7ae0\u88ab\u89c6\u4e3a\u65e0\u5173\u7d27\u8981\u3002\u5982\u679c\u8fd9\u7bc7\u6587\u7ae0\u53ea\u662f\u63d0\u51fa\u4e2d\u56fd\u5982\u4f55\u4ece\u6b21\u8d37\u5371\u673a\u4e2d\u5438\u53d6\u6559\u8bad\uff0c\u90a3\u4e48\u5b83\u5c31\u4e0d\u88ab\u8ba4\u4e3a\u662f\u76f8\u5173\u7684\u3002"}]}
{"topic_id": "14", "languages_with_qrels": [], "topics": [{"lang": "eng", "source": "original", "topic_title": "RNA-carrying viral drug delivery", "topic_description": "I am looking for information for progress on viral drug delivery vectors that carry RNA as cargo to cure disease.", "topic_narrative": "Documents that discuss research progress on mRNA-carrying viral vectors and documents on mRNA-carrying or siRNA-carrying viral vectors that can help explain their importance and potential in drug application. Protocols to make viral vectors and methods to evaluate its efficiency, or articles about nanomedicine are irrelevant. Non-viral based vectors are irrelevant and viral-based vectors not carrying nucleotides are irrelevant."}, {"lang": "zho", "source": "human translation", "topic_title": "\u643a\u5e26RNA\u7684\u75c5\u6bd2\u836f\u7269\u9012\u9001\u8f7d\u4f53", "topic_description": "\u6211\u60f3\u5bfb\u627e\u5173\u4e8e\u4f7f\u7528\u75c5\u6bd2\u836f\u7269\u9012\u9001\u8f7d\u4f53\u643a\u5e26RNA\u5206\u5b50\u8fdb\u884c\u75be\u75c5\u6cbb\u7597\u7684\u76f8\u5173\u4fe1\u606f\u3002", "topic_narrative": ""}, {"lang": "zho", "source": "google translation", "topic_title": "\u643a\u5e26RNA\u7684\u75c5\u6bd2\u836f\u7269\u9012\u9001", "topic_description": "\u6211\u6b63\u5728\u5bfb\u627e\u6709\u5173\u643a\u5e26 RNA \u4f5c\u4e3a\u8d27\u7269\u6765\u6cbb\u7597\u75be\u75c5\u7684\u75c5\u6bd2\u836f\u7269\u9012\u9001\u8f7d\u4f53\u8fdb\u5c55\u7684\u4fe1\u606f\u3002", "topic_narrative": "\u8ba8\u8bba\u643a\u5e26 mRNA \u7684\u75c5\u6bd2\u8f7d\u4f53\u7684\u7814\u7a76\u8fdb\u5c55\u7684\u6587\u732e\uff0c\u4ee5\u53ca\u643a\u5e26 mRNA \u6216\u643a\u5e26 siRNA \u7684\u75c5\u6bd2\u8f7d\u4f53\u7684\u6587\u732e\uff0c\u6709\u52a9\u4e8e\u89e3\u91ca\u5176\u5728\u836f\u7269\u5e94\u7528\u4e2d\u7684\u91cd\u8981\u6027\u548c\u6f5c\u529b\u3002\u5236\u4f5c\u75c5\u6bd2\u8f7d\u4f53\u7684\u65b9\u6848\u548c\u8bc4\u4f30\u5176\u6548\u7387\u7684\u65b9\u6cd5\uff0c\u6216\u6709\u5173\u7eb3\u7c73\u533b\u5b66\u7684\u6587\u7ae0\u90fd\u662f\u65e0\u5173\u7d27\u8981\u7684\u3002\u57fa\u4e8e\u975e\u75c5\u6bd2\u7684\u8f7d\u4f53\u662f\u4e0d\u76f8\u5173\u7684\uff0c\u5e76\u4e14\u4e0d\u643a\u5e26\u6838\u82f7\u9178\u7684\u57fa\u4e8e\u75c5\u6bd2\u7684\u8f7d\u4f53\u662f\u4e0d\u76f8\u5173\u7684\u3002"}]}
{"topic_id": "15", "languages_with_qrels": [], "topics": [{"lang": "eng", "source": "original", "topic_title": "PCR principle, its function in the lab", "topic_description": "What is PCR reaction and how does it work?", "topic_narrative": "A relevant article will describe the usefulness of the PCR technique for quickly duplicating DNA for a colony. An article is not relevant if it uses the PCR technique for something besides DNA duliplcation for a colony. An article is also not relevant if does not describe the speed of the PCR technique. Only when the artical describes the duplication of DNA, it is a relevant artical."}, {"lang": "zho", "source": "human translation", "topic_title": "\u9176\u94fe\u5f0f\u53cd\u5e94\u7684\u539f\u7406 \u5176\u5728\u5b9e\u9a8c\u5ba4\u4e2d\u7684\u5e94\u7528", "topic_description": "\u4ec0\u4e48\u662f\u9176\u94fe\u5f0f\u53cd\u5e94\u4ee5\u53ca\u5176\u5982\u4f55\u5de5\u4f5c\uff1f", "topic_narrative": ""}, {"lang": "zho", "source": "google translation", "topic_title": "PCR\u539f\u7406\u53ca\u5176\u5728\u5b9e\u9a8c\u5ba4\u4e2d\u7684\u4f5c\u7528", "topic_description": "\u4ec0\u4e48\u662f PCR \u53cd\u5e94\u53ca\u5176\u5de5\u4f5c\u539f\u7406\uff1f", "topic_narrative": "\u4e00\u7bc7\u76f8\u5173\u6587\u7ae0\u5c06\u63cf\u8ff0 PCR \u6280\u672f\u5728\u5feb\u901f\u590d\u5236\u83cc\u843d DNA \u65b9\u9762\u7684\u7528\u9014\u3002\u5982\u679c\u4e00\u7bc7\u6587\u7ae0\u5c06 PCR \u6280\u672f\u7528\u4e8e\u83cc\u843d DNA \u590d\u5236\u4e4b\u5916\u7684\u5176\u4ed6\u7528\u9014\uff0c\u5219\u8be5\u6587\u7ae0\u662f\u4e0d\u76f8\u5173\u7684\u3002\u5982\u679c\u4e00\u7bc7\u6587\u7ae0\u6ca1\u6709\u63cf\u8ff0 PCR \u6280\u672f\u7684\u901f\u5ea6\uff0c\u90a3\u4e48\u5b83\u4e5f\u662f\u6ca1\u6709\u610f\u4e49\u7684\u3002\u53ea\u6709\u5f53\u6587\u7ae0\u63cf\u8ff0\u4e86 DNA \u7684\u590d\u5236\u65f6\uff0c\u5b83\u624d\u662f\u76f8\u5173\u7684\u6587\u7ae0\u3002"}]}
{"topic_id": "16", "languages_with_qrels": [], "topics": [{"lang": "eng", "source": "original", "topic_title": "credit structure evolution trend", "topic_description": "I am looking for articles talking about the evolution and trends of credit structure in finance.", "topic_narrative": "The credit structure refers to the financial field. Articles mentioning both evolution and trends, or either of them are considered relevant. Talking about regional credit structure is also considered relevant. Articles talking about other structures or the credit system are irrelevant."}, {"lang": "zho", "source": "human translation", "topic_title": "\u4fe1\u8d37 \u7ed3\u6784 \u6f14\u53d8 \u8d8b\u52bf ", "topic_description": "\u6211\u8981\u67e5\u627e\u6709\u5173\u4fe1\u8d37\u7ed3\u6784\u7684\u6f14\u53d8\u548c\u8d8b\u52bf\u7684\u6587\u7ae0\u3002", "topic_narrative": ""}, {"lang": "zho", "source": "google translation", "topic_title": "\u4fe1\u8d37\u7ed3\u6784\u6f14\u53d8\u8d8b\u52bf", "topic_description": "\u6211\u6b63\u5728\u5bfb\u627e\u6709\u5173\u91d1\u878d\u4fe1\u8d37\u7ed3\u6784\u7684\u6f14\u53d8\u548c\u8d8b\u52bf\u7684\u6587\u7ae0\u3002", "topic_narrative": "\u4fe1\u8d37\u7ed3\u6784\u662f\u6307\u91d1\u878d\u9886\u57df\u3002\u540c\u65f6\u63d0\u53ca\u6f14\u53d8\u548c\u8d8b\u52bf\u6216\u5176\u4e2d\u4efb\u4f55\u4e00\u4e2a\u7684\u6587\u7ae0\u88ab\u8ba4\u4e3a\u662f\u76f8\u5173\u7684\u3002\u8c08\u8bba\u533a\u57df\u4fe1\u8d37\u7ed3\u6784\u4e5f\u88ab\u8ba4\u4e3a\u662f\u76f8\u5173\u7684\u3002\u8c08\u8bba\u5176\u4ed6\u7ed3\u6784\u6216\u4fe1\u7528\u4f53\u7cfb\u7684\u6587\u7ae0\u662f\u65e0\u5173\u7d27\u8981\u7684\u3002"}]}
{"topic_id": "17", "languages_with_qrels": [], "topics": [{"lang": "eng", "source": "original", "topic_title": "investor sentiment influence stock", "topic_description": "I am looking for how the investor sentiments influence the stock market.", "topic_narrative": "Relevant articles should include both the specific investor sentiments that would affect the market and how the influence mechanism works. However, articles talking about how the stock market affect the investor sentiment are considered irrelevant."}, {"lang": "zho", "source": "human translation", "topic_title": "\u6d88\u8d39\u8005 \u60c5\u7eea \u80a1\u7968", "topic_description": "\u6295\u8d44\u8005\u60c5\u7eea\u5bf9\u4e8e\u80a1\u7968\u5e02\u573a\u7684\u5f71\u54cd\u7814\u7a76", "topic_narrative": ""}, {"lang": "zho", "source": "google translation", "topic_title": "\u6295\u8d44\u8005\u60c5\u7eea\u5f71\u54cd\u80a1\u7968", "topic_description": "\u6211\u6b63\u5728\u5bfb\u627e\u6295\u8d44\u8005\u60c5\u7eea\u5982\u4f55\u5f71\u54cd\u80a1\u5e02\u3002", "topic_narrative": "\u76f8\u5173\u6587\u7ae0\u5e94\u5305\u62ec\u5f71\u54cd\u5e02\u573a\u7684\u5177\u4f53\u6295\u8d44\u8005\u60c5\u7eea\u4ee5\u53ca\u5f71\u54cd\u673a\u5236\u5982\u4f55\u8fd0\u4f5c\u3002\u7136\u800c\uff0c\u8c08\u8bba\u80a1\u5e02\u5982\u4f55\u5f71\u54cd\u6295\u8d44\u8005\u60c5\u7eea\u7684\u6587\u7ae0\u88ab\u8ba4\u4e3a\u662f\u65e0\u5173\u7d27\u8981\u7684\u3002"}]}
{"topic_id": "18", "languages_with_qrels": [], "topics": [{"lang": "eng", "source": "original", "topic_title": "Drosophila melanogaster germline stem cell", "topic_description": "I wish to find articles about Drosophila melanogaster germline stem cell.", "topic_narrative": "I want to find articles about Drosophila melanogaster germline stem cells. The article can be about the behavior of this cell type, their functions, or their distinctive underlying cellular and molecular mechanisms. Articles about downstream progenies of the germline stem cells are also relevant, as these can be traced back to germline stem cells and can convey information about them indirectly. Articles about any species other than Drosophila melanogaster or about any cell type other than germline stem cells are irrelevant."}, {"lang": "zho", "source": "human translation", "topic_title": "\u679c\u8747\u751f\u6b96\u5e72\u7ec6\u80de", "topic_description": "\u6211\u5e0c\u671b\u627e\u5230\u5173\u4e8e\u679c\u8747\u751f\u6b96\u5e72\u7ec6\u80de\u7684\u6587\u7ae0\u3002", "topic_narrative": ""}, {"lang": "zho", "source": "google translation", "topic_title": "\u679c\u8747\u751f\u6b96\u5e72\u7ec6\u80de", "topic_description": "\u6211\u5e0c\u671b\u627e\u5230\u6709\u5173\u679c\u8747\u751f\u6b96\u5e72\u7ec6\u80de\u7684\u6587\u7ae0\u3002", "topic_narrative": "\u6211\u60f3\u627e\u5230\u6709\u5173\u679c\u8747\u751f\u6b96\u5e72\u7ec6\u80de\u7684\u6587\u7ae0\u3002\u8fd9\u7bc7\u6587\u7ae0\u53ef\u4ee5\u662f\u5173\u4e8e\u8fd9\u79cd\u7ec6\u80de\u7c7b\u578b\u7684\u884c\u4e3a\u3001\u5b83\u4eec\u7684\u529f\u80fd\u6216\u5176\u72ec\u7279\u7684\u6f5c\u5728\u7ec6\u80de\u548c\u5206\u5b50\u673a\u5236\u3002\u6709\u5173\u751f\u6b96\u5e72\u7ec6\u80de\u4e0b\u6e38\u540e\u4ee3\u7684\u6587\u7ae0\u4e5f\u5f88\u76f8\u5173\uff0c\u56e0\u4e3a\u8fd9\u4e9b\u6587\u7ae0\u53ef\u4ee5\u8ffd\u6eaf\u5230\u751f\u6b96\u5e72\u7ec6\u80de\uff0c\u5e76\u53ef\u4ee5\u95f4\u63a5\u4f20\u8fbe\u6709\u5173\u5b83\u4eec\u7684\u4fe1\u606f\u3002\u5173\u4e8e\u9664\u679c\u8747\u4ee5\u5916\u7684\u4efb\u4f55\u7269\u79cd\u6216\u9664\u751f\u6b96\u7cfb\u5e72\u7ec6\u80de\u4ee5\u5916\u7684\u4efb\u4f55\u7ec6\u80de\u7c7b\u578b\u7684\u6587\u7ae0\u90fd\u662f\u4e0d\u76f8\u5173\u7684\u3002"}]}
{"topic_id": "19", "languages_with_qrels": [], "topics": [{"lang": "eng", "source": "original", "topic_title": "reflux reaction condenser organic synthesis", "topic_description": "Under what circumstances do researchers need to use reflux reaction in organic sythesis?", "topic_narrative": "A relevant document will describe how a reflux reaction is used to in an organic synthesis experiment about raising the temperature of an experiment to keep solvent inside reaction. A non-relevant document will mention the process without speficing why it is used."}, {"lang": "zho", "source": "human translation", "topic_title": "\u56de\u6d41\u53cd\u5e94 \u51b7\u51dd\u5668 \u6709\u673a\u5408\u6210", "topic_description": "\u5728\u6709\u673a\u5408\u6210\u4e2d\uff0c\u4ec0\u4e48\u65f6\u5019\u7814\u7a76\u4eba\u5458\u9700\u8981\u7528\u5230\u51b7\u51dd\u56de\u6d41\u53cd\u5e94\uff1f", "topic_narrative": ""}, {"lang": "zho", "source": "google translation", "topic_title": "\u56de\u6d41\u53cd\u5e94\u51b7\u51dd\u5668\u6709\u673a\u5408\u6210", "topic_description": "\u6709\u673a\u5408\u6210\u4e2d\u4ec0\u4e48\u60c5\u51b5\u4e0b\u9700\u8981\u7528\u5230\u56de\u6d41\u53cd\u5e94\uff1f", "topic_narrative": "\u76f8\u5173\u6587\u732e\u5c06\u63cf\u8ff0\u5982\u4f55\u5728\u6709\u673a\u5408\u6210\u5b9e\u9a8c\u4e2d\u4f7f\u7528\u56de\u6d41\u53cd\u5e94\u6765\u63d0\u9ad8\u5b9e\u9a8c\u6e29\u5ea6\u4ee5\u4f7f\u6eb6\u5242\u4fdd\u6301\u5728\u53cd\u5e94\u5185\u90e8\u3002\u4e0d\u76f8\u5173\u7684\u6587\u6863\u5c06\u63d0\u53ca\u8be5\u8fc7\u7a0b\uff0c\u4f46\u4e0d\u4f1a\u5177\u4f53\u8bf4\u660e\u4e3a\u4ec0\u4e48\u4f7f\u7528\u5b83\u3002"}]}
{"topic_id": "20", "languages_with_qrels": [], "topics": [{"lang": "eng", "source": "original", "topic_title": "Drosophila melanogaster early stage oogenesis", "topic_description": "I want to find articles about early stage Drosophila melanogaster oogenesis process that happens in the germarium region.", "topic_narrative": "Articles that describe the early oogenesis process in the germarium region in Drosophila melanogaster are relevant. Articles about any other species or about later stages of oogenesis outside of the germarium region such as stage 2-14 are not relevant. Specifically if any cellular and molecular processes that take place during this early oogenesis are covered it would be considered very valuable, and overall observational description on the process would be considered somewhat valuable."}, {"lang": "zho", "source": "human translation", "topic_title": "\u679c\u8747\u65e9\u671f\u5375\u5b50\u53d1\u80b2", "topic_description": "\u6211\u5e0c\u671b\u627e\u5230\u5173\u4e8e\u679c\u8747\u5728\u539f\u5375\u533a\u7684\u65e9\u671f\u5375\u5b50\u53d1\u80b2\u76f8\u5173\u6587\u7ae0\u3002", "topic_narrative": ""}, {"lang": "zho", "source": "google translation", "topic_title": "\u679c\u8747\u65e9\u671f\u5375\u5b50\u53d1\u751f", "topic_description": "\u6211\u60f3\u627e\u5230\u6709\u5173\u53d1\u751f\u5728\u9517\u533a\u7684\u65e9\u671f\u679c\u8747\u5375\u5b50\u53d1\u751f\u8fc7\u7a0b\u7684\u6587\u7ae0\u3002", "topic_narrative": "\u63cf\u8ff0\u679c\u8747\u80da\u533a\u65e9\u671f\u5375\u5b50\u53d1\u751f\u8fc7\u7a0b\u7684\u6587\u7ae0\u662f\u76f8\u5173\u7684\u3002\u5173\u4e8e\u4efb\u4f55\u5176\u4ed6\u7269\u79cd\u6216\u5173\u4e8e\u751f\u6b96\u533a\u4e4b\u5916\u7684\u5375\u5b50\u53d1\u751f\u540e\u671f\uff08\u4f8b\u5982\u7b2c 2-14 \u9636\u6bb5\uff09\u7684\u6587\u7ae0\u4e0d\u76f8\u5173\u3002\u5177\u4f53\u6765\u8bf4\uff0c\u5982\u679c\u6db5\u76d6\u4e86\u65e9\u671f\u5375\u5b50\u53d1\u751f\u671f\u95f4\u53d1\u751f\u7684\u4efb\u4f55\u7ec6\u80de\u548c\u5206\u5b50\u8fc7\u7a0b\uff0c\u90a3\u4e48\u5b83\u5c06\u88ab\u8ba4\u4e3a\u975e\u5e38\u6709\u4ef7\u503c\uff0c\u5e76\u4e14\u5bf9\u8be5\u8fc7\u7a0b\u7684\u6574\u4f53\u89c2\u5bdf\u63cf\u8ff0\u5c06\u88ab\u8ba4\u4e3a\u6709\u4e9b\u6709\u4ef7\u503c\u3002"}]}
{"topic_id": "21", "languages_with_qrels": [], "topics": [{"lang": "eng", "source": "original", "topic_title": "hydrogel cell retention", "topic_description": "I am looking for articles that's related to hydrogel cell retention.", "topic_narrative": "I am looking for articles focusing on the cell retention ability of certain types of hydrogels when hydrogels are are mixed with cells. A relevant documents must discuss both the hydrogel and the cell. A document that discusses one without the other would not be considered relevant. In vivo experiments containing only hydrogel that have cell infiltration effects are not considered relevant."}, {"lang": "zho", "source": "human translation", "topic_title": "\u6c34\u51dd\u80f6\u7ec6\u80de\u627f\u8f7d", "topic_description": "\u6211\u60f3\u8981\u770b\u5173\u4e8e\u6c34\u51dd\u80f6\u627f\u8f7d\u7ec6\u80de\u7684\u80fd\u529b\u7684\u76f8\u5173\u6587\u732e\u3002", "topic_narrative": ""}, {"lang": "zho", "source": "google translation", "topic_title": "\u6c34\u51dd\u80f6\u7ec6\u80de\u4fdd\u7559", "topic_description": "\u6211\u6b63\u5728\u5bfb\u627e\u4e0e\u6c34\u51dd\u80f6\u7ec6\u80de\u4fdd\u7559\u76f8\u5173\u7684\u6587\u7ae0\u3002", "topic_narrative": "\u6211\u6b63\u5728\u5bfb\u627e\u5173\u6ce8\u67d0\u4e9b\u7c7b\u578b\u7684\u6c34\u51dd\u80f6\u4e0e\u7ec6\u80de\u6df7\u5408\u65f6\u7684\u7ec6\u80de\u4fdd\u7559\u80fd\u529b\u7684\u6587\u7ae0\u3002\u76f8\u5173\u6587\u4ef6\u5fc5\u987b\u8ba8\u8bba\u6c34\u51dd\u80f6\u548c\u7ec6\u80de\u3002\u53ea\u8ba8\u8bba\u5176\u4e2d\u4e00\u4e2a\u800c\u4e0d\u8ba8\u8bba\u53e6\u4e00\u4e2a\u7684\u6587\u4ef6\u5c06\u88ab\u89c6\u4e3a\u4e0d\u76f8\u5173\u3002\u4ec5\u542b\u6709\u5177\u6709\u7ec6\u80de\u6d78\u6da6\u4f5c\u7528\u7684\u6c34\u51dd\u80f6\u7684\u4f53\u5185\u5b9e\u9a8c\u4e0d\u88ab\u8ba4\u4e3a\u662f\u76f8\u5173\u7684\u3002"}]}
{"topic_id": "22", "languages_with_qrels": [], "topics": [{"lang": "eng", "source": "original", "topic_title": "detector design of dark matter experiments", "topic_description": "I'm looking for information on the detector designs of dark matter experiments.", "topic_narrative": "Information on detector designs of experiments that aim to detect dark matter is relevant. If the document contains information on dark matter experiments, but is not focused on the detector design, it would be considered as somewhat valuable. If the document does not include a specific dark matter experiment, it would be considered not relevant."}, {"lang": "zho", "source": "human translation", "topic_title": "\u6697\u7269\u8d28\u5b9e\u9a8c\u7684\u63a2\u6d4b\u5668\u8bbe\u8ba1", "topic_description": "\u672c\u641c\u7d22\u65e8\u5728\u67e5\u627e\u6709\u5173\u6697\u7269\u8d28\u5b9e\u9a8c\u7684\u63a2\u6d4b\u5668\u8bbe\u8ba1\u7684\u4fe1\u606f\u3002", "topic_narrative": ""}, {"lang": "zho", "source": "google translation", "topic_title": "\u6697\u7269\u8d28\u5b9e\u9a8c\u63a2\u6d4b\u5668\u8bbe\u8ba1", "topic_description": "\u6211\u6b63\u5728\u5bfb\u627e\u6709\u5173\u6697\u7269\u8d28\u5b9e\u9a8c\u63a2\u6d4b\u5668\u8bbe\u8ba1\u7684\u4fe1\u606f\u3002", "topic_narrative": "\u6709\u5173\u65e8\u5728\u63a2\u6d4b\u6697\u7269\u8d28\u7684\u5b9e\u9a8c\u63a2\u6d4b\u5668\u8bbe\u8ba1\u7684\u4fe1\u606f\u662f\u76f8\u5173\u7684\u3002\u5982\u679c\u8be5\u6587\u4ef6\u5305\u542b\u6709\u5173\u6697\u7269\u8d28\u5b9e\u9a8c\u7684\u4fe1\u606f\uff0c\u4f46\u4e0d\u91cd\u70b9\u5173\u6ce8\u63a2\u6d4b\u5668\u8bbe\u8ba1\uff0c\u90a3\u4e48\u5b83\u5c06\u88ab\u8ba4\u4e3a\u5177\u6709\u4e00\u5b9a\u7684\u4ef7\u503c\u3002\u5982\u679c\u8be5\u6587\u4ef6\u4e0d\u5305\u542b\u7279\u5b9a\u7684\u6697\u7269\u8d28\u5b9e\u9a8c\uff0c\u5219\u5c06\u88ab\u89c6\u4e3a\u4e0d\u76f8\u5173\u3002"}]}
{"topic_id": "23", "languages_with_qrels": [], "topics": [{"lang": "eng", "source": "original", "topic_title": "in vivo or long-term stability of lipid nanoparticles", "topic_description": "I am looking for information about how to improve the in vivo or long-term stability of lipid nanoparticles (LNPs).", "topic_narrative": "Documents discussing different designs of lipid nanoparticles that affect their stability or related to examples of increasing LNP long-term stability, and principles on how LNP structures affect stability are considered relevant. Information that shows the importance of stability of drug carriers are also relevant. Information about general introduction of LNP, or LNP application in certain diseases are considered not relevant. Non-lipid-based nanoparticles are also not relevant."}, {"lang": "zho", "source": "human translation", "topic_title": "\u8102\u8d28\u7eb3\u7c73\u9897\u7c92\u7684\u4f53\u5185\u6216\u50a8\u5b58\u7a33\u5b9a\u6027", "topic_description": "\u6211\u60f3\u5bfb\u627e\u5173\u4e8e\u5982\u4f55\u63d0\u9ad8\u8102\u8d28\u7eb3\u7c73\u9897\u7c92\u7684\u4f53\u5185\u6216\u50a8\u5b58\u7a33\u5b9a\u6027\u7684\u6587\u7ae0\u3002", "topic_narrative": ""}, {"lang": "zho", "source": "google translation", "topic_title": "\u8102\u8d28\u7eb3\u7c73\u7c92\u5b50\u7684\u4f53\u5185\u6216\u957f\u671f\u7a33\u5b9a\u6027", "topic_description": "\u6211\u6b63\u5728\u5bfb\u627e\u6709\u5173\u5982\u4f55\u63d0\u9ad8\u8102\u8d28\u7eb3\u7c73\u9897\u7c92 (LNP) \u7684\u4f53\u5185\u6216\u957f\u671f\u7a33\u5b9a\u6027\u7684\u4fe1\u606f\u3002", "topic_narrative": "\u8ba8\u8bba\u5f71\u54cd\u200b\u200b\u5176\u7a33\u5b9a\u6027\u7684\u8102\u8d28\u7eb3\u7c73\u9897\u7c92\u7684\u4e0d\u540c\u8bbe\u8ba1\u6216\u4e0e\u589e\u52a0 LNP \u957f\u671f\u7a33\u5b9a\u6027\u7684\u793a\u4f8b\u76f8\u5173\u7684\u6587\u4ef6\uff0c\u4ee5\u53ca LNP \u7ed3\u6784\u5982\u4f55\u5f71\u54cd\u7a33\u5b9a\u6027\u7684\u539f\u7406\u88ab\u8ba4\u4e3a\u662f\u76f8\u5173\u7684\u3002\u663e\u793a\u836f\u7269\u8f7d\u4f53\u7a33\u5b9a\u6027\u91cd\u8981\u6027\u7684\u4fe1\u606f\u4e5f\u76f8\u5173\u3002\u6709\u5173 LNP \u7684\u4e00\u822c\u4ecb\u7ecd\u6216 LNP \u5728\u67d0\u4e9b\u75be\u75c5\u4e2d\u7684\u5e94\u7528\u7684\u4fe1\u606f\u88ab\u8ba4\u4e3a\u662f\u4e0d\u76f8\u5173\u7684\u3002\u975e\u8102\u8d28\u7eb3\u7c73\u9897\u7c92\u4e5f\u4e0d\u76f8\u5173\u3002"}]}
{"topic_id": "24", "languages_with_qrels": [], "topics": [{"lang": "eng", "source": "original", "topic_title": "commercial bank predicament in 2010s", "topic_description": "I want to find articles about the predicament of the commercial banks in the 2010s.", "topic_narrative": "Relevant articles should provide useful information about the situation of the commercial banks, not the central bank. Articles talking about some specific aspects of the predicament are also relevant. If the articles also bring up some solutions to the current situation, they can be very valuable. Articiles prior to 2010, even if they discuss problems with commercial banks are considered not relevant."}, {"lang": "zho", "source": "human translation", "topic_title": " \u56f0\u5883 \u5546\u4e1a\u7684 \u94f6\u884c 2010s", "topic_description": "\u6211\u60f3\u67e5\u627e\u6709\u51732010s\u5546\u4e1a\u94f6\u884c\u56f0\u5883\u7684\u6587\u732e\u8d44\u6599\u3002", "topic_narrative": ""}, {"lang": "zho", "source": "google translation", "topic_title": "2010\u5e74\u4ee3\u5546\u4e1a\u94f6\u884c\u7684\u56f0\u5883", "topic_description": "\u6211\u60f3\u627e\u4e00\u4e9b\u5173\u4e8e2010\u5e74\u4ee3\u5546\u4e1a\u94f6\u884c\u56f0\u5883\u7684\u6587\u7ae0\u3002", "topic_narrative": "\u76f8\u5173\u6587\u7ae0\u5e94\u8be5\u63d0\u4f9b\u6709\u5173\u5546\u4e1a\u94f6\u884c\u800c\u4e0d\u662f\u592e\u884c\u72b6\u51b5\u7684\u6709\u7528\u4fe1\u606f\u3002\u8ba8\u8bba\u56f0\u5883\u7684\u67d0\u4e9b\u5177\u4f53\u65b9\u9762\u7684\u6587\u7ae0\u4e5f\u5f88\u76f8\u5173\u3002\u5982\u679c\u8fd9\u4e9b\u6587\u7ae0\u8fd8\u9488\u5bf9\u5f53\u524d\u60c5\u51b5\u63d0\u51fa\u4e86\u4e00\u4e9b\u89e3\u51b3\u65b9\u6848\uff0c\u90a3\u4e48\u5b83\u4eec\u5c06\u975e\u5e38\u6709\u4ef7\u503c\u3002 2010\u5e74\u4e4b\u524d\u7684\u6587\u7ae0\uff0c\u5373\u4f7f\u8ba8\u8bba\u4e86\u5546\u4e1a\u94f6\u884c\u7684\u95ee\u9898\uff0c\u4e5f\u88ab\u8ba4\u4e3a\u662f\u4e0d\u76f8\u5173\u7684\u3002"}]}
{"topic_id": "25", "languages_with_qrels": [], "topics": [{"lang": "eng", "source": "original", "topic_title": "Self-assemble hydrogels in drug delivery", "topic_description": "I\u2018m looking for articles that describe applications of self-assemble hydrogels in drug delivery.", "topic_narrative": "Only articles that address clinical points, such as nanomolecules self-assembly, mechanical properties in drug delivery, drug release profiles, and different hydrogel matrices for anticancer drug loading and release will be considered relevant. If the articles focus on providing information on the latest techniques on advancing hydrogel-based biomaterial synthesis, such as 3D printing, it will not be considered relevant. Articles that only discuss the unique properties of hydrogels (biocompatibility, biodegradability and low cytotoxicity) which allow the possibility to tailor the hydrogel into an injectable gel should not be considered as relevant either."}, {"lang": "zho", "source": "human translation", "topic_title": "\u836f\u7269\u9012\u9001\u4e2d\u7684\u81ea\u7ec4\u88c5\u6c34\u51dd\u80f6", "topic_description": "\u6211\u9700\u8981\u67e5\u627e\u63cf\u8ff0\u81ea\u4e3b\u88c5\u6c34\u51dd\u80f6\u5e94\u7528\u4e8e\u836f\u7269\u9012\u9001\u7684\u6587\u732e\u3002", "topic_narrative": ""}, {"lang": "zho", "source": "google translation", "topic_title": "\u81ea\u7ec4\u88c5\u6c34\u51dd\u80f6\u5728\u836f\u7269\u8f93\u9001\u4e2d\u7684\u5e94\u7528", "topic_description": "\u6211\u6b63\u5728\u5bfb\u627e\u63cf\u8ff0\u81ea\u7ec4\u88c5\u6c34\u51dd\u80f6\u5728\u836f\u7269\u8f93\u9001\u4e2d\u5e94\u7528\u7684\u6587\u7ae0\u3002", "topic_narrative": "\u53ea\u6709\u6d89\u53ca\u4e34\u5e8a\u95ee\u9898\u7684\u6587\u7ae0\uff0c\u4f8b\u5982\u7eb3\u7c73\u5206\u5b50\u81ea\u7ec4\u88c5\u3001\u836f\u7269\u8f93\u9001\u7684\u673a\u68b0\u6027\u80fd\u3001\u836f\u7269\u91ca\u653e\u66f2\u7ebf\u4ee5\u53ca\u7528\u4e8e\u6297\u764c\u836f\u7269\u88c5\u8f7d\u548c\u91ca\u653e\u7684\u4e0d\u540c\u6c34\u51dd\u80f6\u57fa\u8d28\uff0c\u624d\u4f1a\u88ab\u8ba4\u4e3a\u662f\u76f8\u5173\u7684\u3002\u5982\u679c\u6587\u7ae0\u91cd\u70b9\u63d0\u4f9b\u6709\u5173\u63a8\u8fdb\u57fa\u4e8e\u6c34\u51dd\u80f6\u7684\u751f\u7269\u6750\u6599\u5408\u6210\u7684\u6700\u65b0\u6280\u672f\uff08\u4f8b\u5982 3D \u6253\u5370\uff09\u7684\u4fe1\u606f\uff0c\u5219\u4e0d\u4f1a\u88ab\u89c6\u4e3a\u76f8\u5173\u3002\u4ec5\u8ba8\u8bba\u6c34\u51dd\u80f6\u72ec\u7279\u6027\u8d28\uff08\u751f\u7269\u76f8\u5bb9\u6027\u3001\u751f\u7269\u964d\u89e3\u6027\u548c\u4f4e\u7ec6\u80de\u6bd2\u6027\uff09\u7684\u6587\u7ae0\u4e5f\u4e0d\u5e94\u88ab\u8ba4\u4e3a\u662f\u76f8\u5173\u7684\uff0c\u8fd9\u4e9b\u6027\u8d28\u5141\u8bb8\u5c06\u6c34\u51dd\u80f6\u5b9a\u5236\u6210\u53ef\u6ce8\u5c04\u51dd\u80f6\u3002"}]}
{"topic_id": "26", "languages_with_qrels": [], "topics": [{"lang": "eng", "source": "original", "topic_title": "drug conjugates glioblastoma", "topic_description": "I'm looking for articles that describe developments in drug conjugates for glioblastoma treatment.", "topic_narrative": "Only articles that provide information on the design of drug conjugates, mechanism of supramolecules passing through the Blood Brain Barrier (BBB), or drug conjugates release time in both in vivo and in vitro test would be considered relevant. If the article primarily discusses the formation of glioblastoma or physical treatments such as MRI and surgery, it is not considered relevant. Articles discussing other tumor types rather than glioblastoma would not be considered relevant either."}, {"lang": "zho", "source": "human translation", "topic_title": "\u8111\u80f6\u8d28\u7624\u5076\u8054\u836f\u7269", "topic_description": "\u6211\u60f3\u8981\u67e5\u627e\u63cf\u8ff0\u8111\u80f6\u8d28\u7624\u5076\u8054\u836f\u7269\u7684\u7814\u53d1\u8fdb\u5c55\u7684\u6587\u7ae0\u3002", "topic_narrative": ""}, {"lang": "zho", "source": "google translation", "topic_title": "\u80f6\u8d28\u6bcd\u7ec6\u80de\u7624\u836f\u7269\u7ed3\u5408\u7269", "topic_description": "\u6211\u6b63\u5728\u5bfb\u627e\u63cf\u8ff0\u80f6\u8d28\u6bcd\u7ec6\u80de\u7624\u6cbb\u7597\u836f\u7269\u5076\u8054\u7269\u8fdb\u5c55\u7684\u6587\u7ae0\u3002", "topic_narrative": "\u53ea\u6709\u63d0\u4f9b\u6709\u5173\u836f\u7269\u7f00\u5408\u7269\u8bbe\u8ba1\u3001\u8d85\u5206\u5b50\u7a7f\u8fc7\u8840\u8111\u5c4f\u969c (BBB) \u7684\u673a\u5236\u6216\u4f53\u5185\u548c\u4f53\u5916\u6d4b\u8bd5\u4e2d\u836f\u7269\u7f00\u5408\u7269\u91ca\u653e\u65f6\u95f4\u7684\u4fe1\u606f\u7684\u6587\u7ae0\u624d\u4f1a\u88ab\u89c6\u4e3a\u76f8\u5173\u3002\u5982\u679c\u6587\u7ae0\u4e3b\u8981\u8ba8\u8bba\u80f6\u8d28\u6bcd\u7ec6\u80de\u7624\u7684\u5f62\u6210\u6216\u7269\u7406\u6cbb\u7597\uff08\u4f8b\u5982 MRI \u548c\u624b\u672f\uff09\uff0c\u5219\u4e0d\u88ab\u8ba4\u4e3a\u662f\u76f8\u5173\u7684\u3002\u8ba8\u8bba\u9664\u80f6\u8d28\u6bcd\u7ec6\u80de\u7624\u4e4b\u5916\u7684\u5176\u4ed6\u80bf\u7624\u7c7b\u578b\u7684\u6587\u7ae0\u4e5f\u4e0d\u4f1a\u88ab\u8ba4\u4e3a\u662f\u76f8\u5173\u7684\u3002"}]}
{"topic_id": "27", "languages_with_qrels": [], "topics": [{"lang": "eng", "source": "original", "topic_title": "non-viral drug delivery for neurodegenerative disease", "topic_description": "I am looking for information that introduces how non-viral drug delivery vectors might be used in the treatment of neurodegenerative diseases, such as Parkinson's, Alzheimer's diseases, and their advantages over traditional drug delivery methods.", "topic_narrative": "Documents that introduce research results of non-viral drug delivery vectors in the treatment of neurodegenerative diseases and provide research result related to non-viral vectors in brain delivery or neurodegenerative diseases are relevant. Introduction of recent drug development or potential target sites are somewhat valuable. Results that introduce non-viral vectors in other fields of application, or focus on viral vectors, or treatment of neurodegenerative diseases are irrelevant. Results that focus on specific neurodegenerative diseases and their pathological reasoning or treatment are also irrelevant."}, {"lang": "zho", "source": "human translation", "topic_title": "\u6cbb\u7597\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u7684\u975e\u75c5\u6bd2\u836f\u7269\u9012\u9001\u8f7d\u4f53", "topic_description": "\u6211\u60f3\u5bfb\u627e\u5173\u4e8e\u975e\u75c5\u6bd2\u836f\u7269\u9012\u9001\u5728\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\uff08\u4f8b\u5982\u5e15\u91d1\u68ee\u75c5\uff0c\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\uff09\u6cbb\u7597\u4e0a\u6f5c\u5728\u5e94\u7528\u7684\u6587\u7ae0\u548c\u4fe1\u606f\uff0c\u4ee5\u53ca\u5b83\u4eec\u5bf9\u4f20\u7edf\u836f\u7269\u9012\u9001\u65b9\u6cd5\u7684\u4f18\u52bf\u3002", "topic_narrative": ""}, {"lang": "zho", "source": "google translation", "topic_title": "\u6cbb\u7597\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u7684\u975e\u75c5\u6bd2\u836f\u7269\u9012\u9001", "topic_description": "\u6211\u6b63\u5728\u5bfb\u627e\u4ecb\u7ecd\u975e\u75c5\u6bd2\u836f\u7269\u9012\u9001\u8f7d\u4f53\u5982\u4f55\u7528\u4e8e\u6cbb\u7597\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\uff08\u4f8b\u5982\u5e15\u91d1\u68ee\u75c5\u3001\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\uff09\u53ca\u5176\u76f8\u5bf9\u4e8e\u4f20\u7edf\u836f\u7269\u9012\u9001\u65b9\u6cd5\u7684\u4f18\u52bf\u7684\u4fe1\u606f\u3002", "topic_narrative": "\u4ecb\u7ecd\u975e\u75c5\u6bd2\u836f\u7269\u9012\u9001\u8f7d\u4f53\u5728\u6cbb\u7597\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u4e2d\u7684\u7814\u7a76\u6210\u679c\u5e76\u63d0\u4f9b\u4e0e\u975e\u75c5\u6bd2\u8f7d\u4f53\u5728\u8111\u9012\u9001\u6216\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u4e2d\u76f8\u5173\u7684\u7814\u7a76\u7ed3\u679c\u7684\u6587\u732e\u662f\u76f8\u5173\u7684\u3002\u4ecb\u7ecd\u6700\u8fd1\u7684\u836f\u7269\u5f00\u53d1\u6216\u6f5c\u5728\u7684\u9776\u70b9\u662f\u6709\u4e00\u5b9a\u4ef7\u503c\u7684\u3002\u5728\u5176\u4ed6\u5e94\u7528\u9886\u57df\u5f15\u5165\u975e\u75c5\u6bd2\u8f7d\u4f53\u3001\u6216\u5173\u6ce8\u75c5\u6bd2\u8f7d\u4f53\u3001\u6216\u6cbb\u7597\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u7684\u7ed3\u679c\u90fd\u662f\u65e0\u5173\u7d27\u8981\u7684\u3002\u4e13\u6ce8\u4e8e\u7279\u5b9a\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u53ca\u5176\u75c5\u7406\u63a8\u7406\u6216\u6cbb\u7597\u7684\u7ed3\u679c\u4e5f\u662f\u65e0\u5173\u7d27\u8981\u7684\u3002"}]}
{"topic_id": "28", "languages_with_qrels": [], "topics": [{"lang": "eng", "source": "original", "topic_title": "Interleukin's function in tumor suppression", "topic_description": "I am looking for articles discussing the function of interleukins involved in suppressing tumor growth.", "topic_narrative": "Only articles focusing on interleukins' function in tumor suppression are considered relevant. Articles discussing other functions of the interleukin except for tumor suppression are not considered relevant. Also, articles about the secretion or metastasis of the interleukins are not considered as relevant."}, {"lang": "zho", "source": "human translation", "topic_title": "\u767d\u7ec6\u80de\u4ecb\u7d20\u7684\u80bf\u7624\u6291\u5236\u529f\u80fd", "topic_description": "\u6211\u60f3\u8981\u770b\u4e0e\u767d\u7ec6\u80de\u4ecb\u7d20\u6291\u5236\u80bf\u7624\u76f8\u5173\u7684\u673a\u5236\u7684\u6587\u7ae0\u3002", "topic_narrative": ""}, {"lang": "zho", "source": "google translation", "topic_title": "\u767d\u4ecb\u7d20\u5728\u80bf\u7624\u6291\u5236\u4e2d\u7684\u4f5c\u7528", "topic_description": "\u6211\u6b63\u5728\u5bfb\u627e\u8ba8\u8bba\u767d\u7ec6\u80de\u4ecb\u7d20\u6291\u5236\u80bf\u7624\u751f\u957f\u7684\u529f\u80fd\u7684\u6587\u7ae0\u3002", "topic_narrative": "\u53ea\u6709\u5173\u6ce8\u767d\u7ec6\u80de\u4ecb\u7d20\u5728\u80bf\u7624\u6291\u5236\u4e2d\u7684\u529f\u80fd\u7684\u6587\u7ae0\u624d\u88ab\u8ba4\u4e3a\u662f\u76f8\u5173\u7684\u3002\u8ba8\u8bba\u767d\u7ec6\u80de\u4ecb\u7d20\u9664\u80bf\u7624\u6291\u5236\u4e4b\u5916\u7684\u5176\u4ed6\u529f\u80fd\u7684\u6587\u7ae0\u4e0d\u88ab\u8ba4\u4e3a\u662f\u76f8\u5173\u7684\u3002\u6b64\u5916\uff0c\u6709\u5173\u767d\u7ec6\u80de\u4ecb\u7d20\u5206\u6ccc\u6216\u8f6c\u79fb\u7684\u6587\u7ae0\u4e0d\u88ab\u8ba4\u4e3a\u662f\u76f8\u5173\u7684\u3002"}]}
{"topic_id": "29", "languages_with_qrels": [], "topics": [{"lang": "eng", "source": "original", "topic_title": "Immunogenic cell death", "topic_description": "I'm looking for articles discussing mechanisms of immunogenic cell death (ICD).", "topic_narrative": "Only articles discussing principles and mechanisms of immunogenic cell death (ICD) and providing information of damage-associated molecular patterns (DAMPs that include ER stress, ATP secretion during apoptosis and HMGB1 release) would be considered relevant. If the article primarily discusses the tumor microenvironment and other immunogenic response, it is not considered relevant. Articles only sharing information of anticancer treatments that can induce ICD will not be considered relevant either."}, {"lang": "zho", "source": "human translation", "topic_title": "\u514d\u75ab\u539f\u6027\u7ec6\u80de\u51cb\u4ea1", "topic_description": "\u6211\u8981\u67e5\u627e\u8ba8\u8bba\u514d\u75ab\u539f\u6027\u7ec6\u80de\u51cb\u4ea1\uff08ICD\uff09\u673a\u5236\u7684\u6587\u7ae0\u3002", "topic_narrative": ""}, {"lang": "zho", "source": "google translation", "topic_title": "\u514d\u75ab\u539f\u6027\u7ec6\u80de\u6b7b\u4ea1", "topic_description": "\u6211\u6b63\u5728\u5bfb\u627e\u8ba8\u8bba\u514d\u75ab\u539f\u6027\u7ec6\u80de\u6b7b\u4ea1 (ICD) \u673a\u5236\u7684\u6587\u7ae0\u3002", "topic_narrative": "\u53ea\u6709\u8ba8\u8bba\u514d\u75ab\u539f\u6027\u7ec6\u80de\u6b7b\u4ea1 (ICD) \u539f\u7406\u548c\u673a\u5236\u5e76\u63d0\u4f9b\u635f\u4f24\u76f8\u5173\u5206\u5b50\u6a21\u5f0f\u4fe1\u606f\uff08DAMP\uff0c\u5305\u62ec ER \u5e94\u6fc0\u3001\u7ec6\u80de\u51cb\u4ea1\u8fc7\u7a0b\u4e2d ATP \u5206\u6ccc\u548c HMGB1 \u91ca\u653e\uff09\u7684\u6587\u7ae0\u624d\u4f1a\u88ab\u89c6\u4e3a\u76f8\u5173\u3002\u5982\u679c\u6587\u7ae0\u4e3b\u8981\u8ba8\u8bba\u80bf\u7624\u5fae\u73af\u5883\u548c\u5176\u4ed6\u514d\u75ab\u539f\u6027\u53cd\u5e94\uff0c\u5219\u4e0d\u88ab\u8ba4\u4e3a\u662f\u76f8\u5173\u7684\u3002\u4ec5\u5206\u4eab\u53ef\u8bf1\u53d1 ICD \u7684\u6297\u764c\u6cbb\u7597\u4fe1\u606f\u7684\u6587\u7ae0\u4e5f\u4e0d\u4f1a\u88ab\u89c6\u4e3a\u76f8\u5173\u3002"}]}
{"topic_id": "30", "languages_with_qrels": [], "topics": [{"lang": "eng", "source": "original", "topic_title": "white beige adipocyte conversion", "topic_description": "I am looking for articles discussing the conversion between white adipocyte and beige adipocytes.", "topic_narrative": "Only articles that contain information about the conversation between a white adipocyte cell type and a beige adipocyte cell type are considered relevant. Articles discussing brown adipocytes instead of beige adipocytes are not considered relevant. An article that discusses one cell type but only mentions another cell type without the process of the conversion is not considered relevant."}, {"lang": "zho", "source": "human translation", "topic_title": "\u767d\u8272\u4e0e\u7c73\u8272\u8102\u80aa\u8f6c\u5316", "topic_description": "\u6211\u60f3\u8981\u770b\u767d\u8272\u4e0e\u7c73\u8272\u8102\u80aa\u76f8\u5173\u7684\u6587\u7ae0\u3002", "topic_narrative": ""}, {"lang": "zho", "source": "google translation", "topic_title": "\u767d\u8272\u7c73\u8272\u8102\u80aa\u7ec6\u80de\u8f6c\u5316", "topic_description": "\u6211\u6b63\u5728\u5bfb\u627e\u8ba8\u8bba\u767d\u8272\u8102\u80aa\u7ec6\u80de\u548c\u7c73\u8272\u8102\u80aa\u7ec6\u80de\u4e4b\u95f4\u8f6c\u6362\u7684\u6587\u7ae0\u3002", "topic_narrative": "\u53ea\u6709\u5305\u542b\u6709\u5173\u767d\u8272\u8102\u80aa\u7ec6\u80de\u7c7b\u578b\u548c\u7c73\u8272\u8102\u80aa\u7ec6\u80de\u7c7b\u578b\u4e4b\u95f4\u5bf9\u8bdd\u4fe1\u606f\u7684\u6587\u7ae0\u624d\u88ab\u89c6\u4e3a\u76f8\u5173\u3002\u8ba8\u8bba\u68d5\u8272\u8102\u80aa\u7ec6\u80de\u800c\u4e0d\u662f\u7c73\u8272\u8102\u80aa\u7ec6\u80de\u7684\u6587\u7ae0\u88ab\u8ba4\u4e3a\u4e0d\u76f8\u5173\u3002\u8ba8\u8bba\u4e00\u79cd\u7ec6\u80de\u7c7b\u578b\u4f46\u4ec5\u63d0\u53ca\u53e6\u4e00\u79cd\u7ec6\u80de\u7c7b\u578b\u800c\u6ca1\u6709\u8f6c\u6362\u8fc7\u7a0b\u7684\u6587\u7ae0\u88ab\u8ba4\u4e3a\u662f\u4e0d\u76f8\u5173\u7684\u3002"}]}
{"topic_id": "31", "languages_with_qrels": [], "topics": [{"lang": "eng", "source": "original", "topic_title": "scintillating crystal detectors in particle experiments", "topic_description": "I'm looking for information on scintillating crystal detectors in particle experiments.", "topic_narrative": "Information on scintillating crystal detectors used in particle experiments is relevant. If the article includes scintillating crystal detectors, but does not include their use in particle experiments, it would be considered as not valuable. Also, if the article does not include scintillating crystal detectors at all, it would be considered as not relevant."}, {"lang": "zho", "source": "human translation", "topic_title": "\u7c92\u5b50\u7269\u7406\u5b9e\u9a8c\u4e2d\u7684\u95ea\u70c1\u6676\u4f53\u63a2\u6d4b\u5668", "topic_description": "\u672c\u641c\u7d22\u65e8\u5728\u67e5\u627e\u6709\u5173\u7c92\u5b50\u7269\u7406\u5b9e\u9a8c\u4e2d\u5e94\u7528\u7684\u95ea\u70c1\u6676\u4f53\u63a2\u6d4b\u5668\u7684\u5185\u5bb9\u3002", "topic_narrative": ""}, {"lang": "zho", "source": "google translation", "topic_title": "\u7c92\u5b50\u5b9e\u9a8c\u4e2d\u7684\u95ea\u70c1\u6676\u4f53\u63a2\u6d4b\u5668", "topic_description": "\u6211\u6b63\u5728\u5bfb\u627e\u6709\u5173\u7c92\u5b50\u5b9e\u9a8c\u4e2d\u95ea\u70c1\u6676\u4f53\u63a2\u6d4b\u5668\u7684\u4fe1\u606f\u3002", "topic_narrative": "\u6709\u5173\u7c92\u5b50\u5b9e\u9a8c\u4e2d\u4f7f\u7528\u7684\u95ea\u70c1\u6676\u4f53\u63a2\u6d4b\u5668\u7684\u4fe1\u606f\u662f\u76f8\u5173\u7684\u3002\u5982\u679c\u6587\u7ae0\u5305\u542b\u95ea\u70c1\u6676\u4f53\u63a2\u6d4b\u5668\uff0c\u4f46\u4e0d\u5305\u542b\u5b83\u4eec\u5728\u7c92\u5b50\u5b9e\u9a8c\u4e2d\u7684\u5e94\u7528\uff0c\u90a3\u4e48\u5b83\u5c06\u88ab\u8ba4\u4e3a\u6ca1\u6709\u4ef7\u503c\u3002\u6b64\u5916\uff0c\u5982\u679c\u8be5\u6587\u7ae0\u6839\u672c\u4e0d\u5305\u62ec\u95ea\u70c1\u6676\u4f53\u63a2\u6d4b\u5668\uff0c\u5b83\u5c06\u88ab\u89c6\u4e3a\u4e0d\u76f8\u5173\u3002"}]}
{"topic_id": "32", "languages_with_qrels": [], "topics": [{"lang": "eng", "source": "original", "topic_title": "redox reaction electron transfer", "topic_description": "How to define a redox reaction?", "topic_narrative": "A relevant document will describe the redox reaction and must describe the electron transfer within the oxidant and reductant. A very valuable article will mention that chemical valence is changing during the reaction. A document is not relevant if it does not describe the entire redox reaction or gives an example of a redox reaction without describing the process."}, {"lang": "zho", "source": "human translation", "topic_title": "\u6c27\u5316\u8fd8\u539f\u53cd\u5e94 \u7535\u5b50\u8f6c\u79fb", "topic_description": "\u5982\u4f55\u53bb\u5b9a\u4e49\u4e00\u4e2a\u6c27\u5316\u8fd8\u539f\u53cd\u5e94\uff1f", "topic_narrative": ""}, {"lang": "zho", "source": "google translation", "topic_title": "\u6c27\u5316\u8fd8\u539f\u53cd\u5e94\u7535\u5b50\u8f6c\u79fb", "topic_description": "\u5982\u4f55\u5b9a\u4e49\u6c27\u5316\u8fd8\u539f\u53cd\u5e94\uff1f", "topic_narrative": "\u76f8\u5173\u6587\u4ef6\u5c06\u63cf\u8ff0\u6c27\u5316\u8fd8\u539f\u53cd\u5e94\uff0c\u5e76\u4e14\u5fc5\u987b\u63cf\u8ff0\u6c27\u5316\u5242\u548c\u8fd8\u539f\u5242\u5185\u7684\u7535\u5b50\u8f6c\u79fb\u3002\u4e00\u7bc7\u975e\u5e38\u6709\u4ef7\u503c\u7684\u6587\u7ae0\u4f1a\u63d0\u5230\u5316\u5b66\u4ef7\u5728\u53cd\u5e94\u8fc7\u7a0b\u4e2d\u53d1\u751f\u53d8\u5316\u3002\u5982\u679c\u6587\u4ef6\u6ca1\u6709\u63cf\u8ff0\u6574\u4e2a\u6c27\u5316\u8fd8\u539f\u53cd\u5e94\u6216\u7ed9\u51fa\u4e86\u6c27\u5316\u8fd8\u539f\u53cd\u5e94\u7684\u793a\u4f8b\u4f46\u6ca1\u6709\u63cf\u8ff0\u8fc7\u7a0b\uff0c\u5219\u8be5\u6587\u4ef6\u662f\u4e0d\u76f8\u5173\u7684\u3002"}]}
{"topic_id": "33", "languages_with_qrels": [], "topics": [{"lang": "eng", "source": "original", "topic_title": "macroeconomic influence corporate capital structure", "topic_description": "I am looking for information about the influence of macroeconomic factors on corporate capital structure.", "topic_narrative": "Relevant articles should talk about macroeconomic factors, but not any other economic factors. Articles analyzing the influence on a specific company are considered relevant. Articles talking about several influencing factors, which include the macroeconomic factors, of the corporate capital structures are deemed somewhat valuable."}, {"lang": "zho", "source": "human translation", "topic_title": "\u5b8f\u89c2\u7ecf\u6d4e \u5f71\u54cd \u516c\u53f8 \u8d44\u672c \u7ed3\u6784", "topic_description": "\u6211\u5728\u5bfb\u627e\u5b8f\u89c2\u7ecf\u6d4e\u56e0\u7d20\u5bf9\u516c\u53f8\u8d44\u672c\u7ed3\u6784\u5f71\u54cd\u7684\u6709\u5173\u7814\u7a76\u3002", "topic_narrative": ""}, {"lang": "zho", "source": "google translation", "topic_title": "\u5b8f\u89c2\u7ecf\u6d4e\u5f71\u54cd\u4f01\u4e1a\u8d44\u672c\u7ed3\u6784", "topic_description": "\u6211\u6b63\u5728\u5bfb\u627e\u6709\u5173\u5b8f\u89c2\u7ecf\u6d4e\u56e0\u7d20\u5bf9\u4f01\u4e1a\u8d44\u672c\u7ed3\u6784\u5f71\u54cd\u7684\u4fe1\u606f\u3002", "topic_narrative": "\u76f8\u5173\u6587\u7ae0\u5e94\u8be5\u8c08\u8bba\u5b8f\u89c2\u7ecf\u6d4e\u56e0\u7d20\uff0c\u800c\u4e0d\u662f\u4efb\u4f55\u5176\u4ed6\u7ecf\u6d4e\u56e0\u7d20\u3002\u5206\u6790\u5bf9\u7279\u5b9a\u516c\u53f8\u5f71\u54cd\u7684\u6587\u7ae0\u88ab\u8ba4\u4e3a\u662f\u76f8\u5173\u7684\u3002\u8ba8\u8bba\u516c\u53f8\u8d44\u672c\u7ed3\u6784\u7684\u51e0\u4e2a\u5f71\u54cd\u56e0\u7d20\uff08\u5305\u62ec\u5b8f\u89c2\u7ecf\u6d4e\u56e0\u7d20\uff09\u7684\u6587\u7ae0\u88ab\u8ba4\u4e3a\u662f\u6709\u4ef7\u503c\u7684\u3002"}]}
{"topic_id": "34", "languages_with_qrels": [], "topics": [{"lang": "eng", "source": "original", "topic_title": "liquid scintillator in neutrino experiment", "topic_description": "I'm looking for information on studies of liquid scintillators for neutrino experiments.", "topic_narrative": "Information on technical details of liquid scintillators proposed for use in neutrino experiments are considered relevant. If the article only mentions general information about the technical design of the neutrino experiment, but does not mention the liquid scintillator, then it would be considered as somewhat valuable. Also, if it mentions liquid scintillators but not used for neutrino experiments, it would also be considered as somewhat valuable. If the article does not mention either neutrino experiments or liquid scintillators, it would be considered as not relevant."}, {"lang": "zho", "source": "human translation", "topic_title": "\u4e2d\u5fae\u5b50\u5b9e\u9a8c\u4e2d\u7684\u6db2\u4f53\u95ea\u70c1\u63a2\u6d4b\u5668", "topic_description": "\u672c\u641c\u7d22\u65e8\u5728\u67e5\u627e\u6709\u5173\u5e94\u7528\u5728\u4e2d\u5fae\u5b50\u5b9e\u9a8c\u4e2d\u7684\u6db2\u4f53\u95ea\u70c1\u63a2\u6d4b\u5668\u7684\u7814\u7a76\u3002", "topic_narrative": ""}, {"lang": "zho", "source": "google translation", "topic_title": "\u4e2d\u5fae\u5b50\u5b9e\u9a8c\u4e2d\u7684\u6db2\u4f53\u95ea\u70c1\u4f53", "topic_description": "\u6211\u6b63\u5728\u5bfb\u627e\u6709\u5173\u4e2d\u5fae\u5b50\u5b9e\u9a8c\u6db2\u4f53\u95ea\u70c1\u4f53\u7814\u7a76\u7684\u4fe1\u606f\u3002", "topic_narrative": "\u6709\u5173\u5efa\u8bae\u7528\u4e8e\u4e2d\u5fae\u5b50\u5b9e\u9a8c\u7684\u6db2\u4f53\u95ea\u70c1\u4f53\u6280\u672f\u7ec6\u8282\u7684\u4fe1\u606f\u88ab\u8ba4\u4e3a\u662f\u76f8\u5173\u7684\u3002\u5982\u679c\u6587\u7ae0\u53ea\u63d0\u5230\u4e2d\u5fae\u5b50\u5b9e\u9a8c\u6280\u672f\u8bbe\u8ba1\u7684\u4e00\u822c\u4fe1\u606f\uff0c\u800c\u6ca1\u6709\u63d0\u5230\u6db2\u4f53\u95ea\u70c1\u4f53\uff0c\u90a3\u4e48\u5b83\u4f1a\u88ab\u8ba4\u4e3a\u662f\u6709\u4e00\u5b9a\u4ef7\u503c\u7684\u3002\u53e6\u5916\uff0c\u5982\u679c\u5b83\u63d0\u5230\u6db2\u4f53\u95ea\u70c1\u4f53\u4f46\u4e0d\u7528\u4e8e\u4e2d\u5fae\u5b50\u5b9e\u9a8c\uff0c\u5b83\u4e5f\u4f1a\u88ab\u8ba4\u4e3a\u662f\u6709\u4e00\u5b9a\u4ef7\u503c\u7684\u3002\u5982\u679c\u6587\u7ae0\u6ca1\u6709\u63d0\u53ca\u4e2d\u5fae\u5b50\u5b9e\u9a8c\u6216\u6db2\u4f53\u95ea\u70c1\u4f53\uff0c\u5219\u5c06\u88ab\u89c6\u4e3a\u4e0d\u76f8\u5173\u3002"}]}
{"topic_id": "35", "languages_with_qrels": [], "topics": [{"lang": "eng", "source": "original", "topic_title": "receptor neuron regeneration", "topic_description": "I am looking for articles discussing neuron cell regeneration receptors.", "topic_narrative": "Only articles discussing cell receptors that have effect on neuron regeneration are considered relevant. Articles related to cell receptors but are not connected to neuron regeneration are not considered relevant. In addition, other discussions focusing on neuron regeneration but are not from cellular receptors are also not considered relevant."}, {"lang": "zho", "source": "human translation", "topic_title": "\u795e\u7ecf\u4fee\u590d\u76f8\u5173\u7ec6\u80de\u53d7\u4f53", "topic_description": "\u6211\u60f3\u8981\u770b\u8ba8\u8bba\u5bf9\u795e\u7ecf\u4fee\u590d\u6709\u5f71\u54cd\u7684\u7ec6\u80de\u53d7\u4f53\u7684\u6587\u7ae0\u3002", "topic_narrative": ""}, {"lang": "zho", "source": "google translation", "topic_title": "\u53d7\u4f53\u795e\u7ecf\u5143\u518d\u751f", "topic_description": "\u6211\u6b63\u5728\u5bfb\u627e\u8ba8\u8bba\u795e\u7ecf\u5143\u7ec6\u80de\u518d\u751f\u53d7\u4f53\u7684\u6587\u7ae0\u3002", "topic_narrative": "\u53ea\u6709\u8ba8\u8bba\u5bf9\u795e\u7ecf\u5143\u518d\u751f\u6709\u5f71\u54cd\u7684\u7ec6\u80de\u53d7\u4f53\u7684\u6587\u7ae0\u624d\u88ab\u8ba4\u4e3a\u662f\u76f8\u5173\u7684\u3002\u4e0e\u7ec6\u80de\u53d7\u4f53\u76f8\u5173\u4f46\u4e0e\u795e\u7ecf\u5143\u518d\u751f\u65e0\u5173\u7684\u6587\u7ae0\u4e0d\u88ab\u8ba4\u4e3a\u662f\u76f8\u5173\u7684\u3002\u6b64\u5916\uff0c\u5176\u4ed6\u5173\u6ce8\u795e\u7ecf\u5143\u518d\u751f\u4f46\u4e0d\u662f\u6765\u81ea\u7ec6\u80de\u53d7\u4f53\u7684\u8ba8\u8bba\u4e5f\u88ab\u8ba4\u4e3a\u4e0d\u76f8\u5173\u3002"}]}
{"topic_id": "36", "languages_with_qrels": [], "topics": [{"lang": "eng", "source": "original", "topic_title": "LNPs, blood-brain barrier, mRNA delivery", "topic_description": "I looking for documents about Lipid nanoparticle (LNP) carriers for mRNA delivery in blood-brain barrier (BBB).", "topic_narrative": "Lipid nanoparticles (LNPs) act as a common drug delivery carrier, suitable for carrying mRNA to a target site. Relevant documents will discuss designs of mRNA carrying LNPs used in the blood-brain barrier (BBB) delivery, which include their formulation, characterization, and performance. Documents discussing the progress of research on mRNA delivery or LNP delivery across the BBB are also considered relevant. Information about the other delivery vectors and other cargos are not considered relevant."}, {"lang": "zho", "source": "human translation", "topic_title": "\u8102\u8d28\u7eb3\u7c73\u9897\u7c92\u5bf9\u8840\u8111\u5c4f\u969c\u7684mRNA\u9012\u9001", "topic_description": "\u6211\u5728\u5bfb\u627e\u5173\u4e8e\u643a\u5e26mRNA\u5206\u5b50\u7684\u8102\u8d28\u7eb3\u7c73\u9897\u7c92\u7a7f\u900f\u8840\u8111\u5c4f\u969c\u7684\u8d44\u6599\u3002", "topic_narrative": ""}, {"lang": "zho", "source": "google translation", "topic_title": "LNP\u3001\u8840\u8111\u5c4f\u969c\u3001mRNA \u9012\u9001", "topic_description": "\u6211\u6b63\u5728\u5bfb\u627e\u6709\u5173\u7528\u4e8e\u8840\u8111\u5c4f\u969c (BBB) \u4e2d mRNA \u4f20\u9012\u7684\u8102\u8d28\u7eb3\u7c73\u9897\u7c92 (LNP) \u8f7d\u4f53\u7684\u6587\u6863\u3002", "topic_narrative": "\u8102\u8d28\u7eb3\u7c73\u9897\u7c92 (LNP) \u4f5c\u4e3a\u5e38\u89c1\u7684\u836f\u7269\u9012\u9001\u8f7d\u4f53\uff0c\u9002\u5408\u5c06 mRNA \u8fd0\u8f7d\u81f3\u9776\u4f4d\u70b9\u3002\u76f8\u5173\u6587\u4ef6\u5c06\u8ba8\u8bba\u7528\u4e8e\u8840\u8111\u5c4f\u969c (BBB) \u9012\u9001\u7684\u643a\u5e26 LNP \u7684 mRNA \u7684\u8bbe\u8ba1\uff0c\u5305\u62ec\u5176\u914d\u65b9\u3001\u8868\u5f81\u548c\u6027\u80fd\u3002\u8ba8\u8bba mRNA \u9012\u9001\u6216 LNP \u8de8 BBB \u9012\u9001\u7684\u7814\u7a76\u8fdb\u5c55\u7684\u6587\u4ef6\u4e5f\u88ab\u8ba4\u4e3a\u662f\u76f8\u5173\u7684\u3002\u6709\u5173\u5176\u4ed6\u8fd0\u8f93\u5a92\u4ecb\u548c\u5176\u4ed6\u8d27\u7269\u7684\u4fe1\u606f\u4e0d\u88ab\u8ba4\u4e3a\u662f\u76f8\u5173\u7684\u3002"}]}
{"topic_id": "37", "languages_with_qrels": [], "topics": [{"lang": "eng", "source": "original", "topic_title": "Microglia-targeting nanotherapeutics", "topic_description": "I'm looking for articles discussing the microglia-targeting nanotherapeutics for neurodegenerative diseases.", "topic_narrative": "Only articles discussing microglia-nanotherapeutic platforms that could address the challenges of targeted delivery of active therapeutic agents to the central nervous system (CNS) will be considered relevant. Articles primarily discuss the functions of microglia and the mechanisms of their modulation to CNS will not consider as relevant. Articles only discussing neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease, will not be considered relevant either."}, {"lang": "zho", "source": "human translation", "topic_title": "\u5c0f\u80f6\u8d28\u7ec6\u80de\u9776\u5411\u7eb3\u7c73\u7597\u6cd5", "topic_description": " \u6211\u9700\u8981\u67e5\u627e\u5173\u4e8e\u795e\u7ecf\u9000\u5316\u6027\u75be\u75c5\u7684\u5c0f\u80f6\u8d28\u7ec6\u80de\u9776\u5411\u7eb3\u7c73\u7597\u6cd5\u7684\u6587\u732e\u3002", "topic_narrative": ""}, {"lang": "zho", "source": "google translation", "topic_title": "\u9776\u5411\u5c0f\u80f6\u8d28\u7ec6\u80de\u7684\u7eb3\u7c73\u7597\u6cd5", "topic_description": "\u6211\u6b63\u5728\u5bfb\u627e\u8ba8\u8bba\u9488\u5bf9\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u7684\u5c0f\u80f6\u8d28\u7ec6\u80de\u9776\u5411\u7eb3\u7c73\u7597\u6cd5\u7684\u6587\u7ae0\u3002", "topic_narrative": "\u53ea\u6709\u8ba8\u8bba\u5c0f\u80f6\u8d28\u7ec6\u80de\u7eb3\u7c73\u6cbb\u7597\u5e73\u53f0\u3001\u80fd\u591f\u89e3\u51b3\u5411\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf (CNS) \u9776\u5411\u9012\u9001\u6d3b\u6027\u6cbb\u7597\u5242\u7684\u6311\u6218\u7684\u6587\u7ae0\u624d\u4f1a\u88ab\u8ba4\u4e3a\u662f\u76f8\u5173\u7684\u3002\u4e3b\u8981\u8ba8\u8bba\u5c0f\u80f6\u8d28\u7ec6\u80de\u7684\u529f\u80fd\u53ca\u5176\u5bf9\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u7684\u8c03\u8282\u673a\u5236\u7684\u6587\u7ae0\u5c06\u4e0d\u88ab\u8ba4\u4e3a\u662f\u76f8\u5173\u7684\u3002\u4ec5\u8ba8\u8bba\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u548c\u5e15\u91d1\u68ee\u75c5\u7b49\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u7684\u6587\u7ae0\u4e5f\u4e0d\u4f1a\u88ab\u89c6\u4e3a\u76f8\u5173\u3002"}]}
{"topic_id": "38", "languages_with_qrels": [], "topics": [{"lang": "eng", "source": "original", "topic_title": "detector designs of a heavy ion collider", "topic_description": "I'm looking for information on detector designs of a heavy ion collider.", "topic_narrative": "Information on the designs of a heavy ion collider is relevant. If the article only contains general information on the heavy ion collider or heavy ion detectors but does not discuss its design, it would be considered as somewhat valuable. If it does not mention the heavy ion collider at all, it would be considered not valuable."}, {"lang": "zho", "source": "human translation", "topic_title": "\u91cd\u79bb\u5b50\u52a0\u901f\u5668\u7684\u63a2\u6d4b\u5668\u8bbe\u8ba1", "topic_description": "\u672c\u641c\u7d22\u65e8\u5728\u67e5\u627e\u6709\u5173\u91cd\u79bb\u5b50\u52a0\u901f\u5668\u63a2\u6d4b\u5668\u8bbe\u8ba1\u7684\u5185\u5bb9\u3002", "topic_narrative": ""}, {"lang": "zho", "source": "google translation", "topic_title": "\u91cd\u79bb\u5b50\u5bf9\u649e\u673a\u63a2\u6d4b\u5668\u8bbe\u8ba1", "topic_description": "\u6211\u6b63\u5728\u5bfb\u627e\u6709\u5173\u91cd\u79bb\u5b50\u5bf9\u649e\u673a\u63a2\u6d4b\u5668\u8bbe\u8ba1\u7684\u4fe1\u606f\u3002", "topic_narrative": "\u6709\u5173\u91cd\u79bb\u5b50\u5bf9\u649e\u673a\u8bbe\u8ba1\u7684\u4fe1\u606f\u662f\u76f8\u5173\u7684\u3002\u5982\u679c\u8fd9\u7bc7\u6587\u7ae0\u53ea\u5305\u542b\u91cd\u79bb\u5b50\u5bf9\u649e\u673a\u6216\u91cd\u79bb\u5b50\u63a2\u6d4b\u5668\u7684\u4e00\u822c\u4fe1\u606f\uff0c\u4f46\u4e0d\u8ba8\u8bba\u5176\u8bbe\u8ba1\uff0c\u90a3\u4e48\u5b83\u4f1a\u88ab\u8ba4\u4e3a\u662f\u6709\u4e00\u5b9a\u4ef7\u503c\u7684\u3002\u5982\u679c\u6839\u672c\u4e0d\u63d0\u91cd\u79bb\u5b50\u5bf9\u649e\u673a\uff0c\u90a3\u5c31\u88ab\u8ba4\u4e3a\u6ca1\u6709\u4ef7\u503c\u3002"}]}
{"topic_id": "39", "languages_with_qrels": [], "topics": [{"lang": "eng", "source": "original", "topic_title": "polymer nanoparticle size control", "topic_description": "I am looking for articles discussing the control of polymer nanoparticle size.", "topic_narrative": "I am looking for articles focusing on how to control the size of polymer nanoparticles upon production. Relevant article should focus on the production aspect of the polymer nanoparticle. Articles limited to the function and outcome of the nanoparticle size are not considered relevant. Additionally, articles talking about the size of nanoparticles after production are not considered relevant either. Article should describe how to control the size; those limited to the production of nanoparticle with only one size are not considered as relevant. Relevant documents will describe polymer nanoparticles, not nanoparticles made off other materials."}, {"lang": "zho", "source": "human translation", "topic_title": "\u805a\u5408\u7269\u7eb3\u7c73\u9897\u7c92\u5c3a\u5bf8\u63a7\u5236", "topic_description": "\u6211\u60f3\u8981\u627e\u4e0e\u63a7\u5236\u805a\u5408\u7269\u7eb3\u7c73\u9897\u7c92\u5927\u5c0f\u6709\u5173\u7684\u6587\u7ae0\u3002", "topic_narrative": ""}, {"lang": "zho", "source": "google translation", "topic_title": "\u805a\u5408\u7269\u7eb3\u7c73\u9897\u7c92\u5c3a\u5bf8\u63a7\u5236", "topic_description": "\u6211\u6b63\u5728\u5bfb\u627e\u8ba8\u8bba\u805a\u5408\u7269\u7eb3\u7c73\u9897\u7c92\u5c3a\u5bf8\u63a7\u5236\u7684\u6587\u7ae0\u3002", "topic_narrative": "\u6211\u6b63\u5728\u5bfb\u627e\u5173\u6ce8\u5982\u4f55\u5728\u751f\u4ea7\u65f6\u63a7\u5236\u805a\u5408\u7269\u7eb3\u7c73\u9897\u7c92\u5c3a\u5bf8\u7684\u6587\u7ae0\u3002\u76f8\u5173\u6587\u7ae0\u5e94\u91cd\u70b9\u5173\u6ce8\u805a\u5408\u7269\u7eb3\u7c73\u9897\u7c92\u7684\u751f\u4ea7\u65b9\u9762\u3002\u4ec5\u9650\u4e8e\u7eb3\u7c73\u9897\u7c92\u5c3a\u5bf8\u7684\u529f\u80fd\u548c\u7ed3\u679c\u7684\u6587\u7ae0\u4e0d\u88ab\u8ba4\u4e3a\u662f\u76f8\u5173\u7684\u3002\u6b64\u5916\uff0c\u8c08\u8bba\u751f\u4ea7\u540e\u7eb3\u7c73\u9897\u7c92\u5c3a\u5bf8\u7684\u6587\u7ae0\u4e5f\u4e0d\u88ab\u8ba4\u4e3a\u662f\u76f8\u5173\u7684\u3002\u6587\u7ae0\u5e94\u63cf\u8ff0\u5982\u4f55\u63a7\u5236\u5927\u5c0f\uff1b\u90a3\u4e9b\u4ec5\u9650\u4e8e\u751f\u4ea7\u4ec5\u4e00\u79cd\u5c3a\u5bf8\u7684\u7eb3\u7c73\u9897\u7c92\u7684\u6280\u672f\u4e0d\u88ab\u8ba4\u4e3a\u662f\u76f8\u5173\u7684\u3002\u76f8\u5173\u6587\u4ef6\u5c06\u63cf\u8ff0\u805a\u5408\u7269\u7eb3\u7c73\u9897\u7c92\uff0c\u800c\u4e0d\u662f\u7531\u5176\u4ed6\u6750\u6599\u5236\u6210\u7684\u7eb3\u7c73\u9897\u7c92\u3002"}]}
{"topic_id": "40", "languages_with_qrels": [], "topics": [{"lang": "eng", "source": "original", "topic_title": "Hematopoietic stem cells", "topic_description": "I wish to find articles on the biological characteristics of hematopoietic stem cells.", "topic_narrative": "Articles describing the biological aspects of hematopoietic stem cells, either about their basic biological characterization or about their medical application in the clinical context are considered relecant. Anything that includes details about this cell type itself would be considered relevant, but merely mentioning the cell types without any details are not relevant."}, {"lang": "zho", "source": "human translation", "topic_title": "\u9020\u8840\u5e72\u7ec6\u80de", "topic_description": "\u6211\u5e0c\u671b\u627e\u5230\u5173\u4e8e\u9020\u8840\u5e72\u7ec6\u80de\u751f\u7269\u7279\u5f81\u7684\u7814\u7a76\u6587\u7ae0\u3002", "topic_narrative": ""}, {"lang": "zho", "source": "google translation", "topic_title": "\u9020\u8840\u5e72\u7ec6\u80de", "topic_description": "\u6211\u5e0c\u671b\u627e\u5230\u6709\u5173\u9020\u8840\u5e72\u7ec6\u80de\u751f\u7269\u5b66\u7279\u6027\u7684\u6587\u7ae0\u3002", "topic_narrative": "\u63cf\u8ff0\u9020\u8840\u5e72\u7ec6\u80de\u751f\u7269\u5b66\u65b9\u9762\u7684\u6587\u7ae0\uff0c\u65e0\u8bba\u662f\u5173\u4e8e\u5b83\u4eec\u7684\u57fa\u672c\u751f\u7269\u5b66\u7279\u5f81\u8fd8\u662f\u5173\u4e8e\u5b83\u4eec\u5728\u4e34\u5e8a\u80cc\u666f\u4e0b\u7684\u533b\u5b66\u5e94\u7528\uff0c\u90fd\u88ab\u8ba4\u4e3a\u662f\u76f8\u5173\u7684\u3002\u4efb\u4f55\u5305\u542b\u6709\u5173\u8be5\u7ec6\u80de\u7c7b\u578b\u672c\u8eab\u7684\u8be6\u7ec6\u4fe1\u606f\u7684\u5185\u5bb9\u90fd\u5c06\u88ab\u89c6\u4e3a\u76f8\u5173\uff0c\u4f46\u4ec5\u63d0\u53ca\u6ca1\u6709\u4efb\u4f55\u8be6\u7ec6\u4fe1\u606f\u7684\u7ec6\u80de\u7c7b\u578b\u662f\u4e0d\u76f8\u5173\u7684\u3002"}]}
{"topic_id": "41", "languages_with_qrels": [], "topics": [{"lang": "eng", "source": "original", "topic_title": "Pure gold nanoparticle production", "topic_description": "I am looking for articles discussing the production of pure gold nanoparticles.", "topic_narrative": "Only articles related to the production process of pure gold nano particles are considered relevant. Documents discussing the production of nanoparticles made off materials other than pure gold are not considered relevant. Additionally, documents focusing on the property or applications of the pure gold nano particles rather than their production are not considered relevant."}, {"lang": "zho", "source": "human translation", "topic_title": "\u7eaf\u91d1\u7eb3\u7c73\u9897\u7c92\u7684\u5236\u5907", "topic_description": "\u4e0e\u7eaf\u91d1\u7eb3\u7c73\u9897\u7c92\u7684\u5236\u4f5c\u5de5\u827a\u76f8\u5173\u7684\u6587\u7ae0\u3002", "topic_narrative": ""}, {"lang": "zho", "source": "google translation", "topic_title": "\u7eaf\u91d1\u7eb3\u7c73\u9897\u7c92\u751f\u4ea7", "topic_description": "\u6211\u6b63\u5728\u5bfb\u627e\u8ba8\u8bba\u7eaf\u91d1\u7eb3\u7c73\u9897\u7c92\u751f\u4ea7\u7684\u6587\u7ae0\u3002", "topic_narrative": "\u53ea\u6709\u4e0e\u7eaf\u91d1\u7eb3\u7c73\u7c92\u5b50\u7684\u751f\u4ea7\u8fc7\u7a0b\u76f8\u5173\u7684\u6587\u7ae0\u624d\u88ab\u8ba4\u4e3a\u662f\u76f8\u5173\u7684\u3002\u8ba8\u8bba\u7531\u7eaf\u91d1\u4ee5\u5916\u7684\u6750\u6599\u5236\u6210\u7684\u7eb3\u7c73\u9897\u7c92\u7684\u751f\u4ea7\u7684\u6587\u4ef6\u88ab\u8ba4\u4e3a\u4e0d\u76f8\u5173\u3002\u6b64\u5916\uff0c\u5173\u6ce8\u7eaf\u91d1\u7eb3\u7c73\u9897\u7c92\u7684\u7279\u6027\u6216\u5e94\u7528\u800c\u4e0d\u662f\u5176\u751f\u4ea7\u7684\u6587\u4ef6\u88ab\u8ba4\u4e3a\u4e0d\u76f8\u5173\u3002"}]}