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train · 48.9k rows

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ID stringlengths 13 17	question stringlengths 88 1.13k	answer stringlengths 6 156	reference_sequence stringlengths 4.1k 4.1k	variant_sequence stringlengths 4.1k 4.1k
Task1_train_48600	Located on Chromosome 22, this mutation has been observed. What is its biological consequence — is it benign or pathogenic, and which disease is associated if any?	Benign	CCCACAAGGAGCCTTGGGGGATGTGGACCAGGGCTGGATCATGTGCAGGTGGGCGGTTGACAGGCATGGACTGAGCTGCTGCTGGACCATTCTCCTTGGTGCTGAAGGAAGGCAAAGGAGAAGGGCAGAAAGAAATGAAAGAGCCTTGGCTTTCTAGCTAGAGCAACTTCATCAATGTGAAATAGTCACCTTAAGAACCAGTTAATACAGAAAAGCACTGTACTATAGAAACAGGAAGTACATTCGTGGCTGCCTAGATCCAGGGGTGTGGGAGTTGGGAAAGACAGAGGAGTGACTACTAGTGGGGTTTCTTTGAGGGG...	CCCACAAGGAGCCTTGGGGGATGTGGACCAGGGCTGGATCATGTGCAGGTGGGCGGTTGACAGGCATGGACTGAGCTGCTGCTGGACCATTCTCCTTGGTGCTGAAGGAAGGCAAAGGAGAAGGGCAGAAAGAAATGAAAGAGCCTTGGCTTTCTAGCTAGAGCAACTTCATCAATGTGAAATAGTCACCTTAAGAACCAGTTAATACAGAAAAGCACTGTACTATAGAAACAGGAAGTACATTCGTGGCTGCCTAGATCCAGGGGTGTGGGAGTTGGGAAAGACAGAGGAGTGACTACTAGTGGGGTTTCTTTGAGGGG...
Task1_train_48601	A genomic variant on Chromosome 22 is under review. What is the biological outcome — benign or pathogenic?	Benign	ATTGACATAAAGATTGAGCATGTAATACACAAAGTTCCCACATCATTCTCTTCTCTCATCCTACCTTATAATTCCACCTAATATTCACATCTTACATTACTGTGTTATATTTGCTAAAATTAATGGGCAAATATTGATACATTAGTATCTAAAGTCTGTCATTCACATAGTGTTCTTTCTTCCTGTTACACATTTCTATGAATTTTGAAATATTTACTATGTTATGTTTACCATTTCGAACTCATAAGGAATATTCTCACTGCTCCAAAAATTCCCTCTTCTTTACTTATGAATCTCTGTCCTCTTCTCCAGAAATCATG...	ATTGACATAAAGATTGAGCATGTAATACACAAAGTTCCCACATCATTCTCTTCTCTCATCCTACCTTATAATTCCACCTAATATTCACATCTTACATTACTGTGTTATATTTGCTAAAATTAATGGGCAAATATTGATACATTAGTATCTAAAGTCTGTCATTCACATAGTGTTCTTTCTTCCTGTTACACATTTCTATGAATTTTGAAATATTTACTATGTTATGTTTACCATTTCGAACTCATAAGGAATATTCTCACTGCTCCAAAAATTCCCTCTTCTTTACTTATGAATCTCTGTCCTCTTCTCCAGAAATCATG...
Task1_train_48602	Assess the clinical impact of this variant found on Chromosome 22. State whether it’s pathogenic or benign, and the disease if applicable.	Benign	TCCACCTAATATTCACATCTTACATTACTGTGTTATATTTGCTAAAATTAATGGGCAAATATTGATACATTAGTATCTAAAGTCTGTCATTCACATAGTGTTCTTTCTTCCTGTTACACATTTCTATGAATTTTGAAATATTTACTATGTTATGTTTACCATTTCGAACTCATAAGGAATATTCTCACTGCTCCAAAAATTCCCTCTTCTTTACTTATGAATCTCTGTCCTCTTCTCCAGAAATCATGCCAACTATGGATATTTTTACTGTTCCCTTGGTTTTGCCTTTTCTAGAATGTCATATAGTTGGAGTCATATAT...	TCCACCTAATATTCACATCTTACATTACTGTGTTATATTTGCTAAAATTAATGGGCAAATATTGATACATTAGTATCTAAAGTCTGTCATTCACATAGTGTTCTTTCTTCCTGTTACACATTTCTATGAATTTTGAAATATTTACTATGTTATGTTTACCATTTCGAACTCATAAGGAATATTCTCACTGCTCCAAAAATTCCCTCTTCTTTACTTATGAATCTCTGTCCTCTTCTCCAGAAATCATGCCAACTATGGATATTTTTACTGTTCCCTTGGTTTTGCCTTTTCTAGAATGTCATATAGTTGGAGTCATATAT...
Task1_train_48603	A genomic change on Chromosome 22 is noted. Classify this variant as benign or pathogenic, and name the disease if relevant.	Benign	TCTTTCTTCCTGTTACACATTTCTATGAATTTTGAAATATTTACTATGTTATGTTTACCATTTCGAACTCATAAGGAATATTCTCACTGCTCCAAAAATTCCCTCTTCTTTACTTATGAATCTCTGTCCTCTTCTCCAGAAATCATGCCAACTATGGATATTTTTACTGTTCCCTTGGTTTTGCCTTTTCTAGAATGTCATATAGTTGGAGTCATATATTAGGTTGGTGCAAAAGTAATTGCGGTTTTCCCATTCTTTAAATGCCAAAAACCACAATTACTTTTGCACCAACCAAATATTATGCAGCTTTTTCAGCTGAA...	TCTTTCTTCCTGTTACACATTTCTATGAATTTTGAAATATTTACTATGTTATGTTTACCATTTCGAACTCATAAGGAATATTCTCACTGCTCCAAAAATTCCCTCTTCTTTACTTATGAATCTCTGTCCTCTTCTCCAGAAATCATGCCAACTATGGATATTTTTACTGTTCCCTTGGTTTTGCCTTTTCTAGAATGTCATATAGTTGGAGTCATATATTAGGTTGGTGCAAAAGTAATTGCGGTTTTCCCATTCTTTAAATGCCAAAAACCACAATTACTTTTGCACCAACCAAATATTATGCAGCTTTTTCAGCTGAA...
Task1_train_48604	A variant found on Chromosome 22 is being studied. Please analyze its biological impact: is it benign or pathogenic, and what condition might it cause?	Benign	CCCCACTCGCTGTAACTTGCGGTCTACGAAGAGGAAAGTCAGCGGCACCGTGGTGGCAGAGAGGCGGCCTCCATCCCTCAAACTCACAGTCCAGAATCCAAGCTCTGTGGTCAGCTGGATCCTCCCTTTGCGGTGAACAGATTCTCTGCAGACTCCCAGGTCCCATTCTGTGCTTGTTCCCACGTCCACCTCCCAGCAGTGGCGGCCACAGGTAAAGCGAGGGGAGCCCAGGATGCAAACGGACACGTCAAATCTCTCGGCAAGGTCTTGCCGATTCTGTCTGATGCGCCCACTTCGGACGCTCCTGAGGTCGTCAGAAA...	CCCCACTCGCTGTAACTTGCGGTCTACGAAGAGGAAAGTCAGCGGCACCGTGGTGGCAGAGAGGCGGCCTCCATCCCTCAAACTCACAGTCCAGAATCCAAGCTCTGTGGTCAGCTGGATCCTCCCTTTGCGGTGAACAGATTCTCTGCAGACTCCCAGGTCCCATTCTGTGCTTGTTCCCACGTCCACCTCCCAGCAGTGGCGGCCACAGGTAAAGCGAGGGGAGCCCAGGATGCAAACGGACACGTCAAATCTCTCGGCAAGGTCTTGCCGATTCTGTCTGATGCGCCCACTTCGGACGCTCCTGAGGTCGTCAGAAA...
Task1_train_48605	Here is a mutation located on Chromosome 22. Determine whether it’s benign or pathogenic. If the latter, what disease does it cause?	Benign	CCTCCATCCCTCAAACTCACAGTCCAGAATCCAAGCTCTGTGGTCAGCTGGATCCTCCCTTTGCGGTGAACAGATTCTCTGCAGACTCCCAGGTCCCATTCTGTGCTTGTTCCCACGTCCACCTCCCAGCAGTGGCGGCCACAGGTAAAGCGAGGGGAGCCCAGGATGCAAACGGACACGTCAAATCTCTCGGCAAGGTCTTGCCGATTCTGTCTGATGCGCCCACTTCGGACGCTCCTGAGGTCGTCAGAAATGAGGAGGAAGTTGTTGGCTGTGTTGGCATCCAAGGTCATATCCACTGTGAAAAGGAAAAAAAGTTG...	CCTCCATCCCTCAAACTCACAGTCCAGAATCCAAGCTCTGTGGTCAGCTGGATCCTCCCTTTGCGGTGAACAGATTCTCTGCAGACTCCCAGGTCCCATTCTGTGCTTGTTCCCACGTCCACCTCCCAGCAGTGGCGGCCACAGGTAAAGCGAGGGGAGCCCAGGATGCAAACGGACACGTCAAATCTCTCGGCAAGGTCTTGCCGATTCTGTCTGATGCGCCCACTTCGGACGCTCCTGAGGTCGTCAGAAATGAGGAGGAAGTTGTTGGCTGTGTTGGCATCCAAGGTCATATCCACTGTGAAAAGGAAAAAAAGTTG...
Task1_train_48606	Consider a variant on Chromosome 22. Determine its clinical classification and disease relevance.	Benign	CTCCATTCCCAACTCTTCCCAACCCTGGGGTAAGGTTGTTTGTACAATGGGTGCCAATATTCACCGTGCATTAGAATTACCAGGCCCATTTTAATGTTAGAGTCCTGGGAACCTTTGCTAGAGAGAAATTCAAATTCAGTTGCTCTATGTTTTTGCTACTCAGCAAAGTCCCCAAGCCAGTGGGATCAATCCTGAGACTTCCCAGTTCAGCATCTGCATTTTAACAAGATCCCCAGGTAATCTGAGCACACTAAGTTTAGAGAATCCCTTGTCTAACCCATGACATAGACATCGGGTTTTTGTTTGTTTTTGTTTTTGAC...	CTCCATTCCCAACTCTTCCCAACCCTGGGGTAAGGTTGTTTGTACAATGGGTGCCAATATTCACCGTGCATTAGAATTACCAGGCCCATTTTAATGTTAGAGTCCTGGGAACCTTTGCTAGAGAGAAATTCAAATTCAGTTGCTCTATGTTTTTGCTACTCAGCAAAGTCCCCAAGCCAGTGGGATCAATCCTGAGACTTCCCAGTTCAGCATCTGCATTTTAACAAGATCCCCAGGTAATCTGAGCACACTAAGTTTAGAGAATCCCTTGTCTAACCCATGACATAGACATCGGGTTTTTGTTTGTTTTTGTTTTTGAC...
Task1_train_48607	Given this context: Chromosome 22 — does this variant present pathogenic behavior, and if so, what disease does it relate to?	Benign	CTCACCAAAAAATAAAAAAATAAAAAAATAAAAAAAATTACATCCTTCTCCAGCCTTGGAAGTGAATACCAAATTGACTGCCACCACTCTTACACTCCTAGACTGGGGATCCAGGGTGACTGGTTTCCAACTCTGAGGCAGCACTCAGACGGCCTTTGTTGAATTCATTAATTACGAATTTCTCTCATTCATCCCCCCAAGTCATAACCCCCATTTCTAGGCATCTAAGAGGAAAAACACACACACAGGCATGGGCTCACCTCTTCTGCTGGAAGCTCCTCTGTCCTCCAGCTGCTTCCACTGGGCGCTCAGGTCTTGTG...	CTCACCAAAAAATAAAAAAATAAAAAAATAAAAAAAATTACATCCTTCTCCAGCCTTGGAAGTGAATACCAAATTGACTGCCACCACTCTTACACTCCTAGACTGGGGATCCAGGGTGACTGGTTTCCAACTCTGAGGCAGCACTCAGACGGCCTTTGTTGAATTCATTAATTACGAATTTCTCTCATTCATCCCCCCAAGTCATAACCCCCATTTCTAGGCATCTAAGAGGAAAAACACACACACAGGCATGGGCTCACCTCTTCTGCTGGAAGCTCCTCTGTCCTCCAGCTGCTTCCACTGGGCGCTCAGGTCTTGTG...
Task1_train_48608	Chromosome 22 carries this variant. Does this mutation lead to a specific disease, or is it non-pathogenic?	Benign	GCCTGCAGTGAGCGGAGATCGCGCCACTGCACTCCAGCCTGGGTGACAGAGCAAGACTCTGTCTCAAAAAAAAAAAAAAAAAGAAAATAGACAGATGCTGAGATGTTTCAGTCACTACTCCTCAGAGCAGGAGTCAAGCAAACAATGGCCCCTGGGCTAATCCAGCCCACAGTCAGTTTCTGAATGGCCCACGAGCCAAGAATGTTTTTTTACATTTTTGCATTGTTAAATAATGGTAAACAATCTAAGTAAGCATAATATTTTGTGAAATGTGAAATTGTAAACTTGTGAAATTGTATGATTCAAATTTCATTGTCTGG...	GCCTGCAGTGAGCGGAGATCGCGCCACTGCACTCCAGCCTGGGTGACAGAGCAAGACTCTGTCTCAAAAAAAAAAAAAAAAAGAAAATAGACAGATGCTGAGATGTTTCAGTCACTACTCCTCAGAGCAGGAGTCAAGCAAACAATGGCCCCTGGGCTAATCCAGCCCACAGTCAGTTTCTGAATGGCCCACGAGCCAAGAATGTTTTTTTACATTTTTGCATTGTTAAATAATGGTAAACAATCTAAGTAAGCATAATATTTTGTGAAATGTGAAATTGTAAACTTGTGAAATTGTATGATTCAAATTTCATTGTCTGG...
Task1_train_48609	The following genetic variant occurs on Chromosome 22. Classify its clinical effect — pathogenic or benign — and list any associated condition.	Benign	CCTTTCTTTTTTTATATTAGAGAATATAATAGAACTAAGAAATCTCAATCAGGTGTGGCAGCTCACACCTGTAATCTCAGCACTTTGGGAGGCCAAGGCAGGAGGATCACTTGAGCCAGGGGTTCTAGACCAGCCAGGGCAACATGGTGAGACCCCCATCTCTACAAAAAATAGAAAAAGTTCGTTGGGCATGGTGGCATGTGCCTGTGGTCCCAGCTTCTTGGGAGGCTCAGGTGGATCACCTGAGCCCATGTAGTTAACGTTACAGTAAGCCATGATTATGCCACTGCATTCTAGCAGCAGTGGGCGACAGAGACCCA...	CCTTTCTTTTTTTATATTAGAGAATATAATAGAACTAAGAAATCTCAATCAGGTGTGGCAGCTCACACCTGTAATCTCAGCACTTTGGGAGGCCAAGGCAGGAGGATCACTTGAGCCAGGGGTTCTAGACCAGCCAGGGCAACATGGTGAGACCCCCATCTCTACAAAAAATAGAAAAAGTTCGTTGGGCATGGTGGCATGTGCCTGTGGTCCCAGCTTCTTGGGAGGCTCAGGTGGATCACCTGAGCCCATGTAGTTAACGTTACAGTAAGCCATGATTATGCCACTGCATTCTAGCAGCAGTGGGCGACAGAGACCCA...
Task1_train_48610	Here is a mutation located on Chromosome 22. Determine whether it’s benign or pathogenic. If the latter, what disease does it cause?	Benign	AAAATGATACAATATATATTGTTTCCTTAAAGCAGTCAATACAATGCATAAATTTCTAGAGAAATCAGTAAAAAAAAAAAAAGTTCATAACAAAGGTAGTAACATTAGGAATAAAAGAGGGCTCAACACTGCAGGTTCTTAAAGGCAAAAGTTAGTGAAGCATTGTTTTTGGTTGTGAATCTTGCCCTAAAAACATTATAATTCCACATGATCCTCCCCTTCCTTTTCCTGTTGCAACGATGTGATGAACCAAATTTGCTTATGCAGATGACAATACTCTCAGAAAATGGTGGCAGAGAAATAAAATGAAGGGAATATGG...	AAAATGATACAATATATATTGTTTCCTTAAAGCAGTCAATACAATGCATAAATTTCTAGAGAAATCAGTAAAAAAAAAAAAAGTTCATAACAAAGGTAGTAACATTAGGAATAAAAGAGGGCTCAACACTGCAGGTTCTTAAAGGCAAAAGTTAGTGAAGCATTGTTTTTGGTTGTGAATCTTGCCCTAAAAACATTATAATTCCACATGATCCTCCCCTTCCTTTTCCTGTTGCAACGATGTGATGAACCAAATTTGCTTATGCAGATGACAATACTCTCAGAAAATGGTGGCAGAGAAATAAAATGAAGGGAATATGG...
Task1_train_48611	A variant was discovered on Chromosome 22. What is its functional impact — neutral or pathogenic? State the disease if pathogenic.	Benign	AAGAAACAGAGGCTGTGGGTGGGTAGAGGGTCTTGACTAGGGTAGGGACAGAGGGTGCGTCTTAAGGCTCAGCTAGGGACAGCTTCATCCAGGAAGTAGTCAGCAATTGGGGGCCAAGCTGCAAGGAGGAAGAGGTGGGGAGAGAGAATGGAGAGAGAGGTGTTCAGTGATCAAATGCCTGGCCTGGCCTGTTTCCTCAGGAGACACCCCTGGGAGTCTGGGAGCCTCTCCCCCGGGCTGCTATCCAACAGGGTGCAAGTAATCCCCCCTTACACACACTAAGAACCCAGGGTGAGTGTCAAATTATATGTTAGCTAAGA...	AAGAAACAGAGGCTGTGGGTGGGTAGAGGGTCTTGACTAGGGTAGGGACAGAGGGTGCGTCTTAAGGCTCAGCTAGGGACAGCTTCATCCAGGAAGTAGTCAGCAATTGGGGGCCAAGCTGCAAGGAGGAAGAGGTGGGGAGAGAGAATGGAGAGAGAGGTGTTCAGTGATCAAATGCCTGGCCTGGCCTGTTTCCTCAGGAGACACCCCTGGGAGTCTGGGAGCCTCTCCCCCGGGCTGCTATCCAACAGGGTGCAAGTAATCCCCCCTTACACACACTAAGAACCCAGGGTGAGTGTCAAATTATATGTTAGCTAAGA...
Task1_train_48612	This alteration occurs on Chromosome 22. Is it associated with a disease or is it a benign variant?	Benign	GGACAGCTTCATCCAGGAAGTAGTCAGCAATTGGGGGCCAAGCTGCAAGGAGGAAGAGGTGGGGAGAGAGAATGGAGAGAGAGGTGTTCAGTGATCAAATGCCTGGCCTGGCCTGTTTCCTCAGGAGACACCCCTGGGAGTCTGGGAGCCTCTCCCCCGGGCTGCTATCCAACAGGGTGCAAGTAATCCCCCCTTACACACACTAAGAACCCAGGGTGAGTGTCAAATTATATGTTAGCTAAGAAATGAAGAGAGGGAGCAGGATTTCTGGTTGACGGTGAGGATATTTATTAAGGGTTTACTGGTACAAGGAGAGGGGC...	GGACAGCTTCATCCAGGAAGTAGTCAGCAATTGGGGGCCAAGCTGCAAGGAGGAAGAGGTGGGGAGAGAGAATGGAGAGAGAGGTGTTCAGTGATCAAATGCCTGGCCTGGCCTGTTTCCTCAGGAGACACCCCTGGGAGTCTGGGAGCCTCTCCCCCGGGCTGCTATCCAACAGGGTGCAAGTAATCCCCCCTTACACACACTAAGAACCCAGGGTGAGTGTCAAATTATATGTTAGCTAAGAAATGAAGAGAGGGAGCAGGATTTCTGGTTGACGGTGAGGATATTTATTAAGGGTTTACTGGTACAAGGAGAGGGGC...
Task1_train_48613	A mutation located on Chromosome 22 is being studied. Determine whether it’s pathogenic or benign, and specify the linked disease.	Benign	GAGGTGTTCAGTGATCAAATGCCTGGCCTGGCCTGTTTCCTCAGGAGACACCCCTGGGAGTCTGGGAGCCTCTCCCCCGGGCTGCTATCCAACAGGGTGCAAGTAATCCCCCCTTACACACACTAAGAACCCAGGGTGAGTGTCAAATTATATGTTAGCTAAGAAATGAAGAGAGGGAGCAGGATTTCTGGTTGACGGTGAGGATATTTATTAAGGGTTTACTGGTACAAGGAGAGGGGCTGGATGATTTGGGGTGGGAGGGGATCTCTGTTCTGGGATCCTGCAGCTCCAGGCCCCCATGGGTGGGGTGAGGGTCAGGG...	GAGGTGTTCAGTGATCAAATGCCTGGCCTGGCCTGTTTCCTCAGGAGACACCCCTGGGAGTCTGGGAGCCTCTCCCCCGGGCTGCTATCCAACAGGGTGCAAGTAATCCCCCCTTACACACACTAAGAACCCAGGGTGAGTGTCAAATTATATGTTAGCTAAGAAATGAAGAGAGGGAGCAGGATTTCTGGTTGACGGTGAGGATATTTATTAAGGGTTTACTGGTACAAGGAGAGGGGCTGGATGATTTGGGGTGGGAGGGGATCTCTGTTCTGGGATCCTGCAGCTCCAGGCCCCCATGGGTGGGGTGAGGGTCAGGG...
Task1_train_48614	A mutation on Chromosome 22 is under examination. Does this mutation cause a disorder, or is it a benign change?	Benign	TACACACACTAAGAACCCAGGGTGAGTGTCAAATTATATGTTAGCTAAGAAATGAAGAGAGGGAGCAGGATTTCTGGTTGACGGTGAGGATATTTATTAAGGGTTTACTGGTACAAGGAGAGGGGCTGGATGATTTGGGGTGGGAGGGGATCTCTGTTCTGGGATCCTGCAGCTCCAGGCCCCCATGGGTGGGGTGAGGGTCAGGGACCTAAGAACATTCTTCAGGGGCCACTGTCTTCTCCACAGTGCTCTCTTGTGTGTGACCTTACAGCTGTAGCTGCTGCAGGACCTCCACTGGTCGGGTGTCAGGCTCAGGTCGC...	TACACACACTAAGAACCCAGGGTGAGTGTCAAATTATATGTTAGCTAAGAAATGAAGAGAGGGAGCAGGATTTCTGGTTGACGGTGAGGATATTTATTAAGGGTTTACTGGTACAAGGAGAGGGGCTGGATGATTTGGGGTGGGAGGGGATCTCTGTTCTGGGATCCTGCAGCTCCAGGCCCCCATGGGTGGGGTGAGGGTCAGGGACCTAAGAACATTCTTCAGGGGCCACTGTCTTCTCCACAGTGCTCTCTTGTGTGTGACCTTACAGCTGTAGCTGCTGCAGGACCTCCACTGGTCGGGTGTCAGGCTCAGGTCGC...
Task1_train_48615	The following genetic variant occurs on Chromosome 22. Classify its clinical effect — pathogenic or benign — and list any associated condition.	Benign	GGAGCAGGATTTCTGGTTGACGGTGAGGATATTTATTAAGGGTTTACTGGTACAAGGAGAGGGGCTGGATGATTTGGGGTGGGAGGGGATCTCTGTTCTGGGATCCTGCAGCTCCAGGCCCCCATGGGTGGGGTGAGGGTCAGGGACCTAAGAACATTCTTCAGGGGCCACTGTCTTCTCCACAGTGCTCTCTTGTGTGTGACCTTACAGCTGTAGCTGCTGCAGGACCTCCACTGGTCGGGTGTCAGGCTCAGGTCGCTTCTGGCTGTGTGCTTGTTGCTCTGTTTGGAGGTCTTGGTGACTTCCGTACCCTGGGTGAC...	GGAGCAGGATTTCTGGTTGACGGTGAGGATATTTATTAAGGGTTTACTGGTACAAGGAGAGGGGCTGGATGATTTGGGGTGGGAGGGGATCTCTGTTCTGGGATCCTGCAGCTCCAGGCCCCCATGGGTGGGGTGAGGGTCAGGGACCTAAGAACATTCTTCAGGGGCCACTGTCTTCTCCACAGTGCTCTCTTGTGTGTGACCTTACAGCTGTAGCTGCTGCAGGACCTCCACTGGTCGGGTGTCAGGCTCAGGTCGCTTCTGGCTGTGTGCTTGTTGCTCTGTTTGGAGGTCTTGGTGACTTCCGTACCCTGGGTGAC...
Task1_train_48616	This alteration on Chromosome 22 may affect genome function. Does it lead to a disease or is it benign?	Benign	TCCCACATCAAGGAACTGGAGCCCAAGCTGAAGAAGATTCTACAGATGAACCCAAGGATGCGGAAGTTCCAAGGTAAGGAATCTGTATACCCTGCCCCCTTCCCAAGACCAGACCAGGAAAAATCATCTGTGCAGTTGGCCCCTCATTCCACATGGGGATTAGCTGCTGTCTGGCACCTAAAATTGAGATGCTTCATCATCACATTCTCAGCCCTGACAACACATAGAATCACCTGGTGATGTCAAAAACAAAAACAAACAAAAACCCGATGTCTATGTCATGGGTTAGACAAGGGATTCTCTAAACTTAGTGTGCTCAG...	TCCCACATCAAGGAACTGGAGCCCAAGCTGAAGAAGATTCTACAGATGAACCCAAGGATGCGGAAGTTCCAAGGTAAGGAATCTGTATACCCTGCCCCCTTCCCAAGACCAGACCAGGAAAAATCATCTGTGCAGTTGGCCCCTCATTCCACATGGGGATTAGCTGCTGTCTGGCACCTAAAATTGAGATGCTTCATCATCACATTCTCAGCCCTGACAACACATAGAATCACCTGGTGATGTCAAAAACAAAAACAAACAAAAACCCGATGTCTATGTCATGGGTTAGACAAGGGATTCTCTAAACTTAGTGTGCTCAG...
Task1_train_48617	A mutation on Chromosome 22 has been found. Is it harmful or harmless? What disease, if any, does it cause?	Benign	GTACTGTCCTGTAGTGTATAACTTTAGGATCTTTATTAGTCGATTTCCTCTAAACTACAGCTAAGCGAAATCCAGAAGTTTAAAGTATAATCTAGTTATCTTTTGTTTTGGAAATGCTTTTCAGCAGCTTATGAAAACACCTTGAGTCTGGGTCAGGTTCGGTGCATTGGCTTGGAGTTTACACCCTCAGCTGGGAGGGGAAAAAGATAACGCCAGCAGCTGAGAAAGAAAAACCTGTTTGAGTAAATACCATAGCTGAACATTTATGTTTCAGAATGAATCTGGATATACACCAAATAACTTTTTTGGTCAGAAAGGAG...	GTACTGTCCTGTAGTGTATAACTTTAGGATCTTTATTAGTCGATTTCCTCTAAACTACAGCTAAGCGAAATCCAGAAGTTTAAAGTATAATCTAGTTATCTTTTGTTTTGGAAATGCTTTTCAGCAGCTTATGAAAACACCTTGAGTCTGGGTCAGGTTCGGTGCATTGGCTTGGAGTTTACACCCTCAGCTGGGAGGGGAAAAAGATAACGCCAGCAGCTGAGAAAGAAAAACCTGTTTGAGTAAATACCATAGCTGAACATTTATGTTTCAGAATGAATCTGGATATACACCAAATAACTTTTTTGGTCAGAAAGGAG...
Task1_train_48618	This alteration on Chromosome 22 may affect genome function. Does it lead to a disease or is it benign?	Benign	TATGCAGGTAGGGGAAAACCACTAGAGGGCCTAAGGGATTTCCACTGAGAATGACCAATACAAATACAGACTTAGAGTTGCTTACCCACCTGGTCAGAAGTACATGCCTAGCTCTTGTCCTAGAATCTTTCTTGCCCCAAACAAACAAACAAACATAAACACAGACACACGCAGCATGCATACACTCACATTCAGACACCTCTATTTATCCCTTTAACAGAGTCTGCCTTATTCTGGGTTCCTGAAGGCTTAAGAAAGAAAACTTTCTGCCTAAGCAATTCACAAGGGCTTTACAATTCCAGTGTGTACTGTCTTTCCCT...	TATGCAGGTAGGGGAAAACCACTAGAGGGCCTAAGGGATTTCCACTGAGAATGACCAATACAAATACAGACTTAGAGTTGCTTACCCACCTGGTCAGAAGTACATGCCTAGCTCTTGTCCTAGAATCTTTCTTGCCCCAAACAAACAAACAAACATAAACACAGACACACGCAGCATGCATACACTCACATTCAGACACCTCTATTTATCCCTTTAACAGAGTCTGCCTTATTCTGGGTTCCTGAAGGCTTAAGAAAGAAAACTTTCTGCCTAAGCAATTCACAAGGGCTTTACAATTCCAGTGTGTACTGTCTTTCCCT...
Task1_train_48619	A mutation located on Chromosome 22 is being studied. Determine whether it’s pathogenic or benign, and specify the linked disease.	Benign	TGGAGCCAAATACACTATCAAGACTCAAACCCTGAGCACTTACCCGGGAGAGCACGTTGCCAAGGCCTTGAGAGTTTTGAACAAAATGGTTGGAAATCTGGAAAATAAAGCCCATTATGTCACTGTTAGGATTTTACGTGGATTGTCTTTTCAGGGAAAATGTAGTGTTCCCTATAATTTGACGAATTGTGAAGCTGTTACACCATAAAATATTCAGTGTTTAAAGGTGACCTATCATTTTATAGCCCAATCATAGGGAATCCGAGGCTCAGAGAAGTAAAGTGACTTGCCCAAGGTCACACAGGATGTTATATTTCTTT...	TGGAGCCAAATACACTATCAAGACTCAAACCCTGAGCACTTACCCGGGAGAGCACGTTGCCAAGGCCTTGAGAGTTTTGAACAAAATGGTTGGAAATCTGGAAAATAAAGCCCATTATGTCACTGTTAGGATTTTACGTGGATTGTCTTTTCAGGGAAAATGTAGTGTTCCCTATAATTTGACGAATTGTGAAGCTGTTACACCATAAAATATTCAGTGTTTAAAGGTGACCTATCATTTTATAGCCCAATCATAGGGAATCCGAGGCTCAGAGAAGTAAAGTGACTTGCCCAAGGTCACACAGGATGTTATATTTCTTT...
Task1_train_48620	Chromosome 22 is altered by this variant. Does this mutation result in a disease or is it benign?	Benign	TTTACACTCTACTGAAAGAGCTGATTCACTCAACTGTAAACTTTGCATGGGCAGAAACATGTCTTTTTGGTCTCTTGAGTCTCCAGCATGTGGGGTATCTGTCACAAAGTAGGCAATCAATACATATTTATTTGCAGAATCAAGGGCAGGATGTGGACAAGTGCTGCCACCTATTGGGAGAAACTTTATTTGACTCTAAGGATTTGGACTATGGTTATCACACAAGGACGAAACTTGATACTCTCTCTCATCTAAGTTATCATTAGTTAGACCCTCTATGGTAGCCAGCCTCCAGGATGGCCCGCAGCGATCCCTGTCTG...	TTTACACTCTACTGAAAGAGCTGATTCACTCAACTGTAAACTTTGCATGGGCAGAAACATGTCTTTTTGGTCTCTTGAGTCTCCAGCATGTGGGGTATCTGTCACAAAGTAGGCAATCAATACATATTTATTTGCAGAATCAAGGGCAGGATGTGGACAAGTGCTGCCACCTATTGGGAGAAACTTTATTTGACTCTAAGGATTTGGACTATGGTTATCACACAAGGACGAAACTTGATACTCTCTCTCATCTAAGTTATCATTAGTTAGACCCTCTATGGTAGCCAGCCTCCAGGATGGCCCGCAGCGATCCCTGTCTG...
Task1_train_48621	A variant has been detected on Chromosome 22. What is its effect — pathogenic or benign? If pathogenic, name the disease.	Benign	TTGTTTTCTAGCAAACAGGAATAGCTTCTATTTCAGTAATTTTAATTTCTCTACCAAGGACACTTCAATCAGTAAGAAAAAATATATTTACGAGTGAAATAAAAACAAGAATTATTTGGAGCACTTTTCAAAATGCAGCATTGTAAGAATAAGTAAACAATATAATTTTTAAAGGACTTCATCTTTTGTTAACCTCTCAAAAAAGTAATGAAATTAGCATTGCTGAGTGTAAATGTTTTTAAAAATGTTTTATAATGTTTTGTTATTGTTCCTCACCACTGTGTGATGAAAAACATTTTATTCTTCTAATGTCAAATAAT...	TTGTTTTCTAGCAAACAGGAATAGCTTCTATTTCAGTAATTTTAATTTCTCTACCAAGGACACTTCAATCAGTAAGAAAAAATATATTTACGAGTGAAATAAAAACAAGAATTATTTGGAGCACTTTTCAAAATGCAGCATTGTAAGAATAAGTAAACAATATAATTTTTAAAGGACTTCATCTTTTGTTAACCTCTCAAAAAAGTAATGAAATTAGCATTGCTGAGTGTAAATGTTTTTAAAAATGTTTTATAATGTTTTGTTATTGTTCCTCACCACTGTGTGATGAAAAACATTTTATTCTTCTAATGTCAAATAAT...
Task1_train_48622	A variant found on Chromosome 22 is being studied. Please analyze its biological impact: is it benign or pathogenic, and what condition might it cause?	Benign	TTTATTATTTATTTATGCAAATATTTTTTATTTGCATAAGGAAGCACTGAAAGGACACATAGGAACTAACAAAAGTCATTTCTGGGGATGGGGGTAGCAAAGCGTTGGATGAGAATGGGGCGGGAACGAGGCTTTTCAACATACATCTTTGATTTATTTATTTATTTATTTATTTATTTATTTATTGAGATGGAGTCTCACTTTGTTGCCCAGGCTGGAGTGCAATGGCGCCATCTCAGCTCACTGCAACCTCAGCCTCTCAGGTTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGGCGTGCACC...	TTTATTATTTATTTATGCAAATATTTTTTATTTGCATAAGGAAGCACTGAAAGGACACATAGGAACTAACAAAAGTCATTTCTGGGGATGGGGGTAGCAAAGCGTTGGATGAGAATGGGGCGGGAACGAGGCTTTTCAACATACATCTTTGATTTATTTATTTATTTATTTATTTATTTATTTATTGAGATGGAGTCTCACTTTGTTGCCCAGGCTGGAGTGCAATGGCGCCATCTCAGCTCACTGCAACCTCAGCCTCTCAGGTTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGGCGTGCACC...
Task1_train_48623	Located on Chromosome 22, this mutation has been observed. What is its biological consequence — is it benign or pathogenic, and which disease is associated if any?	Benign	ACCTATGTAACAAACCTGCACATTCTGCACATGTATCCCAGAACTTAAAATTAAAAAAAAAAAATTCTCCTTTGCTGTCTCCCTTTCCCCAGAAAACTTGGAGCCTATGATTGGAGAATGGTGGCATCACTGTTTGAAAGGAATCTGGGTCCCTAAATGACTACATTAGAATGTGATGTGGGTGAGCTATTATGCTCCCAAGACTATAGGGTTTACTTGCTACTACAGCAGAGCCTATTCCCCCCCTAACTAAATCAGACAGCCTGACACTTCCAAGGGGCACAGCTCCTAAAATGGGGCATCTTTACCTGTTCCCTCTC...	ACCTATGTAACAAACCTGCACATTCTGCACATGTATCCCAGAACTTAAAATTAAAAAAAAAAAATTCTCCTTTGCTGTCTCCCTTTCCCCAGAAAACTTGGAGCCTATGATTGGAGAATGGTGGCATCACTGTTTGAAAGGAATCTGGGTCCCTAAATGACTACATTAGAATGTGATGTGGGTGAGCTATTATGCTCCCAAGACTATAGGGTTTACTTGCTACTACAGCAGAGCCTATTCCCCCCCTAACTAAATCAGACAGCCTGACACTTCCAAGGGGCACAGCTCCTAAAATGGGGCATCTTTACCTGTTCCCTCTC...
Task1_train_48624	This mutation on Chromosome 22 may be significant. Is it associated with any clinical condition, or is it benign?	Benign	CCCAGAAAACTTGGAGCCTATGATTGGAGAATGGTGGCATCACTGTTTGAAAGGAATCTGGGTCCCTAAATGACTACATTAGAATGTGATGTGGGTGAGCTATTATGCTCCCAAGACTATAGGGTTTACTTGCTACTACAGCAGAGCCTATTCCCCCCCTAACTAAATCAGACAGCCTGACACTTCCAAGGGGCACAGCTCCTAAAATGGGGCATCTTTACCTGTTCCCTCTCTCAGGGTGAGTCCCTCTCTCTCCTGACTCACTCTTCTCAGGGAGTGGAGACCAACGTTCCCTATCCTTCACCTCCCACCCCTGCCCT...	CCCAGAAAACTTGGAGCCTATGATTGGAGAATGGTGGCATCACTGTTTGAAAGGAATCTGGGTCCCTAAATGACTACATTAGAATGTGATGTGGGTGAGCTATTATGCTCCCAAGACTATAGGGTTTACTTGCTACTACAGCAGAGCCTATTCCCCCCCTAACTAAATCAGACAGCCTGACACTTCCAAGGGGCACAGCTCCTAAAATGGGGCATCTTTACCTGTTCCCTCTCTCAGGGTGAGTCCCTCTCTCTCCTGACTCACTCTTCTCAGGGAGTGGAGACCAACGTTCCCTATCCTTCACCTCCCACCCCTGCCCT...
Task1_train_48625	A mutation is present on Chromosome 22. Based on this information, is the variant pathogenic or benign? Provide the disease if relevant.	Benign	CATGCAGGATTAGAAATACAGTAGCCCATTGTCACTCACTAGAGGTATTTCCTGCCCTCTTCACATGCACCCAGCTTTGCAAGTGCCACCCTAGCACACGACGTTCCACCAGATCTCACTGTGGCACCGTTAGCATTCTCTCTAAAATAGTTCTCTAAGTTGCTCTCCTTTTTTTCTTTCCACAAATGTGATGGACTCATTCTAATTCAAAATCAGGCCAACATTCTGTTCTTTATTCTATCCTTTCCTTCTGGCTGGGGACCACTCATGTCTAAGACTTCTCTCCTTTTTCTTCCCATCTAGAATCAGGCACTAGCTAA...	CATGCAGGATTAGAAATACAGTAGCCCATTGTCACTCACTAGAGGTATTTCCTGCCCTCTTCACATGCACCCAGCTTTGCAAGTGCCACCCTAGCACACGACGTTCCACCAGATCTCACTGTGGCACCGTTAGCATTCTCTCTAAAATAGTTCTCTAAGTTGCTCTCCTTTTTTTCTTTCCACAAATGTGATGGACTCATTCTAATTCAAAATCAGGCCAACATTCTGTTCTTTATTCTATCCTTTCCTTCTGGCTGGGGACCACTCATGTCTAAGACTTCTCTCCTTTTTCTTCCCATCTAGAATCAGGCACTAGCTAA...
Task1_train_48626	Here is a mutation located on Chromosome 22. Determine whether it’s benign or pathogenic. If the latter, what disease does it cause?	Benign	TTGAACTCAGGGGGTCGAAGCTGCAGTGAGCTGTGATCGTGCCACTGCACTCCAGCCTGGGTGACAGAGAAAGACCCTGTCTCAAAACAAACAAACAAAACCTCCCTCCACAGGGACACTGCTAGCAGGAAAGATGATGAAGCTTGGAGCTGCTGGAGTCATCACCTGAATCTGAGAATAAAGCTAACAGAGGAGAGCACCACAGACACGTCAAAGGACCAGCTTGAGTTACCTCCCTGGAAGTGACCATGTCTGCAGGTACTGGAAATTTCAATCATGTGAGCCAATAAATTCCCCTCTTCTGGGGAAACACATGGAAA...	TTGAACTCAGGGGGTCGAAGCTGCAGTGAGCTGTGATCGTGCCACTGCACTCCAGCCTGGGTGACAGAGAAAGACCCTGTCTCAAAACAAACAAACAAAACCTCCCTCCACAGGGACACTGCTAGCAGGAAAGATGATGAAGCTTGGAGCTGCTGGAGTCATCACCTGAATCTGAGAATAAAGCTAACAGAGGAGAGCACCACAGACACGTCAAAGGACCAGCTTGAGTTACCTCCCTGGAAGTGACCATGTCTGCAGGTACTGGAAATTTCAATCATGTGAGCCAATAAATTCCCCTCTTCTGGGGAAACACATGGAAA...
Task1_train_48627	A mutation located on Chromosome 22 is being studied. Determine whether it’s pathogenic or benign, and specify the linked disease.	Benign	GGTTGCACATGGGGCCTTTGCATAGCATGGAAACATTGTTTCTTCAGGTTTGATTCTTGTATTTGCAGCTAGGTCATCAAGAAATATTCTGTTCCCCTGGGTCTAGCCCTGTATTTCAGTGGACTTGATTGAAACATTGTTTTAATTTGGAAATAGAGGAACTGTTGCATTACCTGCATGACGATTTGGTCATTACTTACTTGACTTTCTCATTTCCTTTCCCAAATAAACCTGTGCTTCTCAGATTGTTTTGATGGTGATCATACCTTTGAGGACATAGGACTTGCAGCTGGCCGAAGCCAACGAGAGAAAAAACGTTC...	GGTTGCACATGGGGCCTTTGCATAGCATGGAAACATTGTTTCTTCAGGTTTGATTCTTGTATTTGCAGCTAGGTCATCAAGAAATATTCTGTTCCCCTGGGTCTAGCCCTGTATTTCAGTGGACTTGATTGAAACATTGTTTTAATTTGGAAATAGAGGAACTGTTGCATTACCTGCATGACGATTTGGTCATTACTTACTTGACTTTCTCATTTCCTTTCCCAAATAAACCTGTGCTTCTCAGATTGTTTTGATGGTGATCATACCTTTGAGGACATAGGACTTGCAGCTGGCCGAAGCCAACGAGAGAAAAAACGTTC...
Task1_train_48628	Given a variant located on Chromosome 22, assess whether it is benign or pathogenic. Indicate the associated disease if pathogenic.	Benign	AAACCCTGTCTCTATTAAAAATACAAAAAATTAGCCAGGCTGGTAGTGCACACCTGTAGTCCCGTTACTCGGGAGGGTGAGGCAGGAGAATTGCTTGAACTGGGAGATCGCGCCATTGCACTGCAGCCTGGACAACAGACAGAGACCCCGTCTCAAAAAAAAAAAAAAAAAAAAAAAAGACGCCAAAGTGCCATGATAAGGGAGTGTTTCTATAAACATGACAATACATCTTCTCTTAAGGAAATAGCATAGAGTCATCAAAAATAATAGTTATAACAACTGTATAGCAAGATGGAAAATACTTGTATAACATTACATTT...	AAACCCTGTCTCTATTAAAAATACAAAAAATTAGCCAGGCTGGTAGTGCACACCTGTAGTCCCGTTACTCGGGAGGGTGAGGCAGGAGAATTGCTTGAACTGGGAGATCGCGCCATTGCACTGCAGCCTGGACAACAGACAGAGACCCCGTCTCAAAAAAAAAAAAAAAAAAAAAAAAGACGCCAAAGTGCCATGATAAGGGAGTGTTTCTATAAACATGACAATACATCTTCTCTTAAGGAAATAGCATAGAGTCATCAAAAATAATAGTTATAACAACTGTATAGCAAGATGGAAAATACTTGTATAACATTACATTT...
Task1_train_48629	A mutation on Chromosome 22 has been found. Is it harmful or harmless? What disease, if any, does it cause?	Benign	TCCTGACCTCAGGTGACCCACCCGCCTCGGTGTCCCAAAGTGCTGAGATTACAGGCGTGAGCCACCGTGCCCGGCCTTGTATCCACATACATTTAGAAGAGAGCTGTTTGTGGATGAATGGAATAGTAAGCCATCAGCCTAGGCCTGCATAGGGGTAGTTTGAACTGTGCTCCTGCTAAAAACACACGGCCACCCCCACCCAGGGCTCCAGGCCAGAGTGGACCTTCTGTCTGTCTGTCTGTCTGCTGCCCACATTGTAATAGCCCAGTGGGTTCATTTTGCCCTCTGCCCAGATAGAGTTGATTTATCAAGACAGGGGA...	TCCTGACCTCAGGTGACCCACCCGCCTCGGTGTCCCAAAGTGCTGAGATTACAGGCGTGAGCCACCGTGCCCGGCCTTGTATCCACATACATTTAGAAGAGAGCTGTTTGTGGATGAATGGAATAGTAAGCCATCAGCCTAGGCCTGCATAGGGGTAGTTTGAACTGTGCTCCTGCTAAAAACACACGGCCACCCCCACCCAGGGCTCCAGGCCAGAGTGGACCTTCTGTCTGTCTGTCTGTCTGCTGCCCACATTGTAATAGCCCAGTGGGTTCATTTTGCCCTCTGCCCAGATAGAGTTGATTTATCAAGACAGGGGA...
Task1_train_48630	Given this context: Chromosome 22 — does this variant present pathogenic behavior, and if so, what disease does it relate to?	Benign	GGTAGTTTGAACTGTGCTCCTGCTAAAAACACACGGCCACCCCCACCCAGGGCTCCAGGCCAGAGTGGACCTTCTGTCTGTCTGTCTGTCTGCTGCCCACATTGTAATAGCCCAGTGGGTTCATTTTGCCCTCTGCCCAGATAGAGTTGATTTATCAAGACAGGGGAATTGCAATAAAGAGTTTAATTCATGCAGAGCCAGATGAATGGGAGACTGGAGTTTTATTATTACTCAAGTCGGTTTCTCCAAAAATTCGAGGACTGGGTTTTTTGTTTTGTTTTTTTGTTTTGTTTTTTTAGATGAACTCTTGCTCTGTCACC...	GGTAGTTTGAACTGTGCTCCTGCTAAAAACACACGGCCACCCCCACCCAGGGCTCCAGGCCAGAGTGGACCTTCTGTCTGTCTGTCTGTCTGCTGCCCACATTGTAATAGCCCAGTGGGTTCATTTTGCCCTCTGCCCAGATAGAGTTGATTTATCAAGACAGGGGAATTGCAATAAAGAGTTTAATTCATGCAGAGCCAGATGAATGGGAGACTGGAGTTTTATTATTACTCAAGTCGGTTTCTCCAAAAATTCGAGGACTGGGTTTTTTGTTTTGTTTTTTTGTTTTGTTTTTTTAGATGAACTCTTGCTCTGTCACC...
Task1_train_48631	Consider a variant on Chromosome 22. Determine its clinical classification and disease relevance.	Benign	TGTGTAAAAGCTATCCAGGGCATCAAGGATCTTCATGCCTACCAGATGGCCAAATCCAACTCTGGCTTCATGGCTATGGTCAAGAATTTTGTGGCCAAGAGACACATCCCTTTCTGGACGGCTAGAGGGGTGCAGAGAGCCTTTGAGGGCACAACTCTGGCCATGACCAATGGTGCCTGGGTGATGGGTGCTGCTGGGGCTGGCTTCTTACTTATGAAAGACATGAGCAGCTTCCTGCAGAGCTGGAAGCACCTGGAGGATGGGGCAAGGACGGAGACAGCAGAGGAACTGAGAGCACTTGCTAAGAAGCTGGAGCAGGA...	TGTGTAAAAGCTATCCAGGGCATCAAGGATCTTCATGCCTACCAGATGGCCAAATCCAACTCTGGCTTCATGGCTATGGTCAAGAATTTTGTGGCCAAGAGACACATCCCTTTCTGGACGGCTAGAGGGGTGCAGAGAGCCTTTGAGGGCACAACTCTGGCCATGACCAATGGTGCCTGGGTGATGGGTGCTGCTGGGGCTGGCTTCTTACTTATGAAAGACATGAGCAGCTTCCTGCAGAGCTGGAAGCACCTGGAGGATGGGGCAAGGACGGAGACAGCAGAGGAACTGAGAGCACTTGCTAAGAAGCTGGAGCAGGA...
Task1_train_48632	A variant on Chromosome 22 is under investigation. Evaluate whether it is clinically benign or pathogenic and name the disorder if relevant.	Benign	GCAAGCAGGAAGCTCAGGATTTGACTCAAGGCCAGCGTTCCCTTGCCATTACTTTGAAGACTCCATATATTTTGAAAATGCCTGTGGTTCCTGCATTCTCCACTGTAGTATACCTGTGGGATTTTAAACATTTTATTGAAAAAGAATATTTCAACCCTACACCATTGAATAAACTACCATGCACAGAGGATTCCTCCTGCTGCTCATGGGCGCTCTCAGATGGGCAGTGGAGGGGGTTCTTTAGGCGGGCAGGGGAGCAAGACCCTCAGCACTGATCCCTGTGGCCCTTCTGTGTTACCTCTGTCCTCTGCAGGCTGGTC...	GCAAGCAGGAAGCTCAGGATTTGACTCAAGGCCAGCGTTCCCTTGCCATTACTTTGAAGACTCCATATATTTTGAAAATGCCTGTGGTTCCTGCATTCTCCACTGTAGTATACCTGTGGGATTTTAAACATTTTATTGAAAAAGAATATTTCAACCCTACACCATTGAATAAACTACCATGCACAGAGGATTCCTCCTGCTGCTCATGGGCGCTCTCAGATGGGCAGTGGAGGGGGTTCTTTAGGCGGGCAGGGGAGCAAGACCCTCAGCACTGATCCCTGTGGCCCTTCTGTGTTACCTCTGTCCTCTGCAGGCTGGTC...
Task1_train_48633	A mutation found on Chromosome 22 may be clinically relevant. Is it pathogenic or benign, and if the former, which disease is implicated?	Benign	AGAATCACTTGAACCCAGGAGGCGGAGGGTGCAGTGAGCCGATGGTGCTACTTGCACTCCAGCCTGGGCGACAGAGCAAGACTCCGTCAGAAAAAAAAGACTAATGAATGCGATGCCTCCCTTAAAGAAATGAGGAGGAAAAGAAGCTGCACAGAATCAAAGACCCTTCGAGGCCACGACACAGAGGTGAGAAACACAGGGCTCCATGAAGTGAAATCTGAATAGCAGGTGTGAGTGTGCGTGTGTGTGTGTGTGTGTGTGTGTGAATTTGTGAGTGTGTGTGTGGCATATGCAAGGTTTGCCTTTTATTTGGTTGCCAG...	AGAATCACTTGAACCCAGGAGGCGGAGGGTGCAGTGAGCCGATGGTGCTACTTGCACTCCAGCCTGGGCGACAGAGCAAGACTCCGTCAGAAAAAAAAGACTAATGAATGCGATGCCTCCCTTAAAGAAATGAGGAGGAAAAGAAGCTGCACAGAATCAAAGACCCTTCGAGGCCACGACACAGAGGTGAGAAACACAGGGCTCCATGAAGTGAAATCTGAATAGCAGGTGTGAGTGTGCGTGTGTGTGTGTGTGTGTGTGTGTGAATTTGTGAGTGTGTGTGTGGCATATGCAAGGTTTGCCTTTTATTTGGTTGCCAG...
Task1_train_48634	This alteration on Chromosome 22 may affect genome function. Does it lead to a disease or is it benign?	Benign	GAATGACTTAAACAAGTCCAGCTTGGCGAGTAGCTAAGTTTATTAGGACTTACACACAGGGCACTCAGCAAGACAGCTCGAGAGATCCAGCCTCCCCCAATGTCTAAACTGCTTTTCAGTTAATTTTCTGGCTCTTTGTCTACTATATATGAGCAACGAGACTTTTACTTGGTTGGTTCTCAGATACTCTCCAGGATGTTTGGATTCTCAGAGACACCTGGTCCTCAGCTGGGCACCATGGAAATGGCTCATTACCCGGCCTTCAGGGTTCAAGCAGGGGACATGCACCCTTAAATAACCTAAAGGGGACCTGTCACACT...	GAATGACTTAAACAAGTCCAGCTTGGCGAGTAGCTAAGTTTATTAGGACTTACACACAGGGCACTCAGCAAGACAGCTCGAGAGATCCAGCCTCCCCCAATGTCTAAACTGCTTTTCAGTTAATTTTCTGGCTCTTTGTCTACTATATATGAGCAACGAGACTTTTACTTGGTTGGTTCTCAGATACTCTCCAGGATGTTTGGATTCTCAGAGACACCTGGTCCTCAGCTGGGCACCATGGAAATGGCTCATTACCCGGCCTTCAGGGTTCAAGCAGGGGACATGCACCCTTAAATAACCTAAAGGGGACCTGTCACACT...
Task1_train_48635	Here is a mutation located on Chromosome 22. Determine whether it’s benign or pathogenic. If the latter, what disease does it cause?	Benign	CTTGGCGAGTAGCTAAGTTTATTAGGACTTACACACAGGGCACTCAGCAAGACAGCTCGAGAGATCCAGCCTCCCCCAATGTCTAAACTGCTTTTCAGTTAATTTTCTGGCTCTTTGTCTACTATATATGAGCAACGAGACTTTTACTTGGTTGGTTCTCAGATACTCTCCAGGATGTTTGGATTCTCAGAGACACCTGGTCCTCAGCTGGGCACCATGGAAATGGCTCATTACCCGGCCTTCAGGGTTCAAGCAGGGGACATGCACCCTTAAATAACCTAAAGGGGACCTGTCACACTACAACCACCACCACCATCATC...	CTTGGCGAGTAGCTAAGTTTATTAGGACTTACACACAGGGCACTCAGCAAGACAGCTCGAGAGATCCAGCCTCCCCCAATGTCTAAACTGCTTTTCAGTTAATTTTCTGGCTCTTTGTCTACTATATATGAGCAACGAGACTTTTACTTGGTTGGTTCTCAGATACTCTCCAGGATGTTTGGATTCTCAGAGACACCTGGTCCTCAGCTGGGCACCATGGAAATGGCTCATTACCCGGCCTTCAGGGTTCAAGCAGGGGACATGCACCCTTAAATAACCTAAAGGGGACCTGTCACACTACAACCACCACCACCATCATC...
Task1_train_48636	Given this context: Chromosome 22 — does this variant present pathogenic behavior, and if so, what disease does it relate to?	Benign	CCTGTCACACTACAACCACCACCACCATCATCAAGAAGCCACTGGCTGACTCAGATACACCCCCGGGAGGACAAGGGAGAGTGGATGCTGGTAAGACAGGGTGAGAGACCATCACCAGGGAAGGATTCCATTCTTGGAAGGACATCCAACCGGGGGGCGGGTCTTTAGTGGAGCCGCTGTTTCTTCTCCTGTATCCAACAGTTCTAACTGTGGCTTTCTCCATTTTCAGCTCTTTCTTTTCCTGGTCTTCTCATTGCTTGTTCCTACGTGCCTCCCTCTCTTCCTCCCCCAATATACTCTTTAGTCTAGAGTAAACTGCT...	CCTGTCACACTACAACCACCACCACCATCATCAAGAAGCCACTGGCTGACTCAGATACACCCCCGGGAGGACAAGGGAGAGTGGATGCTGGTAAGACAGGGTGAGAGACCATCACCAGGGAAGGATTCCATTCTTGGAAGGACATCCAACCGGGGGGCGGGTCTTTAGTGGAGCCGCTGTTTCTTCTCCTGTATCCAACAGTTCTAACTGTGGCTTTCTCCATTTTCAGCTCTTTCTTTTCCTGGTCTTCTCATTGCTTGTTCCTACGTGCCTCCCTCTCTTCCTCCCCCAATATACTCTTTAGTCTAGAGTAAACTGCT...
Task1_train_48637	This variant is present on Chromosome 22. Is the change likely to result in a pathogenic outcome?	Benign	TCCAACAGTTCTAACTGTGGCTTTCTCCATTTTCAGCTCTTTCTTTTCCTGGTCTTCTCATTGCTTGTTCCTACGTGCCTCCCTCTCTTCCTCCCCCAATATACTCTTTAGTCTAGAGTAAACTGCTTCTTTCCATTCCCCACACTCTCCAGTCCCCTCTCCTCCCTTATTCCAGGCCCCAGCATTTCTGCCTTCTCCTTGGCGCACTTGCCATCTTGAGTAACCCCTCCCCTGCTGTGCTCAGCTACAGATGCCAAAGTTCCTAACACTGAGTTCCATAAACTTTACCTCGCCCTCTTTATTCCCCTAAAAAATGTCTG...	TCCAACAGTTCTAACTGTGGCTTTCTCCATTTTCAGCTCTTTCTTTTCCTGGTCTTCTCATTGCTTGTTCCTACGTGCCTCCCTCTCTTCCTCCCCCAATATACTCTTTAGTCTAGAGTAAACTGCTTCTTTCCATTCCCCACACTCTCCAGTCCCCTCTCCTCCCTTATTCCAGGCCCCAGCATTTCTGCCTTCTCCTTGGCGCACTTGCCATCTTGAGTAACCCCTCCCCTGCTGTGCTCAGCTACAGATGCCAAAGTTCCTAACACTGAGTTCCATAAACTTTACCTCGCCCTCTTTATTCCCCTAAAAAATGTCTG...
Task1_train_48638	A mutation on Chromosome 22 is under examination. Does this mutation cause a disorder, or is it a benign change?	Benign	CCGTCGCCACATTCGGCTAATTTTTTGTATTTTCAGTAGAGAAGGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCATGATCAGCCCGTCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCGGTCGCGCCGGGCCTGTGATGTGCAGGGCTTCTGACATGTGTCTCATTCAATGATCACACACAGCCCGGGAGATGGGTACCACTTTCCCATTTGAACACAGAGGAATCCACAAAAGTTAGGGAACTTGCCAGTGTTTTCTATTGCTAGAGCCAGGACTTCTGCTTCAACCTCATGTCTTCAA...	CCGTCGCCACATTCGGCTAATTTTTTGTATTTTCAGTAGAGAAGGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCATGATCAGCCCGTCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCGGTCGCGCCGGGCCTGTGATGTGCAGGGCTTCTGACATGTGTCTCATTCAATGATCACACACAGCCCGGGAGATGGGTACCACTTTCCCATTTGAACACAGAGGAATCCACAAAAGTTAGGGAACTTGCCAGTGTTTTCTATTGCTAGAGCCAGGACTTCTGCTTCAACCTCATGTCTTCAA...
Task1_train_48639	A mutation is present on Chromosome 22. Based on this information, is the variant pathogenic or benign? Provide the disease if relevant.	Benign	CATTCGGCTAATTTTTTGTATTTTCAGTAGAGAAGGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCATGATCAGCCCGTCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCGGTCGCGCCGGGCCTGTGATGTGCAGGGCTTCTGACATGTGTCTCATTCAATGATCACACACAGCCCGGGAGATGGGTACCACTTTCCCATTTGAACACAGAGGAATCCACAAAAGTTAGGGAACTTGCCAGTGTTTTCTATTGCTAGAGCCAGGACTTCTGCTTCAACCTCATGTCTTCAATGACTGTGC...	CATTCGGCTAATTTTTTGTATTTTCAGTAGAGAAGGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCATGATCAGCCCGTCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCGGTCGCGCCGGGCCTGTGATGTGCAGGGCTTCTGACATGTGTCTCATTCAATGATCACACACAGCCCGGGAGATGGGTACCACTTTCCCATTTGAACACAGAGGAATCCACAAAAGTTAGGGAACTTGCCAGTGTTTTCTATTGCTAGAGCCAGGACTTCTGCTTCAACCTCATGTCTTCAATGACTGTGC...