Split (2)

train · 48.9k rows

Subsets and Splits

No community queries yet

The top public SQL queries from the community will appear here once available.

ID stringlengths 13 17	question stringlengths 88 1.13k	answer stringlengths 6 156	reference_sequence stringlengths 4.1k 4.1k	variant_sequence stringlengths 4.1k 4.1k
Task1_train_48800	Chromosome 22 carries this variant. Does this mutation lead to a specific disease, or is it non-pathogenic?	Benign	GCTCCCTCAGTGCCCCCCTAGCAGCCCCGGCGGTCTTCTCCCCACCTTCAGCCCCCTCCCCGGTCCCCCAGGAAGGGGCCAGACTCCAGCTCAGCACCCAGCGCTTCCTGGTCTTTCCCTTCTGGGCGCCCTCCCGACAGTTCCCTTTAGGGAAGTTGGCCCGCTGCGCGCTCCCACCCCCGGCCGCCGCCTGGACAGAGGCGCGCAATCCGGAGGGCGCAGGCTCCGGCCCGGAGAAGGGGGTGCCGCCGGCGTTCCGATTTCTCAGGAATGGGGAAACAGAGGCACGGTGGATCCGGCGGCGGGGCTGGGTCTGGGGC...	GCTCCCTCAGTGCCCCCCTAGCAGCCCCGGCGGTCTTCTCCCCACCTTCAGCCCCCTCCCCGGTCCCCCAGGAAGGGGCCAGACTCCAGCTCAGCACCCAGCGCTTCCTGGTCTTTCCCTTCTGGGCGCCCTCCCGACAGTTCCCTTTAGGGAAGTTGGCCCGCTGCGCGCTCCCACCCCCGGCCGCCGCCTGGACAGAGGCGCGCAATCCGGAGGGCGCAGGCTCCGGCCCGGAGAAGGGGGTGCCGCCGGCGTTCCGATTTCTCAGGAATGGGGAAACAGAGGCACGGTGGATCCGGCGGCGGGGCTGGGTCTGGGGC...
Task1_train_48801	A mutation has occurred on Chromosome 22. What is the medical relevance of this mutation?	Benign	TCTGGGCGCCCTCCCGACAGTTCCCTTTAGGGAAGTTGGCCCGCTGCGCGCTCCCACCCCCGGCCGCCGCCTGGACAGAGGCGCGCAATCCGGAGGGCGCAGGCTCCGGCCCGGAGAAGGGGGTGCCGCCGGCGTTCCGATTTCTCAGGAATGGGGAAACAGAGGCACGGTGGATCCGGCGGCGGGGCTGGGTCTGGGGCTGGACGTTGACCTAGGACCCCGCCCCTGCCCGCCCTGCGCCGCGCCCCTCCCGGGCCGGCCTTGACCGAGCAGCTCCACGCGGGCCCGGGGCTCGTCCACCCGACAGGAGCGGGGGGCTG...	TCTGGGCGCCCTCCCGACAGTTCCCTTTAGGGAAGTTGGCCCGCTGCGCGCTCCCACCCCCGGCCGCCGCCTGGACAGAGGCGCGCAATCCGGAGGGCGCAGGCTCCGGCCCGGAGAAGGGGGTGCCGCCGGCGTTCCGATTTCTCAGGAATGGGGAAACAGAGGCACGGTGGATCCGGCGGCGGGGCTGGGTCTGGGGCTGGACGTTGACCTAGGACCCCGCCCCTGCCCGCCCTGCGCCGCGCCCCTCCCGGGCCGGCCTTGACCGAGCAGCTCCACGCGGGCCCGGGGCTCGTCCACCCGACAGGAGCGGGGGGCTG...
Task1_train_48802	A mutation located on Chromosome 22 is being studied. Determine whether it’s pathogenic or benign, and specify the linked disease.	Benign	GCCCGCTGCGCGCTCCCACCCCCGGCCGCCGCCTGGACAGAGGCGCGCAATCCGGAGGGCGCAGGCTCCGGCCCGGAGAAGGGGGTGCCGCCGGCGTTCCGATTTCTCAGGAATGGGGAAACAGAGGCACGGTGGATCCGGCGGCGGGGCTGGGTCTGGGGCTGGACGTTGACCTAGGACCCCGCCCCTGCCCGCCCTGCGCCGCGCCCCTCCCGGGCCGGCCTTGACCGAGCAGCTCCACGCGGGCCCGGGGCTCGTCCACCCGACAGGAGCGGGGGGCTGCAGCCCACGAGCCCACGAGCCCGCAGCGACGCACCCGG...	GCCCGCTGCGCGCTCCCACCCCCGGCCGCCGCCTGGACAGAGGCGCGCAATCCGGAGGGCGCAGGCTCCGGCCCGGAGAAGGGGGTGCCGCCGGCGTTCCGATTTCTCAGGAATGGGGAAACAGAGGCACGGTGGATCCGGCGGCGGGGCTGGGTCTGGGGCTGGACGTTGACCTAGGACCCCGCCCCTGCCCGCCCTGCGCCGCGCCCCTCCCGGGCCGGCCTTGACCGAGCAGCTCCACGCGGGCCCGGGGCTCGTCCACCCGACAGGAGCGGGGGGCTGCAGCCCACGAGCCCACGAGCCCGCAGCGACGCACCCGG...
Task1_train_48803	Chromosome 22 houses a mutation. Classify its clinical impact — is it pathogenic or benign, and what disease does it lead to if any?	Benign	TTTTCGTCTGGGTTGATGATTTCACACGTTAGCTAGAGTTTTTCAAATTCGTATTTCATGTATCAGGTCTTCTAGCAAGGAAGGATGAATAGATCTCAAGGAATTCAGCTTTGCTGATTATAGCAGCTGTGAGTACCTCTCATGAACTGTTTGAAGGATGAGGGCATAAATTCTAGATGAGGCAACCTCTTTATACCATTCTAGGTTTTAATTCATGTTCCCCAATCCTTTATTAATAGGCCACTTGCATTTTTTTTCATGTCTCTATTTTTTGCTTATTTTGCAATTTGGGGGTATTGTCATCCTGTAAACGGATTGCA...	TTTTCGTCTGGGTTGATGATTTCACACGTTAGCTAGAGTTTTTCAAATTCGTATTTCATGTATCAGGTCTTCTAGCAAGGAAGGATGAATAGATCTCAAGGAATTCAGCTTTGCTGATTATAGCAGCTGTGAGTACCTCTCATGAACTGTTTGAAGGATGAGGGCATAAATTCTAGATGAGGCAACCTCTTTATACCATTCTAGGTTTTAATTCATGTTCCCCAATCCTTTATTAATAGGCCACTTGCATTTTTTTTCATGTCTCTATTTTTTGCTTATTTTGCAATTTGGGGGTATTGTCATCCTGTAAACGGATTGCA...
Task1_train_48804	A variant was discovered on Chromosome 22. What is its functional impact — neutral or pathogenic? State the disease if pathogenic.	Benign	TGGTGTGTGCACATGTGCACTGTGTGGTGTGTATGCATGGTGTGTGCACGTGTGCACTGTGTATGCATGGTGTGTGCATGTGTGCACTGTATGCATAGTGTGCACGTGTGCACTGTGTGTGGATGCATGGTAATGTGCACGTGTGCACTGTGTGTGGTGTGTATGCATGGTGTGTGCACGTGTGCACGGTGTGTGGTGTGTATGCATGGTGTGTGCACATGTGCACTGTGTATGCATGGTGTGTGCACGTGTGCACTGTGTATGCATGGTGTGTGCACGTGTGCACTGTGTGGTGTGTATGCATGGTGTGTGCACATGTG...	TGGTGTGTGCACATGTGCACTGTGTGGTGTGTATGCATGGTGTGTGCACGTGTGCACTGTGTATGCATGGTGTGTGCATGTGTGCACTGTATGCATAGTGTGCACGTGTGCACTGTGTGTGGATGCATGGTAATGTGCACGTGTGCACTGTGTGTGGTGTGTATGCATGGTGTGTGCACGTGTGCACGGTGTGTGGTGTGTATGCATGGTGTGTGCACATGTGCACTGTGTATGCATGGTGTGTGCACGTGTGCACTGTGTATGCATGGTGTGTGCACGTGTGCACTGTGTGGTGTGTATGCATGGTGTGTGCACATGTG...
Task1_train_48805	A mutation has occurred on Chromosome 22. What is the medical relevance of this mutation?	Benign	GTGAGTGCCTTAAAACCTCTTAGAAGATACTTTTTATTTTCCAACTTAGAATTTGAAATAACCTCAGACTTAGAAAGGTACAGGAACAGTAGGGAGCTCCCACCTGCCTCGCACCCACCTTACCCCTGCATTACCGTTTTTTATCACCAGAGTCAGCGATCAAAACCAGGAAATTAAGGAGAAGATTCTGTCCACACCTAGACTCTTGTTTCCTGGACCTTACAATACTCCAGAGCATATGTTACGTTCAGCTGCATGTTTGTTTTAAAGAACCGTGTCTGCTGGGATTCAGTGAATGTTTTCCTCCATCCTCAGGAAGA...	GTGAGTGCCTTAAAACCTCTTAGAAGATACTTTTTATTTTCCAACTTAGAATTTGAAATAACCTCAGACTTAGAAAGGTACAGGAACAGTAGGGAGCTCCCACCTGCCTCGCACCCACCTTACCCCTGCATTACCGTTTTTTATCACCAGAGTCAGCGATCAAAACCAGGAAATTAAGGAGAAGATTCTGTCCACACCTAGACTCTTGTTTCCTGGACCTTACAATACTCCAGAGCATATGTTACGTTCAGCTGCATGTTTGTTTTAAAGAACCGTGTCTGCTGGGATTCAGTGAATGTTTTCCTCCATCCTCAGGAAGA...
Task1_train_48806	This variant lies on Chromosome 22. Based on this context, is the mutation pathogenic or benign? If pathogenic, what disease does it cause?	Benign	TCATTTATGGCTTCTTAGTGTCACTTCCATACATCCTGCCTGCCCTGAGAACACTTAGTGTGGCAAAGTAAGTCATAGGTATTTGCTGCAGGAAAATCAGAAAATTCAAGTCAGATGAAAAGAAAACAGTTAAAAACCCAGGAACTCCCTGGAGAGCGCACCCTGCTGGTGCCTCCACTGCTCGTGCCCCCCCAGCGCCCCCGCAACGTGCCCTGCGTGACTTTCCGCAGCGCCTGTCGGGTGTTTTCCACTCAGCAGCTTGTTGCGAACGTCTCTGCGTCCTGTGGTTTCTCTGTCACGCTAATGATTTTGGAGCCATT...	TCATTTATGGCTTCTTAGTGTCACTTCCATACATCCTGCCTGCCCTGAGAACACTTAGTGTGGCAAAGTAAGTCATAGGTATTTGCTGCAGGAAAATCAGAAAATTCAAGTCAGATGAAAAGAAAACAGTTAAAAACCCAGGAACTCCCTGGAGAGCGCACCCTGCTGGTGCCTCCACTGCTCGTGCCCCCCCAGCGCCCCCGCAACGTGCCCTGCGTGACTTTCCGCAGCGCCTGTCGGGTGTTTTCCACTCAGCAGCTTGTTGCGAACGTCTCTGCGTCCTGTGGTTTCTCTGTCACGCTAATGATTTTGGAGCCATT...
Task1_train_48807	This mutation is located on Chromosome 22. Is it associated with a disease or is it a benign polymorphism?	Benign	GAAAATCAGAAAATTCAAGTCAGATGAAAAGAAAACAGTTAAAAACCCAGGAACTCCCTGGAGAGCGCACCCTGCTGGTGCCTCCACTGCTCGTGCCCCCCCAGCGCCCCCGCAACGTGCCCTGCGTGACTTTCCGCAGCGCCTGTCGGGTGTTTTCCACTCAGCAGCTTGTTGCGAACGTCTCTGCGTCCTGTGGTTTCTCTGTCACGCTAATGATTTTGGAGCCATTATTTCATACTTTTACAACAATGTCTGTTGCTGGACGTTTACGTCATAACAGTTTTTCAACTTATAAACTGTGAACACTTGAAGGTAAACTT...	GAAAATCAGAAAATTCAAGTCAGATGAAAAGAAAACAGTTAAAAACCCAGGAACTCCCTGGAGAGCGCACCCTGCTGGTGCCTCCACTGCTCGTGCCCCCCCAGCGCCCCCGCAACGTGCCCTGCGTGACTTTCCGCAGCGCCTGTCGGGTGTTTTCCACTCAGCAGCTTGTTGCGAACGTCTCTGCGTCCTGTGGTTTCTCTGTCACGCTAATGATTTTGGAGCCATTATTTCATACTTTTACAACAATGTCTGTTGCTGGACGTTTACGTCATAACAGTTTTTCAACTTATAAACTGTGAACACTTGAAGGTAAACTT...
Task1_train_48808	This alteration occurs on Chromosome 22. Is it associated with a disease or is it a benign variant?	Benign	GCGTGGACCACCTCCCGGTGAAGATCCTGCAGCCAGGTACGCGCGGGGCCGGCGGGGCCGGGGCCGGGGCCAGGGCGGGGACCGGGGGCGCCCCGGGCCGCACCAACCCCGCCCGCGCCTCCCTGCAGCCAAGGCGGACAAGGAGAGCTTCGAGAAGGCGTACCAGGTGGGCGCCGTGCTGGGTAGCGGCGGCTTCGGCACGGTCTACGCGGGTAGCCGCATCGCCGACGGGCTCCCGGTGAGTCGGACCGCCGGGCGGGCCCGGGTTTCTCGCGCGCCTTGCGCCTCGCTTGGCCCGGCCTGACCCCCGCGTCTCCGCA...	GCGTGGACCACCTCCCGGTGAAGATCCTGCAGCCAGGTACGCGCGGGGCCGGCGGGGCCGGGGCCGGGGCCAGGGCGGGGACCGGGGGCGCCCCGGGCCGCACCAACCCCGCCCGCGCCTCCCTGCAGCCAAGGCGGACAAGGAGAGCTTCGAGAAGGCGTACCAGGTGGGCGCCGTGCTGGGTAGCGGCGGCTTCGGCACGGTCTACGCGGGTAGCCGCATCGCCGACGGGCTCCCGGTGAGTCGGACCGCCGGGCGGGCCCGGGTTTCTCGCGCGCCTTGCGCCTCGCTTGGCCCGGCCTGACCCCCGCGTCTCCGCA...
Task1_train_48809	This is a variant located on Chromosome 22. Is this mutation a likely cause of disease or not?	Benign	GGATCTGGGGAAGCTGAGACCCTCTGGAGGGGTCCGAGTGGGGCGGGTGCCCCAGTGAAGCTCAGCACCCAAGGATGCACAGACAGGAGAGGTGGACTCCAGCCAGTGTGGGGTGCCCTGGGCAGAAACTGGGGTGATCCTTGACCACCTCGGGCCTGATCAGCTACAGGAAGGGTGGGGTTGCACCCTGCACCCCAGAGCACTGGGGAAGCTCCAGGCAGCTGCCAGGGCCTTGTCTTCAGGGCCAGGGACAGTGGCCATGACCATGAATTGTCTGAGAGGGAGGCTGGGGTCCAGCACCTGGGCCATCCGGGGAAGGG...	GGATCTGGGGAAGCTGAGACCCTCTGGAGGGGTCCGAGTGGGGCGGGTGCCCCAGTGAAGCTCAGCACCCAAGGATGCACAGACAGGAGAGGTGGACTCCAGCCAGTGTGGGGTGCCCTGGGCAGAAACTGGGGTGATCCTTGACCACCTCGGGCCTGATCAGCTACAGGAAGGGTGGGGTTGCACCCTGCACCCCAGAGCACTGGGGAAGCTCCAGGCAGCTGCCAGGGCCTTGTCTTCAGGGCCAGGGACAGTGGCCATGACCATGAATTGTCTGAGAGGGAGGCTGGGGTCCAGCACCTGGGCCATCCGGGGAAGGG...
Task1_train_48810	Chromosome 22 houses a mutation. Classify its clinical impact — is it pathogenic or benign, and what disease does it lead to if any?	Benign	GGATTGCTGCAGGAGGAACTTCGCCTCCCGTGGGGCAAGAGGCATCTCCGTGAGTGGGTCCCAGCCCCTGAATCGCAGTGGGAATCAGGGAGGCGGCAACACCTGCGTGCCGTCATAAAGACCCCCACCATGCCCTCGTAAAGACCCCCATCACACCGTCCTGAAGACCCCCACATACCCTCGTAAAGACCCCATCACACCATCCTAAAGACCCCCACACACACTCGTAAAGACCCCATCACACCATCCTGAAGACCCCACACACCCTCGTAAAGACCCCATCACACCGTCCTAAAGACCCCCACATACCCTCGTAAAGA...	GGATTGCTGCAGGAGGAACTTCGCCTCCCGTGGGGCAAGAGGCATCTCCGTGAGTGGGTCCCAGCCCCTGAATCGCAGTGGGAATCAGGGAGGCGGCAACACCTGCGTGCCGTCATAAAGACCCCCACCATGCCCTCGTAAAGACCCCCATCACACCGTCCTGAAGACCCCCACATACCCTCGTAAAGACCCCATCACACCATCCTAAAGACCCCCACACACACTCGTAAAGACCCCATCACACCATCCTGAAGACCCCACACACCCTCGTAAAGACCCCATCACACCGTCCTAAAGACCCCCACATACCCTCGTAAAGA...
Task1_train_48811	A genomic variant on Chromosome 22 is under review. What is the biological outcome — benign or pathogenic?	Benign	CCCGCGGTCACTTTGGCCCCTCGCTCGGCCAGGGAGCTTGGTGCTGTTCACGGCGCTGTTCAAGGTCCTAACTCAAATCCTCCGACCCGCGCCACACCCCAGAGGTATGGGGACAAAGGCGTCACCCGCCAGGTTCTACAGAGGGGACCCCACCATCCACCTGGCCGGCACTCCCACGCCCCCCACCCCGAGACCCCCGTGCCGGGCTGGGACAGGTGCCCCAACCCCGCTCCCCGGCTCCCGCCGGCGCCTCCGTCAGGGGACACCCCGGGCCCCAGCACCGAAGCCTGCCCTGCGCCCCGCTCTGGAGGATGCAGCGG...	CCCGCGGTCACTTTGGCCCCTCGCTCGGCCAGGGAGCTTGGTGCTGTTCACGGCGCTGTTCAAGGTCCTAACTCAAATCCTCCGACCCGCGCCACACCCCAGAGGTATGGGGACAAAGGCGTCACCCGCCAGGTTCTACAGAGGGGACCCCACCATCCACCTGGCCGGCACTCCCACGCCCCCCACCCCGAGACCCCCGTGCCGGGCTGGGACAGGTGCCCCAACCCCGCTCCCCGGCTCCCGCCGGCGCCTCCGTCAGGGGACACCCCGGGCCCCAGCACCGAAGCCTGCCCTGCGCCCCGCTCTGGAGGATGCAGCGG...
Task1_train_48812	This alteration on Chromosome 22 may affect genome function. Does it lead to a disease or is it benign?	Benign	TACAGATGTGCCAGCGTGGATGGACCTCACCAACCCCACGTGTGCCAGCGTGGATGGACCTCACGGATCTCATGTGTGTCAGTGTGGACAGACCTCACTGACCCCACGTGTATCAGTGTGGACGGACCTCATGGACCTCATGTGTGCCAGTGTGGATGGATCTCACAGACCTCACATGTATCAGCGTGGACAGACCTCACAGACCTCACATGTGCCAGCGTGGATGGACCTCATGGACCTCATGTGTGTCGGTGTGGACAGACCTCACTGACCCCACGTGTATCAGTGTGGACGGACCTCACGGACCTCATGTGTGCCAG...	TACAGATGTGCCAGCGTGGATGGACCTCACCAACCCCACGTGTGCCAGCGTGGATGGACCTCACGGATCTCATGTGTGTCAGTGTGGACAGACCTCACTGACCCCACGTGTATCAGTGTGGACGGACCTCATGGACCTCATGTGTGCCAGTGTGGATGGATCTCACAGACCTCACATGTATCAGCGTGGACAGACCTCACAGACCTCACATGTGCCAGCGTGGATGGACCTCATGGACCTCATGTGTGTCGGTGTGGACAGACCTCACTGACCCCACGTGTATCAGTGTGGACGGACCTCACGGACCTCATGTGTGCCAG...
Task1_train_48813	A mutation on Chromosome 22 is under examination. Does this mutation cause a disorder, or is it a benign change?	Benign	GGGCAGCCAGGCCTTGCGTCCAGAAGGCACAAAACTCCAGATGCACAAATAAAGCTGAATTCCCAGCCAGGCACGGCGGCTCATGCCTGTAATCCTAGCACTTTGGGAGGCCGAGGCAGACGGATCGTGAGGTCAGGAGTTTGAGTACAGCCTGGCCAACATGGTAAACCCCGTCTCTACTAAAAATAACAAAAATTAGCTGGGCGTGGTGGCGGGCACCTGTAATCCCAGCTACTCGGGAGGCTGAGGCGGGAGAATCGCTTCAACTCAGGAGGCAGAGGTTGCAGTGAACCAAGATCACACCACTGCACTCTAGCCTG...	GGGCAGCCAGGCCTTGCGTCCAGAAGGCACAAAACTCCAGATGCACAAATAAAGCTGAATTCCCAGCCAGGCACGGCGGCTCATGCCTGTAATCCTAGCACTTTGGGAGGCCGAGGCAGACGGATCGTGAGGTCAGGAGTTTGAGTACAGCCTGGCCAACATGGTAAACCCCGTCTCTACTAAAAATAACAAAAATTAGCTGGGCGTGGTGGCGGGCACCTGTAATCCCAGCTACTCGGGAGGCTGAGGCGGGAGAATCGCTTCAACTCAGGAGGCAGAGGTTGCAGTGAACCAAGATCACACCACTGCACTCTAGCCTG...
Task1_train_48814	This genomic variant is located on Chromosome 22. Can you determine its pathogenicity and name any linked disease?	Benign	CCCTGCTGGCTCCTGTATGTGTTCCAGCACCCAGCCCAAGACACAGGCTTAGCGGGGATTTGAAATGCTAGGGAGTGCGCCACTCTCTCCCTTCCCACAGCAAGAACTATCAGTACACTCTGCATCCATGGACAGGCAAGGTCCAGGCTGTCATCAGACTGACAGATCTGACCTAGGAAAATAAAGCTATGTCAATCAAAAATAAGTCGGGGCTGGGCGCAGTGGCTCACACCTGTAATCCCAGCACTCGGGAGGCCAAGGCGGGTGGATCACCTGCGGGTCAGAAGTTCGAGACCAGCCTGACCAACATGGTAAAACCT...	CCCTGCTGGCTCCTGTATGTGTTCCAGCACCCAGCCCAAGACACAGGCTTAGCGGGGATTTGAAATGCTAGGGAGTGCGCCACTCTCTCCCTTCCCACAGCAAGAACTATCAGTACACTCTGCATCCATGGACAGGCAAGGTCCAGGCTGTCATCAGACTGACAGATCTGACCTAGGAAAATAAAGCTATGTCAATCAAAAATAAGTCGGGGCTGGGCGCAGTGGCTCACACCTGTAATCCCAGCACTCGGGAGGCCAAGGCGGGTGGATCACCTGCGGGTCAGAAGTTCGAGACCAGCCTGACCAACATGGTAAAACCT...
Task1_train_48815	A mutation found on Chromosome 22 may be clinically relevant. Is it pathogenic or benign, and if the former, which disease is implicated?	Benign	GAGCGGCGCGGGCGCGTGCGGGCGGCGGCAGCGGCGGTGACGGCAGCCTAGGCCGGGCGAGGGCCATGCTGAGCCTCGCAGCCAAGCTGGTGGCCTTCTTCTGGAGGACGGCGGACACCCCTAGGGAGGAAGCCGGGCAGCTGGAGCCCGAGCTCGCGGAAGGTGGCTCGCGGGAGGCGGCTGGGAGGCGGGTCCCGGGCCCTCGCGTGTCGGCCACGAGGGAGCCGCGCCCATAGGTCTTTGAGTGCAGTGCGGGCCGGCAGGCAACGCTGGGCCCGGCCTTTCCTCATCTCCGCTGGCGGGGATCCCCGTTCGCCTCA...	GAGCGGCGCGGGCGCGTGCGGGCGGCGGCAGCGGCGGTGACGGCAGCCTAGGCCGGGCGAGGGCCATGCTGAGCCTCGCAGCCAAGCTGGTGGCCTTCTTCTGGAGGACGGCGGACACCCCTAGGGAGGAAGCCGGGCAGCTGGAGCCCGAGCTCGCGGAAGGTGGCTCGCGGGAGGCGGCTGGGAGGCGGGTCCCGGGCCCTCGCGTGTCGGCCACGAGGGAGCCGCGCCCATAGGTCTTTGAGTGCAGTGCGGGCCGGCAGGCAACGCTGGGCCCGGCCTTTCCTCATCTCCGCTGGCGGGGATCCCCGTTCGCCTCA...
Task1_train_48816	A genomic variant on Chromosome 22 is under review. What is the biological outcome — benign or pathogenic?	Benign	GCTCTGTCACCCAGGCTGGAGTGCAGTGGCACAATTGTAGCTCACTGCAGCCTGGAATTCCTGGGCTTAAGTCATCCCACCTTAGCCTCGTGAGTAGCTGGGACTTCAGGCTCATGCCACCACACCCCAACTAATTCTTTTTTTTTTTTTTTTTTTTTTTAGAGATGGGATCTTACTGTGTTGCCCAGGCTGGTCTCAAACTCCTGGGCTCAAGTGATCTTCCCACCTCAGCCTCACAAAGTGCTAGAAATCTTTACTATGATTCCATGATTCTGCTGGAAAAAAAAATTAATTGAATTTAACTTTTTTTTTCTTTAAAG...	GCTCTGTCACCCAGGCTGGAGTGCAGTGGCACAATTGTAGCTCACTGCAGCCTGGAATTCCTGGGCTTAAGTCATCCCACCTTAGCCTCGTGAGTAGCTGGGACTTCAGGCTCATGCCACCACACCCCAACTAATTCTTTTTTTTTTTTTTTTTTTTTTTAGAGATGGGATCTTACTGTGTTGCCCAGGCTGGTCTCAAACTCCTGGGCTCAAGTGATCTTCCCACCTCAGCCTCACAAAGTGCTAGAAATCTTTACTATGATTCCATGATTCTGCTGGAAAAAAAAATTAATTGAATTTAACTTTTTTTTTCTTTAAAG...
Task1_train_48817	Here’s a variant located on Chromosome 22. What is the predicted biological effect — harmless or disease-causing?	Benign	GGGGGAAAAACCTTCATTGTGGTCATCTGTGACGGAAAGTAAGGGCCTGGAGGTCTGGGGAGAGCCGCGTTTTTAAGTTTCTCTGATACTTCTAGGTTGGGTGTTATAAAAGGTACTCCTTTGTGGCGGGTGGATCACCTGAGACCAGGAGTTCGAAACCAGCCTGGCCACCATGGCGAAACCCCGCCTCTACTAAAAATACAAAAATTACTTGGGCCCCTGTAGTCCTAGCTACTCAGGAGGCTGAGGCAGTAGAATCGCTTAAATCCAGGTGACGGAGGGTGCAGTGAGCCAAGATCGCACGACTGCACTCCAGCCTG...	GGGGGAAAAACCTTCATTGTGGTCATCTGTGACGGAAAGTAAGGGCCTGGAGGTCTGGGGAGAGCCGCGTTTTTAAGTTTCTCTGATACTTCTAGGTTGGGTGTTATAAAAGGTACTCCTTTGTGGCGGGTGGATCACCTGAGACCAGGAGTTCGAAACCAGCCTGGCCACCATGGCGAAACCCCGCCTCTACTAAAAATACAAAAATTACTTGGGCCCCTGTAGTCCTAGCTACTCAGGAGGCTGAGGCAGTAGAATCGCTTAAATCCAGGTGACGGAGGGTGCAGTGAGCCAAGATCGCACGACTGCACTCCAGCCTG...
Task1_train_48818	With a mutation on Chromosome 22, classify this variant as benign or pathogenic. Include the disease if it's pathogenic.	Benign	GGCGGCTGTCTTTTCCCTGTGTCCTCACGCAGCAGAAGGGATGGGAGAGCTCTCTGTGCTCCCTTGTGTAAGGGCACTAATTCCATTCATGAGGCCCCACCCTCATGACCTAATCACTTGCCAAAGGCCTCAACTCCTCATACCCAGTAACATCACATTGGGGATGAAGTTTCACCATACGAAGCTGGGGGGAACACAAACCTAGTGTATGATATGTGCCTTTATGATAAGTCTCAAAATCAGGTAGTATCAAGCCTCCAACTTTGTTCCTTTTCAAGGTTGTCTGGCTGTTCCAGGTCTTTCTTCTTACATGGATTTTA...	GGCGGCTGTCTTTTCCCTGTGTCCTCACGCAGCAGAAGGGATGGGAGAGCTCTCTGTGCTCCCTTGTGTAAGGGCACTAATTCCATTCATGAGGCCCCACCCTCATGACCTAATCACTTGCCAAAGGCCTCAACTCCTCATACCCAGTAACATCACATTGGGGATGAAGTTTCACCATACGAAGCTGGGGGGAACACAAACCTAGTGTATGATATGTGCCTTTATGATAAGTCTCAAAATCAGGTAGTATCAAGCCTCCAACTTTGTTCCTTTTCAAGGTTGTCTGGCTGTTCCAGGTCTTTCTTCTTACATGGATTTTA...
Task1_train_48819	A mutation found on Chromosome 22 may be clinically relevant. Is it pathogenic or benign, and if the former, which disease is implicated?	Benign	GCCGGTGCTGGCACCCTTTACTGCAGAGATGAGCGATTGGGGTATGTGCTCATGAGGGGCAAGGAGAAGAGCAACTCTGAGACTGTCGCCTGGAAAACGGGGACTTTGAGGAGTGGGCTCTCATGCAGAAGGAAGAACAGTAGGGGGCGTGTGGCCTGTGACAGGCGGCTGCCGTCTCCACCCTGACTGGAGACTTGGTGTTTTAGCTTAGATACTTTAAGAAGACTTTTAGATTCTGGGTTGTTTTTTTCCAGGTACTCTGCAGATGTGGACATTTTTTAATCCAGTCTCTAATATTTGAGTGTGATCTCTAAAGCCGC...	GCCGGTGCTGGCACCCTTTACTGCAGAGATGAGCGATTGGGGTATGTGCTCATGAGGGGCAAGGAGAAGAGCAACTCTGAGACTGTCGCCTGGAAAACGGGGACTTTGAGGAGTGGGCTCTCATGCAGAAGGAAGAACAGTAGGGGGCGTGTGGCCTGTGACAGGCGGCTGCCGTCTCCACCCTGACTGGAGACTTGGTGTTTTAGCTTAGATACTTTAAGAAGACTTTTAGATTCTGGGTTGTTTTTTTCCAGGTACTCTGCAGATGTGGACATTTTTTAATCCAGTCTCTAATATTTGAGTGTGATCTCTAAAGCCGC...
Task1_train_48820	This alteration on Chromosome 22 may affect genome function. Does it lead to a disease or is it benign?	Benign	GACAGAGCTGGCTGGGGCCCAGGTGGCTGCTCCGCTCCCAGGGACAGATTCAGTCAGGGCTTCAGGGCATCTCTGCGATGCTGGGGCCGGTTGGTCACAGAGTAGAGAGTGGCGAGGCTGACACAGGTGTGGGGGCAGACAGTGGTCTCTGCTGTGGGTGGGCTTCAGAGAAAGCCTCTGGGTTTCTAGGGAGAATGGGCTCCCAGAGGTCAAGCTTTCCCACACCATCTTCCAAAGGGAAGGGCTGCCCTGTCTGAAGAGTCCCGCCCACGTGCAGGATGAGACGTGGAAAATATTGTTGCTTTAACTTAAAAAACAAG...	GACAGAGCTGGCTGGGGCCCAGGTGGCTGCTCCGCTCCCAGGGACAGATTCAGTCAGGGCTTCAGGGCATCTCTGCGATGCTGGGGCCGGTTGGTCACAGAGTAGAGAGTGGCGAGGCTGACACAGGTGTGGGGGCAGACAGTGGTCTCTGCTGTGGGTGGGCTTCAGAGAAAGCCTCTGGGTTTCTAGGGAGAATGGGCTCCCAGAGGTCAAGCTTTCCCACACCATCTTCCAAAGGGAAGGGCTGCCCTGTCTGAAGAGTCCCGCCCACGTGCAGGATGAGACGTGGAAAATATTGTTGCTTTAACTTAAAAAACAAG...
Task1_train_48821	A change on Chromosome 22 is being evaluated. Identify whether the variant is neutral or disease-linked. Mention the disease if applicable.	Benign	AAGGTGTTGTAGGACTGCTGCATGAGTGCAAAGTTGGGGTGCTCTGCACCCCGCGGGCCCCCAGGGGGCCCCCAGGCCTGGGAGATGAGCTGGCTGCGGAACTTGAGCACGAGGCTGAAGATGCTGTGGATGACGTTCATGACGGGCGCCGCCTTCTCCGTGAGCAGGCCCCTGGGGGGAAGCAGTGCTGCTGGGTGGGCTGAGCCGTGACCACAGGGACGCAGCCGCTGCCCAGGCCTCACCTGAAGACGGCCTTGTGCAGGTACTCTGCGTGCGCACGCTGGATCTCCTCCAGGTCGCCCACGGTGGCCAACCTGGCC...	AAGGTGTTGTAGGACTGCTGCATGAGTGCAAAGTTGGGGTGCTCTGCACCCCGCGGGCCCCCAGGGGGCCCCCAGGCCTGGGAGATGAGCTGGCTGCGGAACTTGAGCACGAGGCTGAAGATGCTGTGGATGACGTTCATGACGGGCGCCGCCTTCTCCGTGAGCAGGCCCCTGGGGGGAAGCAGTGCTGCTGGGTGGGCTGAGCCGTGACCACAGGGACGCAGCCGCTGCCCAGGCCTCACCTGAAGACGGCCTTGTGCAGGTACTCTGCGTGCGCACGCTGGATCTCCTCCAGGTCGCCCACGGTGGCCAACCTGGCC...
Task1_train_48822	With a mutation on Chromosome 22, classify this variant as benign or pathogenic. Include the disease if it's pathogenic.	Benign	CGCACGCTGGATCTCCTCCAGGTCGCCCACGGTGGCCAACCTGGCCCTGAACTCGCACCAGGTGACGTGCAGGATCTGGTTGGCGATGTAGCCCTGGATGACCTTCACGAAATGCTGCATCTCGTGCTTGAACAGCTGCAGCTGACGGAACTGCACAGAGCCGGCCATGTGGCTCAGCAGGGCTGGCGGAGGGCAGAAGGCAGAGGGCAGAGGTGAGCGCAGCCTCCAGCCAGGGGTGCGGGGCGCCGGGCTCCAGCGGGGCCTCACCTGTGCGCTTGAGGTGGAAGCAGACGTCCTTGAGCGCCCACATCATGAGCTTC...	CGCACGCTGGATCTCCTCCAGGTCGCCCACGGTGGCCAACCTGGCCCTGAACTCGCACCAGGTGACGTGCAGGATCTGGTTGGCGATGTAGCCCTGGATGACCTTCACGAAATGCTGCATCTCGTGCTTGAACAGCTGCAGCTGACGGAACTGCACAGAGCCGGCCATGTGGCTCAGCAGGGCTGGCGGAGGGCAGAAGGCAGAGGGCAGAGGTGAGCGCAGCCTCCAGCCAGGGGTGCGGGGCGCCGGGCTCCAGCGGGGCCTCACCTGTGCGCTTGAGGTGGAAGCAGACGTCCTTGAGCGCCCACATCATGAGCTTC...
Task1_train_48823	Consider this mutation on Chromosome 22. Is this a benign change or a disease-causing variant?	Benign	CCCTACCTCGCCTTCCTCTCCAGCTCCTCCTCCAGGGACTTCAGCCTTCTCTCCCTGTCTCGGAGTTCACGGGCGTAGCTGAAGTCATCATCCAGCTCCTCCTGCCTGGCCGCCTGGCGTCGCTATAAAACACATAGAGCCTGGCCTGTGAAATCAGAACTGACAGGCGTGACCCCGCAGGGACAGGTCCTACCCACCTCCTGGTCCTTCACAAATTGTTCTTTCAGCCTCTGAAACTGCTCACGCTTCCGGGCATCCAAGGCCATCCGTTCTGACATCTGCCGGTCTACATTGGGACAGTAAGGGGCGCACTGTCACAA...	CCCTACCTCGCCTTCCTCTCCAGCTCCTCCTCCAGGGACTTCAGCCTTCTCTCCCTGTCTCGGAGTTCACGGGCGTAGCTGAAGTCATCATCCAGCTCCTCCTGCCTGGCCGCCTGGCGTCGCTATAAAACACATAGAGCCTGGCCTGTGAAATCAGAACTGACAGGCGTGACCCCGCAGGGACAGGTCCTACCCACCTCCTGGTCCTTCACAAATTGTTCTTTCAGCCTCTGAAACTGCTCACGCTTCCGGGCATCCAAGGCCATCCGTTCTGACATCTGCCGGTCTACATTGGGACAGTAAGGGGCGCACTGTCACAA...
Task1_train_48824	A mutation on Chromosome 22 has been found. Is it harmful or harmless? What disease, if any, does it cause?	Benign	TGTGGGAAGAATTGGGGAGGTGGGTTCTAGGGGACTCCCAAGGAGCGGACAGGCCACCCACGGTCCAGGAGACCCCGGGGGGTTGGACTTGAAGCTCCCAAGCTGGGGCCTCCTGACAACCTTCAAGGACTTGAGGCCACGCCCTCGGACCCCAAACTGCCCCGAGCTCCTCCCTCTGGCCAGTGCACCAAGCCCAGCAGCCCTCGGGACGGAGCAGGTGCCCTGGGTACGGCATGTTGTGTACCACTGCCTCTTGGGCTCACCCACCCACCAGCTCCTCAGCCACTGCCCAGAGCCTGGGACCTTGGCCCCCTGCCCAG...	TGTGGGAAGAATTGGGGAGGTGGGTTCTAGGGGACTCCCAAGGAGCGGACAGGCCACCCACGGTCCAGGAGACCCCGGGGGGTTGGACTTGAAGCTCCCAAGCTGGGGCCTCCTGACAACCTTCAAGGACTTGAGGCCACGCCCTCGGACCCCAAACTGCCCCGAGCTCCTCCCTCTGGCCAGTGCACCAAGCCCAGCAGCCCTCGGGACGGAGCAGGTGCCCTGGGTACGGCATGTTGTGTACCACTGCCTCTTGGGCTCACCCACCCACCAGCTCCTCAGCCACTGCCCAGAGCCTGGGACCTTGGCCCCCTGCCCAG...
Task1_train_48825	With a mutation on Chromosome 22, classify this variant as benign or pathogenic. Include the disease if it's pathogenic.	Benign	GCGCGTTCCAGGGGAGGGTGGGGGCCTCAGCCACAGCCACTCGGCCTCCTCCCCTGAGGGGCTCTCAGGTACCTCAGGTACCTATGTCCCAAGGCAGCACTGGAGATTGTAGGTCAGAGGTCAGTGACCTTGTTCTCCAGTGCAGCGGCAATCTGCTGCAGGCGGAAGGCCAGCTGCATCTTCTGGGCGGCAGGATCCTCCTCCAAGGCATTGATGATCTGAGGGAGGGTCGCATCAGAGCACACCGGGGGACCGCCCAGCACCCCACCTGCCCCCGCCCCCGGGGGCCTGACCCTACCTCGTCATAGTACTTCTGCGTG...	GCGCGTTCCAGGGGAGGGTGGGGGCCTCAGCCACAGCCACTCGGCCTCCTCCCCTGAGGGGCTCTCAGGTACCTCAGGTACCTATGTCCCAAGGCAGCACTGGAGATTGTAGGTCAGAGGTCAGTGACCTTGTTCTCCAGTGCAGCGGCAATCTGCTGCAGGCGGAAGGCCAGCTGCATCTTCTGGGCGGCAGGATCCTCCTCCAAGGCATTGATGATCTGAGGGAGGGTCGCATCAGAGCACACCGGGGGACCGCCCAGCACCCCACCTGCCCCCGCCCCCGGGGGCCTGACCCTACCTCGTCATAGTACTTCTGCGTG...
Task1_train_48826	Assess the clinical impact of this variant found on Chromosome 22. State whether it’s pathogenic or benign, and the disease if applicable.	Benign	TCCGTCAGCGTCTTCATGGTGCAGCGCTCGGCACCCACGAAGGCCTCGGCCTCCTGCAGCGTCATCGCCTTGTTCAGATTGGTGCCCTGGGGAGGCGGCAGTGGTCGGGGTGAGGAGGAGGGAACCAGGGACAGGTGGACCAGCTCTCAGCCCAGACCCGAGCAGGACCCAGACACCCGGGGCTGCACCGTCCTCACCCGGGCGTGGATGAGCTTGTTGACCTGCTTCTTGACGCCACCTGTGAAGTTCTCAAAGGTGGGGTCAGGCACGTACTCGAAGGCCCCGGCCTCTGTTCTGAGCAGGGCACGGTGCCCGTCCAT...	TCCGTCAGCGTCTTCATGGTGCAGCGCTCGGCACCCACGAAGGCCTCGGCCTCCTGCAGCGTCATCGCCTTGTTCAGATTGGTGCCCTGGGGAGGCGGCAGTGGTCGGGGTGAGGAGGAGGGAACCAGGGACAGGTGGACCAGCTCTCAGCCCAGACCCGAGCAGGACCCAGACACCCGGGGCTGCACCGTCCTCACCCGGGCGTGGATGAGCTTGTTGACCTGCTTCTTGACGCCACCTGTGAAGTTCTCAAAGGTGGGGTCAGGCACGTACTCGAAGGCCCCGGCCTCTGTTCTGAGCAGGGCACGGTGCCCGTCCAT...
Task1_train_48827	This variant lies on Chromosome 22. Based on this context, is the mutation pathogenic or benign? If pathogenic, what disease does it cause?	Benign	CGAAGGCCCCGGCCTCTGTTCTGAGCAGGGCACGGTGCCCGTCCATCTCGATCAGCACCGTGAGGTTGTAGGCCTCTGGCTCCTCAGGCACAGCCGGGGACAGGAAGACGACCTTGGTGTCATTGTGGAACACGTAGTCTGTACCCACCACCTGCAGGCAAGTCCCAGCTGTCAGCCCCCGGGCGCAGACCCCGCCCTTCCTGGGCACGATCCCATGGGCCGGTGCCAGAGCTGAGCCCACGCCAGGACTGACCGTCATGGGCTGCAGGGATTCAGCCTCCCGCGGCGGCTGCCAGGACTGCAGGGGCTCCGCGATGACC...	CGAAGGCCCCGGCCTCTGTTCTGAGCAGGGCACGGTGCCCGTCCATCTCGATCAGCACCGTGAGGTTGTAGGCCTCTGGCTCCTCAGGCACAGCCGGGGACAGGAAGACGACCTTGGTGTCATTGTGGAACACGTAGTCTGTACCCACCACCTGCAGGCAAGTCCCAGCTGTCAGCCCCCGGGCGCAGACCCCGCCCTTCCTGGGCACGATCCCATGGGCCGGTGCCAGAGCTGAGCCCACGCCAGGACTGACCGTCATGGGCTGCAGGGATTCAGCCTCCCGCGGCGGCTGCCAGGACTGCAGGGGCTCCGCGATGACC...
Task1_train_48828	A variant on Chromosome 22 is under investigation. Evaluate whether it is clinically benign or pathogenic and name the disorder if relevant.	Benign	GTCCCAACAGCTCCCAGCATGGGGGAGCCCCCACCTGGCCCGGCCTGGGGCCCAGGACCCCCACCCCAGACCCACCACGCACCTCCCCCTGGGCCCGCCGGCTCATGTTCTGTGGCTGGGCGCTGGTGACGGCCACGCAGGACTTGCTTCGGCTCCACAGCCAGTGGCTGGCCTCCTCGGCCCGCGGACACTCGGCCTTCCGGGTGCATCTGCAGGCGCAGGGGGCGGCCTCAGCCCAGGGTGGAGTCTTGTTCTCCCGGGACAGGACAGTGCGATGTGCCCCCCGACCCAGGCCACGACCTTCCGGGATCCCAGAGGCA...	GTCCCAACAGCTCCCAGCATGGGGGAGCCCCCACCTGGCCCGGCCTGGGGCCCAGGACCCCCACCCCAGACCCACCACGCACCTCCCCCTGGGCCCGCCGGCTCATGTTCTGTGGCTGGGCGCTGGTGACGGCCACGCAGGACTTGCTTCGGCTCCACAGCCAGTGGCTGGCCTCCTCGGCCCGCGGACACTCGGCCTTCCGGGTGCATCTGCAGGCGCAGGGGGCGGCCTCAGCCCAGGGTGGAGTCTTGTTCTCCCGGGACAGGACAGTGCGATGTGCCCCCCGACCCAGGCCACGACCTTCCGGGATCCCAGAGGCA...
Task1_train_48829	A variant has been detected on Chromosome 22. What is its effect — pathogenic or benign? If pathogenic, name the disease.	Benign	ACTATATGCAAAATAGCCTCCCATCCCCAGACAAGACGGGGGCTGTGTCAGGAGAGGGTCCCTCCTGTCCTGGGCAGCCTGTTGGGCTGAGGGAAGCATCACACACAGCGCAGGGGGGTCGGGGGCCAACAGATGGGCACCGGGAGGGGCAGACGGTAGACGCACCCACATCAGCAAGGGCTCCCAGCCTGTCCCCGCCCCCGTCCCAGCCTAAGGTCTGCAGAGGCCAGGTGGGACCCAGGAGGAGGCAAGGCTCTGCCTGCGAGGAACCCCTATGGTCAAGGCCATGCTGTGGTTCCAAATGTCGCCTTTACTGCTGA...	ACTATATGCAAAATAGCCTCCCATCCCCAGACAAGACGGGGGCTGTGTCAGGAGAGGGTCCCTCCTGTCCTGGGCAGCCTGTTGGGCTGAGGGAAGCATCACACACAGCGCAGGGGGGTCGGGGGCCAACAGATGGGCACCGGGAGGGGCAGACGGTAGACGCACCCACATCAGCAAGGGCTCCCAGCCTGTCCCCGCCCCCGTCCCAGCCTAAGGTCTGCAGAGGCCAGGTGGGACCCAGGAGGAGGCAAGGCTCTGCCTGCGAGGAACCCCTATGGTCAAGGCCATGCTGTGGTTCCAAATGTCGCCTTTACTGCTGA...
Task1_train_48830	A variant has been detected on Chromosome 22. What is its effect — pathogenic or benign? If pathogenic, name the disease.	Benign	CAGGACAGAAGGGCCTTGGGTCCCATGCCAGGCAAGGACAGGGCGGGGGGGGGGCGAGGACAGGGCGGGGGGGCGGCGAGGACAGGGTGGGGGGGCGGCGAGGACAGGGCGGGGGGCCCCGAGGACAGGGTGGGGGGGGGCGGCGAGGACGGGGGGGGGGCGGCGAGGACAGGGCGGGGGGCCGCGAGGACAGGGTGGGGGGGGGCGGCGAGGACAGGGTGGGGGGGTGGCGAGGACAGGGTGGGGGGCGGCGAGGACAGGGTGGGGGGGCGGCAAGGAGAGCTGGACACAGCCCAGGTGGGGCTGCAGGAGGGGTGGGC...	CAGGACAGAAGGGCCTTGGGTCCCATGCCAGGCAAGGACAGGGCGGGGGGGGGGCGAGGACAGGGCGGGGGGGCGGCGAGGACAGGGTGGGGGGGCGGCGAGGACAGGGCGGGGGGCCCCGAGGACAGGGTGGGGGGGGGCGGCGAGGACGGGGGGGGGGCGGCGAGGACAGGGCGGGGGGCCGCGAGGACAGGGTGGGGGGGGGCGGCGAGGACAGGGTGGGGGGGTGGCGAGGACAGGGTGGGGGGCGGCGAGGACAGGGTGGGGGGGCGGCAAGGAGAGCTGGACACAGCCCAGGTGGGGCTGCAGGAGGGGTGGGC...
Task1_train_48831	Assess the clinical impact of this variant found on Chromosome 22. State whether it’s pathogenic or benign, and the disease if applicable.	Benign	GGACAGGGTGGGGGGGGGCGGCGAGGACGGGGGGGGGGCGGCGAGGACAGGGCGGGGGGCCGCGAGGACAGGGTGGGGGGGGGCGGCGAGGACAGGGTGGGGGGGTGGCGAGGACAGGGTGGGGGGCGGCGAGGACAGGGTGGGGGGGCGGCAAGGAGAGCTGGACACAGCCCAGGTGGGGCTGCAGGAGGGGTGGGCACTGCTGGAGGCTCAGGCCCCTTGCCCGCCCACAGCCCCTCCTGCTGCCTGCCAGCTCCTGCCGCTCTTGAGGTGCCAGCCCAGAGTGGCCAAGCAGCGCACCTTCTGGAAGTAGCCCCTCT...	GGACAGGGTGGGGGGGGGCGGCGAGGACGGGGGGGGGGCGGCGAGGACAGGGCGGGGGGCCGCGAGGACAGGGTGGGGGGGGGCGGCGAGGACAGGGTGGGGGGGTGGCGAGGACAGGGTGGGGGGCGGCGAGGACAGGGTGGGGGGGCGGCAAGGAGAGCTGGACACAGCCCAGGTGGGGCTGCAGGAGGGGTGGGCACTGCTGGAGGCTCAGGCCCCTTGCCCGCCCACAGCCCCTCCTGCTGCCTGCCAGCTCCTGCCGCTCTTGAGGTGCCAGCCCAGAGTGGCCAAGCAGCGCACCTTCTGGAAGTAGCCCCTCT...
Task1_train_48832	A mutation located on Chromosome 22 is being studied. Determine whether it’s pathogenic or benign, and specify the linked disease.	Benign	AGCAGGTGTTCCCAGTTGTGTGAGGGTGCTGAGGCCCCCGATGAGCACCGGGGGAGGAGCACTGAGGCCCCAGATGAGCAGTGGGCCTGGAGGAACGCTGAAGCCATCCCCCTTGCTCTTGCAGTGCCCCGTTTGACAGGATCGCAGAGATCAACTTCAACATCGACGCTGACGAGGACAGTGTGAGCAAGCCGGGCTGTGTGGGGTGCCGCCACCCTTTTCCCAGGCAGCTCAGGCCATGCCCATGGCTCGGTCTGTCATGGGCCTGTGCGGTGGGGCTGGGAGAGGCCCCTCTGTGGAGCTCGGAACAGTCGCTTTCC...	AGCAGGTGTTCCCAGTTGTGTGAGGGTGCTGAGGCCCCCGATGAGCACCGGGGGAGGAGCACTGAGGCCCCAGATGAGCAGTGGGCCTGGAGGAACGCTGAAGCCATCCCCCTTGCTCTTGCAGTGCCCCGTTTGACAGGATCGCAGAGATCAACTTCAACATCGACGCTGACGAGGACAGTGTGAGCAAGCCGGGCTGTGTGGGGTGCCGCCACCCTTTTCCCAGGCAGCTCAGGCCATGCCCATGGCTCGGTCTGTCATGGGCCTGTGCGGTGGGGCTGGGAGAGGCCCCTCTGTGGAGCTCGGAACAGTCGCTTTCC...
Task1_train_48833	Given a variant located on Chromosome 22, assess whether it is benign or pathogenic. Indicate the associated disease if pathogenic.	Benign	TGAGAATCCCCCTACCCTCGAAGGCCGCCCTAACAACTTCCCATCCGCTGACCCCTCCAACGCCATCAATCTCCAGCTGTGGTTGTTGAACTCGGAGGTGAGCTCCTCTCACCACTCTCTTGAATAAAGCTTTTCTCACCATTTTAACAAGTCCTCAGAATCATCTTTTCTTAACAAGCTCCTGCCCCACCCAGAATCACGGGGGGCCTGGGGACAAGTTTTCACCTCCTGAGATCCAGTGGGGCAGCCGGGGAAGGGGTGGTGCAGAGGGGGCGTGTGCTTGAGGGTGGGGTCTTGGGTCTGCCCCTACTTGTGGGACC...	TGAGAATCCCCCTACCCTCGAAGGCCGCCCTAACAACTTCCCATCCGCTGACCCCTCCAACGCCATCAATCTCCAGCTGTGGTTGTTGAACTCGGAGGTGAGCTCCTCTCACCACTCTCTTGAATAAAGCTTTTCTCACCATTTTAACAAGTCCTCAGAATCATCTTTTCTTAACAAGCTCCTGCCCCACCCAGAATCACGGGGGGCCTGGGGACAAGTTTTCACCTCCTGAGATCCAGTGGGGCAGCCGGGGAAGGGGTGGTGCAGAGGGGGCGTGTGCTTGAGGGTGGGGTCTTGGGTCTGCCCCTACTTGTGGGACC...
Task1_train_48834	A variant on Chromosome 22 is under investigation. Evaluate whether it is clinically benign or pathogenic and name the disorder if relevant.	Benign	GAGGCTCCTCTGTGATCAGGCAGTGGGCAACACCAAGCCAGGCCTCTTCAGAGAGAATGCTGAGGACGGGGCAGGAGGGTGCCCAGGGAGCCACGCCGTGGCGGAGCCTGACTGTGCTCTGGGCGGCCCACTGCCTGGGGCAGGGGAGACAATCCCATCCTCATGCCTCCTGGGAAAGCAGCACCAGGCACACAGCCAAGCACAAAAGACGCCTTTATTGGTGCCCAGATCTAAAGGGCAGGATGGGCTGGTGTGAAGATGACGTGGAAGATGACAGTGCTTCCCCTCTTCCCCTGGGAGTCAGCCTCTTCCCCTCTGGC...	GAGGCTCCTCTGTGATCAGGCAGTGGGCAACACCAAGCCAGGCCTCTTCAGAGAGAATGCTGAGGACGGGGCAGGAGGGTGCCCAGGGAGCCACGCCGTGGCGGAGCCTGACTGTGCTCTGGGCGGCCCACTGCCTGGGGCAGGGGAGACAATCCCATCCTCATGCCTCCTGGGAAAGCAGCACCAGGCACACAGCCAAGCACAAAAGACGCCTTTATTGGTGCCCAGATCTAAAGGGCAGGATGGGCTGGTGTGAAGATGACGTGGAAGATGACAGTGCTTCCCCTCTTCCCCTGGGAGTCAGCCTCTTCCCCTCTGGC...
Task1_train_48835	A sequence alteration has been identified on Chromosome 22. Is it disease-inducing or harmless?	Benign	CTGCCCGCCCTGGGAGGGCTCACCGTCCAGTGGTGGCCGTCGTAACTGCCCTCCAGCACCACCTCAGGCCGTCCACCAAGCCCAGTCATGCGGCGGAAGAGGCCGTAGGAGTTGGCCAGCTGTAGGTGCTCCACGGCACCAAACAGGCGGTGGGCCCCGGTCCAGAGGCGCCCGTGGGTCCCGGGCTCCACGTAGGAGTACGGCACCTGGAGACAGGTGGGAGGTTCTCAGGGCTGCCCTGCCCCCAGCCCATCCCCCAGCCCTGCAGCGCTACCCACCAGGCTAATCAGGAACAAGGCCACGGTCGCAGTGCCCACAAG...	CTGCCCGCCCTGGGAGGGCTCACCGTCCAGTGGTGGCCGTCGTAACTGCCCTCCAGCACCACCTCAGGCCGTCCACCAAGCCCAGTCATGCGGCGGAAGAGGCCGTAGGAGTTGGCCAGCTGTAGGTGCTCCACGGCACCAAACAGGCGGTGGGCCCCGGTCCAGAGGCGCCCGTGGGTCCCGGGCTCCACGTAGGAGTACGGCACCTGGAGACAGGTGGGAGGTTCTCAGGGCTGCCCTGCCCCCAGCCCATCCCCCAGCCCTGCAGCGCTACCCACCAGGCTAATCAGGAACAAGGCCACGGTCGCAGTGCCCACAAG...
Task1_train_48836	A mutation found on Chromosome 22 may be clinically relevant. Is it pathogenic or benign, and if the former, which disease is implicated?	Benign	TGTGGGGCTCCGAGTCAGCAGCAGCATGGATCTGATGCTCCTGGAAACAAGCACAGGCGTCAGGAGCCAGAAGGGAAGGCCCAGGACAGTGCCTGGGCTGCCCCTGCGACTTGAGACCAGCCACCCATCTGAAGGACCCAGCCCACGTTCAGGCTTAACAGGCATTTGCAGCTGCTCACCTGAGCTCAGAACTCCACCTCCACCAAACATCCACACCTGGGCAACCACACCTGTCACTCCTGTCCTCTACCTGGGATCACCAGCCTGTCACCGCACCCTGCCCTGCACCTGCACCTCAGCAAGGTGAACCTCTTGCTGAC...	TGTGGGGCTCCGAGTCAGCAGCAGCATGGATCTGATGCTCCTGGAAACAAGCACAGGCGTCAGGAGCCAGAAGGGAAGGCCCAGGACAGTGCCTGGGCTGCCCCTGCGACTTGAGACCAGCCACCCATCTGAAGGACCCAGCCCACGTTCAGGCTTAACAGGCATTTGCAGCTGCTCACCTGAGCTCAGAACTCCACCTCCACCAAACATCCACACCTGGGCAACCACACCTGTCACTCCTGTCCTCTACCTGGGATCACCAGCCTGTCACCGCACCCTGCCCTGCACCTGCACCTCAGCAAGGTGAACCTCTTGCTGAC...
Task1_train_48837	Chromosome 22 carries this variant. Does this mutation lead to a specific disease, or is it non-pathogenic?	Benign	GGTTTCTAAGGGATCCAGGTGCTGGCTGATGCGGTAACTGGAGTAGGGGGCAGGCTGGGCTCAGGGTTCTCCAGGGGCACAGTGAGAGTCTCATCTGGGCAGTCAAGACACTCTCGATGGGCGCAGGGGGTCCAGGAGATCCTAGAAGGTCTAGGTGGGCTGAAATAAGCCTGGCCATAAAGAGAGAAATATGTTTGGATTTTATTTATCCCATTAATTTTTTTTTTCTCTTGACTTGATAACCCTATCCCATGTCTGGTAAACCCAGAGTAAGGAGTCCAAAAGCTGCTGGAGGAGGAGCTATGGGAGCCTCAGTCTCC...	GGTTTCTAAGGGATCCAGGTGCTGGCTGATGCGGTAACTGGAGTAGGGGGCAGGCTGGGCTCAGGGTTCTCCAGGGGCACAGTGAGAGTCTCATCTGGGCAGTCAAGACACTCTCGATGGGCGCAGGGGGTCCAGGAGATCCTAGAAGGTCTAGGTGGGCTGAAATAAGCCTGGCCATAAAGAGAGAAATATGTTTGGATTTTATTTATCCCATTAATTTTTTTTTTCTCTTGACTTGATAACCCTATCCCATGTCTGGTAAACCCAGAGTAAGGAGTCCAAAAGCTGCTGGAGGAGGAGCTATGGGAGCCTCAGTCTCC...
Task1_train_48838	This variant is located on Chromosome 22. Evaluate its biological effect and specify any disease association.	Benign	TGCGGTAACTGGAGTAGGGGGCAGGCTGGGCTCAGGGTTCTCCAGGGGCACAGTGAGAGTCTCATCTGGGCAGTCAAGACACTCTCGATGGGCGCAGGGGGTCCAGGAGATCCTAGAAGGTCTAGGTGGGCTGAAATAAGCCTGGCCATAAAGAGAGAAATATGTTTGGATTTTATTTATCCCATTAATTTTTTTTTTCTCTTGACTTGATAACCCTATCCCATGTCTGGTAAACCCAGAGTAAGGAGTCCAAAAGCTGCTGGAGGAGGAGCTATGGGAGCCTCAGTCTCCTCTCTATGCCCCCTCCCTGTGCCCCAGTA...	TGCGGTAACTGGAGTAGGGGGCAGGCTGGGCTCAGGGTTCTCCAGGGGCACAGTGAGAGTCTCATCTGGGCAGTCAAGACACTCTCGATGGGCGCAGGGGGTCCAGGAGATCCTAGAAGGTCTAGGTGGGCTGAAATAAGCCTGGCCATAAAGAGAGAAATATGTTTGGATTTTATTTATCCCATTAATTTTTTTTTTCTCTTGACTTGATAACCCTATCCCATGTCTGGTAAACCCAGAGTAAGGAGTCCAAAAGCTGCTGGAGGAGGAGCTATGGGAGCCTCAGTCTCCTCTCTATGCCCCCTCCCTGTGCCCCAGTA...
Task1_train_48839	Here’s a variant located on Chromosome 22. What is the predicted biological effect — harmless or disease-causing?	Benign	GGCGGAGACAGGTGGTGTCAGGGCGTCCTCTCGCCAGGCCGCAGGCCCCGCGGGGCAACAGGACACTGGCCCCTGGCAGGCGGGCGCGGGGCCCTCGGGCTCGATGGGGAGAGGCCGGGGCCGGCGGCGGCGGATGGACGCTGGCTCGGGAGACAGAGCCCGCCGCCCCCGGAAACTGGACCCGCTCCGCCTGGGCGCCGCGGGGAGCGTGTGGGACGCGGTGGACGGGGCCGCCGCCCTGGACGCCCACGCGCGCGGCCTCCCCACAGGACCCCCACTCGCCCAGGAGCCCGCACTCCCGGCGCTGCCCGCTCCCCGCG...	GGCGGAGACAGGTGGTGTCAGGGCGTCCTCTCGCCAGGCCGCAGGCCCCGCGGGGCAACAGGACACTGGCCCCTGGCAGGCGGGCGCGGGGCCCTCGGGCTCGATGGGGAGAGGCCGGGGCCGGCGGCGGCGGATGGACGCTGGCTCGGGAGACAGAGCCCGCCGCCCCCGGAAACTGGACCCGCTCCGCCTGGGCGCCGCGGGGAGCGTGTGGGACGCGGTGGACGGGGCCGCCGCCCTGGACGCCCACGCGCGCGGCCTCCCCACAGGACCCCCACTCGCCCAGGAGCCCGCACTCCCGGCGCTGCCCGCTCCCCGCG...